Dr. Yan Lu obtained her Ph.D. from Fudan University in 2006 and then joined the faculty of Department of Pharmacognosy, School of Pharmacy, Fudan University. From 2011 to 2012, she worked as a visiting scholar in the National Products Research Lab, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill. Dr. Lu is interested in the research on anti-tumor, anti-virus and anti-complement constituents from natural products, as well as the development and quality control of Chinese herbal medicine. She is also a council member of the Specialty Committee of TCM Pharmacognosy of World Federation of Chinese Medicine Societies and the Specialty Committee of TCM of Shanghai Pharmaceutical Association.
Pharmacognosy, TCM, bioactive natural products, quality control
Education
Ph.D. in Pharmacognosy, Fudan University, 2003-2006;
Master in Pharmacognosy, Shandong University of Traditional Chinese Medicine, 2000-2003.
Professional Experiences
2011-Present: Associate Professor, Department of Pharmacognosy, Fudan University, Shanghai, China;
2011-2012: Visiting Schloar, School of Pharmacy, the University of North Carolina at Chapel Hill, NC, USA;
2006-2011: Lecturer, Department of Pharmacognosy, Fudan University, Shanghai, China.
Teaching Activities
Selections of Advanced Pharmacognosy (for M.S. students);
Pharmacognosy (for B.S. students);
Brief introduction to Chinese traditional and herbal medicines (for B.S. students).
Research Interests
1. Anti-tumor, anti-virus and anti-inflammatory constituents from natural products;
2. Bioactive polysaccharides of TCMs;
3. Quality control for TCMs.
Grants & Projects
1. National Natural Science Foundation of China (General Program): Medicinal Material Foundation for Clearing Heat and Quality Evaluation of Multiple Origins of Traditional Tibetan Medicine ‘Yuanbai’. No. 81673690, PI, ￥570,000, 2017.1-2020.12;
2. National Drug Innovative Program supported by the Ministry of Science and Technology of China: Key Technologies on Quality Control of Polysaccharides. No. 2012ZX09301001-003, PI of a sub project, ￥783,700, 2012.1-2015.12;
3. National Natural Science Foundation of China (Youth Science Program): Anti-complementary Agents and Material Foundation of Heat-clearing and Detoxification in Herba Houttuyniae. No. 30801508, PI, ￥200,000, 2009.1-2011.12.
Memberships
1. Committee member of Division of TCM, Shanghai Pharmaceutical Association（2015-2019）
2. Council Member of Botanical Society of Shanghai（2017-2020）
3. Council Member of Specialty Committee of TCM Pharmacognosy of the World Federation of Chinese Medicine Societies（2014-2018）
4. Council Member of Specialty Committee of TCM Chemistry of the World Federation of Chinese Medicine Societies（2016-2020）
Selected Publications（latest 5 yrs，<20 papers）
1. Yan Lu1, Yun Jiang1, Lijun Ling, Yunyi Zhang, Hong Li, Daofeng Chen*. Beneficial effects of Houttuynia cordata polysaccharides on ‘two-hit’ acute lung injury and endotoxic fever in rats are associated with anti-complementary activities. Acta Pharmaceutica Sinica B, 2018 (2): 218-227.
2. J De, Y Lu*, L Ling, N Peng, Y Zhong*. Essential oil composition and bioactivities of Waldheimia glabra (Asteraceae) from Qinghai-Tibet plateau. Molecules, 2017, 22(3): 460.
3. P Jiang1, Y Lu1, DF Chen*.Qualitative and quantitative analysis of multiple components for quality control of Deng-Zhan-Sheng-Mai capsules by ultra high performance liquid chromatography tandem mass spectrometry method coupled with chemometrics. Journal of Separation Science, 2017, 40(3): 612-624.
4. P Jiang1, Y Lu1, DF Chen*. Authentication of Schisandra chinensis and Schisandra sphenanthera in Chinese patent medicines. Journal of Pharmaceutical and Biomedical Analysis, 2016, 131(8): 263-271.
5. RY Tian, Y Lu*, DF Chen*. Four new diterpenoids from the roots of Euphorbia pekinensis. Chemistry & Biodiversity, 2016, 13 (10): 1404-1409.
6. Yun Jiang, Yan Lu*, Yun-Yi Zhang, Dao-Feng Chen*. Anti-complementary constituents of Houttuynia cordata and their targets in complement activation cascade. Natural Product Research, 2014, 28(6): 407-410.
Patents
1. Yan Lu, Daofeng Chen, Yuquan Li, Kuo-Hsiung Lee. Lanostane triterpenoids as cytotoxic agents for the treatment of tumor. Chinese Invention Patent, No. ZL 201310385753.4;
2. Yan Lu, Daofeng Chen, Yuquan Li, Kuo-Hsiung Lee. 4-Aryltetralin lignans as cytotoxic agents for the treatment of tumor. Chinese Invention Patent, No. ZL 201310385949.3;
3. Yan Lu, Daofeng Chen, Yun Jiang, Pei Zhou, Hai Huang. Phenol derivatives as antiviral agents for the treatment of hepatitis B. Chinese Invention Patent, No. ZL 201110024324.5;
4. Yan Lu, Daofeng Chen. Fufang Jixueteng Capsule and its preparation methods. Chinese Invention Patent, No. ZL 200610029660.8.
