Keywords of research interests

Quantitative pharmacology; Adverse drug reactions

Curriculum Vitae

Education

1978.9-1982.7  School of Medicine, Tongji Medical University, undergraduate student, specialty: clinical medicine

1982.9-1985.7  Department of Pharmacology, Wannan Medical College, postgraduate student,  specialty: Pharmacolgy, obtained the degree of Master

1990.3-1991.3  Faculty of Pharmaceutical Sciences, Teikyo University, Japan, visiting scholar

1995.9-1996.9  Faculty of Pharmaceutical Sciences, Kyoto University, Japan, advanced visiting scholar sent by Chinese National Educational Committee

1997.9-2000.6  School of Graduate Studies, Shanghai Medical University,

specialty: Clinical Pharmacolgy, obtained Ph D degree

Professional Experiences

Assistant      Dept. of Pharmacology, Wannan Medical College, 1985.7-1987.6

Lecturer       Dept. of Pharmacology, Wannan Medical College, 1987.6-1993.6

Associate Professor  Dept. of Pharmacology, Wannan Medical College, 1993.6-1997.9

Associate Professor  Dept. of Pharmacology, School of Pharmacy, Fudan University, 2000.7-2001.11

Professor & Chairman   Dept. of Pharmacology, School of Pharmacy, Fudan University,  2001.11-present

Teaching Activities

Courses for undergraduate students (as the chief teacher)

1. Pharmacology:  compulsory course, national top-quality course

2. Drugs, life and society: Shanghai top-quality course

3. Clinical Pharmacology：elective course

4. Seminar on selected topics of pharmacology

Courses for postgraduate students

1. Experimental design and data analysis in pharmacology

2. Clinical Pharmacology

3. Adverse drug reactions

Awards & Honors

2009  Famous teacher award, Fudan University

Memberships

1. Standing council member，Chinese Pharmacological Society

2. Council member, Shanghai harmaceutical Association

3. Executive editor-in-chief， 《Chinese Journal of  Clinical Pharmacy》

Selected Publications（latest 5 yrs，<20 papers）

*Corresponding author

1. WENG Hongbo, LIU Yulan, CHENG Nengneng *, et al.:Neuroprotective effects of daidzein on cerebral ischemia and reperfusion in gerbils. Chin J Clin Pharmacy 2012; 21(5): 265-270

2. Taomin Huang ,Xiaoxia Li, Shuang Hu, Bo Zhao, Ping Chen,  Xiao Liu,  Deyong Ye, Nengneng Cheng*: Analysis of Fluorescent Ceramide and Sphingomyelin Analogs:A Novel Approach for in Vivo Monitoring of Sphingomyelin Synthase Activity. Lipids 2014;49:1071-1079

3. Jia-ShengWu, YuanLiu, RongShi, XiongLu, Yue-Ming Ma, Neng-NengCheng*: Effects of combinations of Xiexin decoction constituents on diabetic nephropathy in rats. Journal of Ethnopharmacology 2014; 157; 126-133

4. Ping Chen, Xiuwen Zhang, Taomin Huang, Qianqian Yu, and Nengneng Cheng*: Metabolism of the Hepatotoxic Compound Sophoraflavanone G in Rat Liver Microsomes.  Journal of Food Science 2014;79（7）：T1462-T1468

5. Yuan-Yuan Liu, Dou Yin, Li Chen, Wei-Min Qu, Chang-Rui Chen,  Moshe Laudon,  Neng-Neng Cheng*, et al: Piromelatine exerts antinociceptive effect via melatonin, opioid, and 5HT1A receptors and hypnotic effect via melatonin receptors in a mouse model of neuropathic pain. Psychopharmacology 2014:DOI10.1007/s00213-014-3530-5

6. Xiuwen Zhang, Peng Jiang, Ping Chen, and Nengneng Cheng*: Metabolism of kurarinone by human liver microsomes and its effect. Pharmaceutical Biology DOI:10.3109/13880209.2015.1070876,1-9

7. Dou Yin, Yuan-Yuan Liu, Tian-Xiao Wang,  Zhen-Zhen Hu,  Wei-Min Qu, Jiang-Fan Chen, Neng-Neng Cheng*, et al:  Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology, 2015; DOI 10.1007/s00213-015-4108-6

8. Peng Jiang,Qian Wang, Yi-Qun Jia, Rong Shi, Yue-Ming Ma, Ping Liu, Cheng-Hai Liu, Fu-Yuan Ye and Neng-Neng Cheng*. Identification and pharmacokinetics of the major constituents of Fugan Fang in rat plasma. RSC Adv., 2015,5(28): 21786-21796

9. Jia-Sheng Wu, Rong Shi, Xiong Lu, Yue-Ming Ma, Neng-Neng Cheng*: Combination of Active Components of Xiexin Decoction Ameliorates Renal Fibrosis Through the Inhibition of NF-κB and TGF-β1/ Smad Pathways in db/db Diabetic Mice. PLoS ONE 2015, 10 (3): e0122661

10. Dou Yin,  Yuan-Yuan Liu, Tian-Xiao Wang, Zhen-Zhen Hu, Wei-Min Qu, Jiang-Fan Chen, Neng-Neng Cheng*, et al: Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology 2016; 233:281–293

11. Peng Jiang , Xiuwen Zhang , Yutong Huang , Nengneng Cheng * and Yueming Ma: Hepatotoxicity induced by Sophora flavescens and hepatic accumulation of kurarinone, a major hepatotoxic constituent of Sophora flavescens in rats. Molecules 2017, 22, 1809; doi:10.3390.