Dr. Bang-Guo Wei obtained his Ph.D. from Xiamen University in 2004. He worked for a post doctorate two years in Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences from 2004 to 2006. Dr. Wei joined the faculty of Department of Chemistry, Fudan University. In 2015, he joined the faculty of Department of Natural Products Chemistry, School of Pharmacy Fudan University. He is a young editors of Chinese Chemical Letters.
Asymmetric Synthesis; Natural Product; Total Synthesis
Education
09/2001-09/2004 Ph.D. Department of Chemistry, Xiamen University;
09/1998-07/2001 M.S. Department of Chemistry, Northwest Normal University;
09/1994-07/1998 B.S. Department of Chemistry, Northwest Normal University;
Professional Experiences
09/2004-08/2006 Postdoctoral Fellow Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences;
08/2006-06/2015 Associate Professor Department of Chemistry, Fudan University;
06/2015- present Professor School of Pharmacy, Fudan University
Teaching Activities
The Strategy and Science of Total Synthesis (Selective course for Doctoral students)
Grants & Projects
National Natural Science Foundation of China
Selected Publications (Representative works)
1. Zhuo-Ya Mao, Yi-Wen Liu, Pan Han, Han-Qing Dong, Chang-Mei Si,* Bang-Guo Wei* and Guo-Qiang Lin Regio- and Stereoselective Cascades via Aldol Condensation and 1,3-Dipolar Cycloaddition for Construction of Functional Pyrrolizidine Derivatives Org. Lett. 2018, 20, 1090-1093;
2. Pan Han, Zhu Zhou, Chang-Mei Si,* Xian-Yi Sha, Zheng-Yi Gu,* Bang-Guo Wei,* and Guo-Qiang Lin Asymmetric Synthesis of Rupestonic Acid and Pechueloic Acid Org. Lett. 2017, 19, 6732?6735;
3. Chang-Mei Si, Wei Huang, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Diastereoconvergent Synthesis of trans-5-Hydroxy-6-Substituted-2-Piperidinones by Addition-Cyclization-Deprotection Process Org. Lett. 2014, 16, 4328-4331;
4. Zhuo-Ya Mao, Chang-Mei Si, Yi-Wen Liu, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang Lin Divergent Synthesis of Revised Apratoxin E, 30-epi-Apratoxin E, and 30S/30R?Oxoapratoxin E J. Org. Chem. 2017, 82, 10830?10845;
5. Chang-Mei Si, Zhuo-Ya Mao, Han-Qing Dong, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Divergent Method to trans-5-Hydroxy-6-alkynyl/alkenyl-2-piperidinones: Syntheses of (-)-Epiquinamide and (+)-Swainsonine J. Org. Chem. 2015, 80, 5824-5833;
6. Wei Huang, Jian-Liang Ye, Wei Zheng, Han-Qing Dong, Bang-Guo Wei* Radical Migration?Addition of N-tert-Butanesulfinyl Imines with Organozinc Reagents J. Org. Chem. 2013, 78, 11229-11237;
7. Wei Huang, Rong-Guo Ren, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang Lin Diverse Synthesis of Marine Cyclic Depsipeptide Lagunamide A and Its Analogues J. Org. Chem. 2013, 78, 10747-10762.
8. Synthesis and structure revision of symplocin A Lu-Ping Shao, Chang-Mei Si, Zhuo-Ya Mao, Wen Zhou, Tadeusz F. Molinski,* Bang-Guo Wei* and Guo-Qiang Lin Org. Chem. Front., 2017, 4, 995–1004;
9. Chang-Mei Si, Zhuo-Ya Mao, Yi-Wen Liu, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Formation of Chiral trans-4-Hydroxy-5-Substituted 2-Pyrrolidinones: Syntheses of Streptopyrrolidine and 3-epi-Epohelmin A Org. Chem. Front. 2015, 2, 1485-1499;
10. Yi-Wen Liu, Rui-Jun Ma, Jia-Hang Yan, Zhu Zhou* and Bang-Guo Wei* Asymmetric synthesis of (-)-sedacryptine through a diastereoselective Mannich reaction of N,O-acetals with ketones Org. Biomol. Chem. 2018, 16, 771-779;
11. Chang-Mei Si, Lu-Ping Shao, Zhuo-Ya Mao, Wen Zhou and Bang-Guo Wei* An efficient approach to trans-4-hydroxy-5-substituted 2-pyrrolidinones through a stereoselective tandem Barbier process: divergent syntheses of (3R,4S)-statines, (+)-preussin and (-)-hapalosin Org. Biomol. Chem. 2017, 15, 649-661;
12. Wen Zhou, Xiao-Di Nie, Yu Zhang, Chang-Mei Si,* Zhu Zhou, Xun Sun and Bang-Guo Wei* A practical approach to asymmetric synthesis of dolastatin 10 Org. Biomol. Chem., 2017, 15, 6119-6131;
13. Yi-Wen Liu, Pan Han, Wen Zhou, Zhuo-Ya Mao, Chang-Mei Si*, Bang-Guo Wei* Asymmetric syntheses of epohelmins A and B by In-mediated allylation Org. Biomol. Chem. 2016, 14, 10714-10722.
