Dr. Hong-Bo Weng finished her undergraduate and graduate education in Shenyang pharmaceutical university, and got her PH.D degree at 2008 from school of pharmacy, Fudan University. She has been working in department of pharmacology, school of pharmacy since 1997 until today. From 2009.12-2011.7, She was in Dr. Reece Lab as a post-doctoral. His research concentrated on the mechanism of infant defects induced maternal diabetes.
Diabetes; Inflammation; Traditional Chinese herb
Education
2008 Ph.D. in Pharmacology, Fudan University
1997 M.S. in Pharmacology, Shenyang Pharmaceutical University
1994 B.S. in Pharmaceutics, Shenyang Pharmaceutical University
Professional Experiences
2009-2012 University of Maryland, Baltimore Lund, Sweden, Visiting Scholar
1997-present Fudan University, Instructor
Teaching Activities
1. Courses taught: Pharmacology, Introduction of Pharmacology, Basic medicine, Human Anatomy and Physiology, Pharmacology Experiment, Molecular pharmacology Experiment
2. Licensed pharmacist training
3. Supervisor of 4 master’s candidates and 25 undergraduate students
Grants & Projects
2017-2020: sponsored by the National Natural Science Foundation of China
Therapeatical effect of Bupleurum polysaccharides on diabetes nephyropathy through suppressing HMGB1-TLR2/4 pathway based on Jiedutongluo
2011-2012: sponsored by Science and Technology Commission of Shanghai Municipality
Antiasthmatic effect studies of analogues of forskolin on guinea pig isolated bronchioles
2004-2006: sponsored by Science Foundation for Intramural Young Teachers of Fudan University
Effect of amylin on the process of secondary sulfonylurea failure
2002-2003: sponsored by Qipower, Inc. of Japan
Hypoglycemic and antihypertensive effects of Qi salt
Awards & Honors
2016, 2007 Excellent Teacher Award in School of of Pharmacy, Fudan University
2005 Advanced Worker in School of of Pharmacy, Fudan University
Memberships
1. Member, Chinese Pharmacological Society
2. Member, Chinese Pharmaceutical Association
Selected Publications（latest 5 yrs，<20 papers）
1. Hongbo Weng#, Wenke Han#, Yanwen Xiong, Huizhou Jin, Zhen Lan, Cheng Liu, Xuemei Zhang*, Wen Peng*. Taxus chinensis ameliorates diabetic nephropathy through down-regulating TGF-β1/Smad pathway, Chinese Journal of Natural Medicines, 2018, 16(1)
2. Rui Ma, Hongbo Weng* , Jianying Liang*. Screening of lipase inhibitors in Folium Mori with lipase-linked magnetic microspheres by high-performance liquid chromatography and evaluation in diabetic mice, J Sep Sci, 2016, 39(23):4474-4483.
3. Fang Wang#, Hongbo Weng#, Michael J. Quon, Jingwen Yu#, E. Jian-Ying Wang, Anne-Odile Hueber, Peixin Yang *, FADD dominant negative dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy, American Journal of Physiology-endocrinology and Metabolism, 2015, 309(10): E861- E873
4. Lingyu Pan#, Hongbo Weng#, Hong Li*, Zhenzhen Liu, Yanyan Xu, Chunjiao Zhou, Xiaoxiao Lu, Xiaoyu Su, Yunyi Zhang, Daofeng Chen*, Therapeutic Effects of Bupleurum Polysaccharides in Streptozotocin Induced Diabetic Mice, PLoS ONE, 2015, 10(7): e0133212
5. Hongbo Weng, Xuezheng Li, E. Albert Reece, Peixin Yang*, SOD1 suppresses maternal hyperglycemia-increased iNOS expression and consequent nitrosative stress in diabetic embryopathy, American Journal of Obstetrics and Gynecology, 2012, 206, 448.e1-448.e7
6. Xuezheng Li#, Hongbo Weng#, Cheng Xu, E. Albert Reece and Peixin Yang*, Oxidative stress- induced JNK1/2 activation triggers pro-apoptotic signaling and apoptosis that leads to diabetic embryopathy, Diabetes, 2012, 61(8): 2084-2092
