Recently, Professor Chen Jiang from School of Pharmacy, Fudan University, has developed a biomimetic dendrimer-peptide nanoconjugate, which had the function of regulating the pro-inflammatory microenvironment of brain lesions and was used for early multi-target treatment of Alzheimer’s disease (AD)...

The "New Trends in Virtual Screening" special issue edited by Professor Renxiao Wang from the Department of Medicinal Chemistry, School of Pharmacy, is just published in the Journal of Chemical Information and Modeling (American Chemical Society) as the September issue (https://pubs.acs .org/toc/jci...

Cardiovascular disease (CVD) is a leading cause of death and loss of productive life years worldwide1. Atherosclerosis (AS) is the underlying pathological cause for the development of CVDs and the main contributor to cardiovascular mortality2. The predominant cells present in atherosclerotic plaques...

A novel liposome-leukocytes combination delivery system was designed for ischemic stroke target therapy. The study was published on “Science Advances”, with Prof. Jianxin Wang and associate Prof. Jing Qin as co-responding authors.

Recently, Lu Zhou's lab from School of Pharmacy, Fudan University, has published a paper entitled "A novel allosteric inhibitor of phosphoglycerate mutase 1 suppresses growth and metastasis of non-small cell lung cancer" in Cell Metabolism (impact factor 22.415), collaborated with Ying Shen's group ...

Recently, Professor Wei Lu from School of Pharmacy, Fudan University, has designed a new theranostic preparation using “hitchhiking technique” for the intraoperative fluorescence image-guided cancer photodynamic and checkpoint blockade therapy. The work has been published entitled “High affinity ...

Vision has profound influence on the quality of life. Up to now, the number of visually impaired patients worldwide is about 1.3 billion, of which 36 million are blind. Chronic posterior ocular diseases are the causal factors for severe vision impairment and even blindness, including hereditary reti...

Recently, Professor Wei Lu from School of Pharmacy, Fudan University, has used biomimetic technology to prepare an adjuvant for cancer vaccine. The work has been published entitled “Bacterium-Mimicking Vector with Enhanced Adjuvanticity for Cancer Immunotherapy and Minimized Toxicity” in Advanced ...

With the support of National Science Fund for Distinguished Young Scholars and National Natural Science Foundation of China, Prof. Chen Jiang’s group from Fudan University, jointed with Prof. Weigen Lu in China State Institute of Pharmaceutical Industry, led PhD student Yifei Lu and others who deve...

Recently, the team of Professor Xiaoyan Shen (School of Pharmacy, Fudan University) in collaboration with the team of Zheng Mingyue, a researcher at the Chinese Academy of Sciences Shanghai Institute of Materia Medica, has made new progress in the field of autophagy and colorectal cancer. On June 17...

Recently, Di Zhu, professor at the School of Pharmacy, and Yuxiong Feng, professor at Zhejiang University, have made new progress in the field of colorectal cancer immunotherapy. This research finding was published online in Science Advances, with the title of "Pharmacological inhibition of β-caten...

The limited chemotherapy effect of pancreatic cancer is related to its unique and complex tumor microenvironment (TME). The presence of dense extracellular matrix leads to the low permeability of traditional chemotherapy drugs, and the high toxicity of chemotherapy drugs restricts their clinical app...

Metastasis is the major cause of high mortality in cancer patients, thus metastasis suppression is the key and most challenging mission in cancer therapies. Many patients have generated micro-metastasis at the early stage, whereas conventional therapeutic methods or drugs are far less effective agai...

Recently, Professor Wei Lu of the School of Pharmacy, Fudan University and Professor Zeyu Xiao of the School of Medicine, Shanghai Jiaotong University reported a new theranostic preparation of albumin-bound near-infrared II small molecule. By means of intraoperative near-infrared fluorescence imagin...

Teams from Fudan University (Prof. Weiyue Lu’s lab) and University of California, San Diego (Prof. Liangfang Zhang’s lab) worked together to develop an active-targeting biomimetic nanomedicine based on red blood cell (RBC) membrane coating-drug nanocrystal (NC) for antiglioma therapy.

Epigenetic alteration like DNA hypermethylation plays a pivotal role in immune evasion of cancer cells during tumorigenesis. It is a common feature of heterogeneous cancer phenotypes for the reason that the tumor-associated antigen (TAA) promoter regions are hypermethylated in cancers, which lead to...

Recently, Professor Chen Jiang’s group from Fudan University School of Pharmacy developed a polymeric micelle drug delivery system with novel functions in modulating brain disease microenvironment and investigated its efficacy in treating Alzheimer’s disease (AD). The study was published on Advanc...

Recently, Professor Chen Jiang’s group from Fudan University School of Pharmacy developed a new type of prodrug-loaded ferric oxide nanoparticles, and relevant anti-tumor immunotherapy as well as microenvironment-responsive tumor MR imaging. The relevant studies were published online in Advanced Sc...

Triple-negative breast cancer (TNBC) is an extremely hard-to-treat subtype (~15%) of breast cancer. As TNBC lacks expression of human epidermal growth factor 2 (HER2), estrogen receptor (ER), and progesterone receptor (PR), traditional small-molecule inhibitors of therapeutic targets have little/no ...

Recently, the research about a novel smart anti-tumor nanomedicine was published online in Advanced Functional Materials. The work was led by Prof. Weiyue Lu of School of Pharmacy of Fudan University in partnership with Prof. Hao Wang of National Pharmaceutical Engineering Research Center. In this w...