Maintenance of cellular oxygen homeostasis is essential for ensuring the normal life activities of cells. William Kaelin, Jr., Sir Peter Ratcliffe, and Gregg Semenza shared 2019 Nobel Prize in Physiology or Medicine for discovering how cells sense and adapt to oxygen availability. Hypoxia inducible factor-1α (HIF-1α) is the key transcriptional factor for adapting to hypoxia. Increased HIF-1α protein level correlates with poor prognosis in cancer patients and tumor growth is significantly slowed
Recently, a cross-sectional study on prehospital delays among the stroke population in China, based on the Bigdata Observatory Platform for Stroke of China (BOSC), has been published online in The Lancet Regional Health -Western Pacific. This is the first study to report variations in prehospital delays according to age, rurality, and provinceusing a national prospective multicenter registry. This research was undertaken in collaboration with Dr. Jing Yuan from the School of Pharmacy, Prof. Jing