The center belongs to the Shanghai R&D Public Service Platform, and is also the important member of new drug R&D platforms for Fudan University School of Pharmacy.
Antiviral Drug Research Laboratory was established under the support and guidance of Prof. Wen Yumei in 1993. Since 2002, with continuous supports of National 211 and 985 Projects, the infrastructures and R&D capability have been greatly improved. In 2008, the Center for Anti-inflammation and Anti-virus Drug Screening formally became a sub-platform of the Shanghai R&D Public Service Platform.
Currently, our center has become the leading anti-viral drug screening and drug evaluation service platform in China and owns the powerful and comprehensive service capability, covering anti-virus, anti-bacterial and anti-inflammation drug evaluation. Especially for anti-virus drug screening, we have established the overall molecular, cellular and animal models for a series of viruses: Hepatitis B/C virus, HIV, Influenza and Coxsackie viruses, and so on.
In recent years, more than 5,000 compounds have been screened for universities, research institutes and enterprises, and efficacy evaluations for 7 drugs have been completed to assist enterprises in obtaining their clinical trial approvals.
Becoming a first-class antiviral drug screening center in China, and committing to hatching Chinese novel antiviral drugs.
R&D public service capability
The center currently has 10 full-time staff members, including 6 senior titles, many of whom have studied and worked in world-class anti-virus research laboratories.
ABSL 2 (P2 licensed) laboratory has 500 square meters for anti-viral cell experiments and 150 square meters of SPF-grade animal room for the virus-specific experiments. Our center owns all over regular equipment for virus-specific experiments.
Anti-virus, anti-bacterial and anti-inflammation drug screening, new drug preclinical drug efficacy evaluation and mechanism exploring.
Anti-virus: HBV, Influenza, HSV, RSV, Coxsackie, EV71 virus assay (Major center: Antiviral Drug Research Laboratory)
HCV assay (Prof. Yuan zhenghong group, The Key Laboratory of Medical Molecular Virology)
HIV assay (Prof. Xu jianqing group, Shanghai Public Health Clinical Center affiliated to Fudan University)
Anti-bacterial: Staphylococcus aureus, Streptococcus pneumonia, Klebsiella pneumonia, Helicobacter pylori, and so on.
Anti-inflammation: Hepatitis (Chemically damaging hepatitis, Alcoholic hepatitis, No-alcoholic fatty hepatitis), Arthritis and enteritis.