Dr. Jian Chen obtained his bachelor degree in Pharmacy from West China University of Medical Science (West China Center of Medical Sciences, Sichuan University) in 1999. He received his Ph.D. in Pharmaceutics from School of Pharmacy, Fudan University in 2009, and joined the same school as a faculty member after his graduation. Dr. Chen was appointed as the lecturer of the Department of Radiopharmacy at School of Pharmacy, Fudan University in 2009. He is a member of the Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, and a member of the China Nuclear Society (experimental nuclear medicine and nuclear pharmacy). Dr. Chen is engaged in scientific research about the radiolabeled molecular imaging probe of tumor and brain, and the application of radionuclide tracer technique in smart drug delivery system.
Radio-molecular Imaging; Radioisotope Tracer Technique
Education
2016-2017 Visiting Scholar, Johns Hopkins University, Medical School
2005-2009 Ph.D.in Pharmaceutics, Fudan University
2002-2005 M.Sc.in Radiopharmaceutics, Fudan University
1995-1999 B.Sc.in Pharmacy, West China University of Medical Science (West China Center of
Medical Sciences, Sichuan University)
Employment
Jul. 2009-present Lecturer, School of Pharmacy, Fudan University, Shanghai, China
Jul. 1999-Aug.2002 Director of Quality supervision department, SiChuan Sunnyhope LTD
Publications
6 papers as corresponding or first author. Total Impact Factor (IF) 27.34, total citations: 74.
Funding
1. Research Fund for the Doctoral Program of Higher Education of China (2013-2015)
2. Research Fund for the Shanghai Municipal Health Bureau (2011-2013)
Research Interests and Track Record
Dr. Jian Chen’s research focuses on tumor radio-imaging agent, self-assembling peptide nanotubes and radioisotope tracer technique. He mastered a lot of nuclear medicine techniques such as labeling and purification of radionuclides (125I、131I、99mTc、18F、3H、14C、177Lu、213Bi、255Ac), radioreceptor assays, radioimmunoassay, autoradiography, labeling and analysis of proteins, peptides, antibody drugs, in vivo imaging of small animals.
Publication List
1. Jian Chen, Bei Zhang, Fei Xia, Yunchang Xie, Sifan Jiang, Rui Su, Yi Lu and Wei Wu*. Transmembrane delivery of anticancer drugs through self-assembly of cyclic peptide nanotubes. Nanoscale, IF=7.76, 8(13)( 2016): 7127-7136
2. Feng Wang, Di Fan, Jun Qian, Zhe Zhang, Jianhua Zhu*, Jian Chen*. Preparation and Biodistribution of Technetium-99m-Labeled Bis-Misonidazole (MISO) as an Imaging Agent for Tumour Hypoxia. Medicinal Chemistry , IF=1.458,11(7)(2015): 649-655
3. Zhiwen Zhang#, Baohua Niu#, Jian Chen#, Xinyu He, Xiaoyue Bao, Jianhua Zhu, Haijun Yu, Yaping Li*. The use of lipid-coated nanodiamond to improve bioavailability and efficacy of sorafenib in resisting metastasis of gastric cancer. Biomaterials, IF=8.387, 35(2014): 4565-4572
4. Bei Zhang#, Jian Chen#, Yi Lu, Jianping Qi, Wei Wu*. Liposomes interiorly thickened with thermosensitive nanogels as novel drug delivery systems. International Journal of Pharmaceutics, IF=3.994, 455(2013): 276-284
