Dr. Yu Sun wasborn in Rizhao, Shandong, China in 1988. In 2011, he obtained his B.Sc. atFudan University. He then moved to Shanghai Institute of Organic Chemistry (SIOC),Chinese Academy of Sciences for graduate study under the supervision of Prof.Ang Li, and received his Ph.D. in 2016. After a short stay in SIOC, he joinedProf. Amir H. Hoveyda’s group in Boston College as a postdoctoral fellow in2017. He started his independent career as an associate professor in school ofpharmacy, Fudan University in 2020. His research interest mainly focused on thetotal synthesis of structurally and biologically interesting natural products.He received Chinese Academy of Sciences President Excellence Award (2014) andSpecial Symposium Award-Roche and Royal Society of Chemistry Symposium (2013).He was also selected as one of Reaxys PhD Prize Finalists in 2016.
Natural product synthesis;Catalytic reaction; Enantioselective reaction
Education
2011–2016 Ph.D. ShanghaiInstitute of Organic Chemistry, Chinese Academy of Sciences,China. Research Advisor: Professor Ang Li
2007–2011 B.Sc., School of Pharmacy,Fudan University
Professional Experiences
2020-present Associateprofessor, School of Pharmacy, Fudan University, China
2017–2020 PostdoctoralFellow, Department of Chemistry, Boston College, USA
Research Advisor: ProfessorAmir H. Hoveyda
2016–2017 Researchassociate, Shanghai Institute of Organic Chemistry, Chinese Academy ofSciences, China
Awards & Honors
2016 Selected as one of theReaxys PhD Prize Finalists
2014 Chinese Academy ofSciences President Excellence Award
2013 Special SymposiumAward, Roche and Royal Society of Chemistry Symposium
Selected Publications
1. Y.Sun, Y. Zhou, Y. Shi, J. del Pozo, S. Torker, and A. H. Hoveyda* Copper?Hydride-Catalyzed EnantioselectiveProcesses with Allenyl Boronates. MechanisticNuances, Scope, and Utility in Target-Oriented Synthesis, J. Am. Chem. Soc. 2019, 141, 12087.
2. Y.Sun, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li,* BioinspiredTotal Synthesis of Sespenine, Angew.Chem. Int. Ed.2014, 53, 9012.
3. Y.Sun, R. Li, W. Zhang, and A. Li,* Total Synthesis of Indotertine A andDrimentines A, F, and G, Angew. Chem.Int. Ed.2013, 52, 9201.
4. Y.Sun, Z. Meng, P. Chen, D. Zhang, M. Baunach, C. Hertweck, and A. Li,* Aconcise total synthesis of sespenine, a structurally unusual indole terpenoidfrom Streptomyces, Org. Chem Front. 2016, 3, 368.
5. H. Li, Y. Sun, Q. Zhang, Y. Zhu, S. Li, A. Li, and C. Zhang,* Elucidatingthe Cyclization Cascades in Xiamycin Biosynthesis by Substrate Synthesis andEnzyme Characterizations, Org. Lett.2015, 17, 306.
6. Q. Zhang, H. Li, Y. Sun, L. Yu, Y. Zhu, H. Zhu, L. Zhang, S. Li, Y. Shen, C. Tian,A. Li, H. Liu * and C. Zhang,* Characterization of the flavoenzyme Xia K as anN-hydroxylase and implications in indolosesquiterpene diversification, Chem. Sci. 2017, 8, 5067.
7. J. Pei, S. Zhou, F. Yang, Y. Sun, A. Li,* W. Zhang,* and W. He,*Identification and mechanistic studies of a cell cycle regulator JP18 from alibrary of synthetic indole terpenoid mimics, Chem. Asian J.2016, 11, 2715.
8. X. Xiong, D. Zhang, J. Li, Y. Sun, S. Zhou, M. Yang, H. Shao,* andA. Li,* Synthesis of Indole Terpenoid Mimics via a Functionality-ToleratedEu(fod)3-Catalyzed Conjugate Addition, Chem.Asian J.2015, 10, 869.
9. S. Zhou, D. Zhang, Y. Sun, R. Li, W. Zhang, and A. Li,* Intermolecular ConjugateAddition of Pyrroloindoline and Furoindoline Radicals to α,β-Unsaturated Enonesvia Photoredox Catalysis, Adv. Synth.Catal. 2014, 2867.
10. M. Bian, Z. Wang, X. C. Xiong, Y. Sun, C. Matera, K. C. Nicolaou,* andA. Li,* Total Syntheses of Anominine and Tubingensin A, J. Am. Chem. Soc.2012, 134, 8078.
