Professor Dr Qing Mu obtained his Ph.D. from Kunming Institute of botany of Chinese Academy of Science 1999. Now he was assigned as an editorial board member of the journal Phytochemistry Letters. Recent years Dr Mu focused on the chemical constituents against multidrug resistant microbial and anticancer compounds from plants of Chinese traditional medicines and ethnobotanical herbs. Professor Mu had formed a special research on natural inhibitors against multi drug resistance Methecilin-resistant Staphylococcus aureus (MDR MRSA) and found three efflux pump inhibitors from natural products. Now having established bioassay technique platform in his group, professor Mu engaged himself on the studies of synergetic natural substances from Chinese traditional medicines or medicinal herbs against multi drug resistant microbials. Based on natural occurring leading compounds, Professor Mu also synthese cyclic peptides for anti-drug resistant tumor.As a inentor professor Mu was authorised 9 Chinese innovation patents and publised 30 papers in SCI journals.
Phytochemistry; Medicinal Plants; Synergism; anti drug-resistance; Staphyllococus aureus
Education
Phytochemistry Ph. D. (1999), Master Degree, (1992), Kunming Institute of Botany, Chinese Academic Sicences. B.S. 1985, Xingjiang University, China
UCL School of Pharmacy, Visiting Scholar 2009.9-2010.8
Post Doctoral research fellow, 2003-2005, AmorePacific R&D Center, Korea
Post Doctoral research fellow , 2000-2001, Formal Shanghai Medical School
Teaching Activities
Food Nutrient Constituents, and Organic Structure Analysis are taught for bachelor students, and Natural Products Chemistry and Biological Chemistry are lectured for graduated and doctoral students.
Grants and Projects as Principal Investigator (PI)
NSFC 21672041, 21172041, 30772630, 30472068, 39770089, NSFC-RS 81011130165.
Invited Presentation
Presentation title: Chinese Medicines against bacterial Drug resistance via Synergism, 11th Natural Organic Chemistry Symposium of China 2016, Shanghai.
Selected Publication
1. Chen JT1, Ma R1, Sun SC, Zhu XF, Xu XL, Mu Q*. Synthesis and biological evaluation of cyclopeptide GG-8-6 and its analogues as anti-hepatocellular carcinoma agents. Bioorganic & Medicinal Chemistry. 2018,
2. Sun ZL ?, He JM ?, Lan JE and Mu Q*. High-Speed Counter-Current Chromatography with an Online Storage Technique for the Preparative Isolation and Purification of Dihydroflavonoids from Sophora alopecuroides L. Phytochemical Analysis 2017, 28: 496-504.
3. He JM, Zhang SY, Mu Q*. Online-storage recycling counter-current chromatography forpreparative isolation of naphthaquinones from Arnebia euchroma (Royle) Johnst. Journal of Chromatography A 2016, 1461: 79-86.
4. Sun ZL, He JM, Wang SY, Ma R, Khondkar P, Kaatz GW, Gibbons S and Mu Q*. Benzocyclohexane oxide and neolignan from Piper betle. RSC Advances 2016, 6: 43518–43525.
5. Wang SY, Sun ZL, Gibbons S, Mu Q*. Flavonoids from Sophora moorcroftiana and their synergistic antibacterial effects on MRSA. Phytotherapy Research 2013, 28: 1071–1076.
6. Liu T, Osman K, Kaatz GK, Gibbons, Mu Q*. Antibacterial sesquiterpenoid derivatives from Ferula ferulaeoides. Planta Medica 2013, 79: 701-706.
7. YH Zeng, K Osman, ZY Xiao, S Gibbons, Q Mu*.. Four geranyl-bearing polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. Phytochemistry Letters 2012, 5: 200–205.
8. W Wang, YH Zeng, K Osman, K Shinde, MM Rahman, S Gibbons, Q Mu*. Norlignans, acylphloroglucinols, and a dimeric xanthone from Hypericum chinense. Journal of Natural Products 2010, 73: 1815–1820.
9. Xiao ZY, Mu Q*, Shiu WPS, Zeng YH, Gibbons S. Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum sampsonii. Journal of Natural Products 2007, 70: 1779-1782.
Selected Patents
1. Chinese Patent. 2017. Inventors: Zhong-Lin Sun, Qing Mu, Shuang-Ying Wang, Simon Gibbons. A lignan compound and its manufacture in use of anti-drug resistant Staphyllcocus aureus. ZL2014100253185.
2. Chinese Patent. 2017. Inventors: Shuang-Ying Wang, Qing Mu, Zhong-Lin Sun, Simon Gibbons. A pharmaceutical combination against drug resistant Staphyllcocus aureus and the manufacture. ZL2013102792176.
3. Chinese Patent. 2014. Inventors: Qing Mu, Tao Liu, Hui-Qin Xie, Simon Gibbons, Khadijo Osman. Usage and manufacture for phenylpolyene compounds from Chinese medicine. ZL201110130562.4.
4. Chinese Patent. 2013. Inventors: Qing Mu, Jia Ye, Simon Gibbons, M. Mukhlesur Rahman, β,β-Dimethylacrylalkannin and its use against drug resistant bacteria. ZL200910054418x.
5. Chinese Patent. 2008. Inventors: Qing Mu, Dao-Feng Chen, Chang-Qi Hu. Anticancer compound Grifficyclocin Btogether with its analouges and their manufacture. ZL2005100239564.
