2008/09 - 2012/06:Lanzhou University, Bachelor.
2012/09 - 2015/06:Sun Yat-sen University,Master
2015/09 - 2018/06:Fudan University,PhD
Work Experience
2018/09- to date: National Institute of Allergy and Infectious Diseases,NIH, USA, Postdoctoral fellow
Project & Funding
1. Identification of co-receptor and components involved in the entry of SARS-CoV-2 using quantitative phosphoproteomic approach, 2020.6-2021.9, $500,000
Invited Presentations
1. Malaria and vector biology Seminar, LIG Work-in Progress:Searching for co-receptors for the entry of SARS-CoV-2 into host cells, 2021
2. Malaria and vector biology Seminar, LIG Work-in Progress:Connecting Membrane
Receptors to Intracellular transport,2019
Selected Publications
1. You Y, Bao WL, Zhang S, et al. Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway. Circ Res, 2020;127:534–549. (IF=17.6)
2. Bao W*, Liu X*, You Y*, et al. Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation. Pharmacol Res. 2021 May 16; 169:105679. (IF=5.892)
3. You Y and Sharmila GR. A crisper-based method for testing the essentiality of a gene. Sci Rep. 2020 Sep 8;10(1):14779. (IF=4.3)
4. Fan YJ, Yang JL and You Y#. SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis. CJC, 2020 May 16; S0828-282X(20)30456-6. Corresponding Author (IF=5)
5. You Y, Li WZ, Zhang S, et al. SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy. J Hepatol. Jul 2018;69(1):129-141. (IF=25.03)
6. You Y, Zhou C, Li D, et al. Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis. Sci Rep. 2016; 6: 20630. (IF=3.997)
7. Zhou C, You Y, Zhu YZ, et al. Deficiency of sorting nexin 10 prevents bone erosion in collagen induced mouse arthritis through promoting NFATc1 degradation. Ann Rheum Dis. 2016; 75:1211-8. (IF=16)