Education

2016.09-2021.06 Fudan University, Pharmacology, Ph.D.

2012.09-2016.06 Shenyang Pharmaceutical University, Pharmacy, B.S.

Professional Experiences

2025.03-Present School of Pharmacy, Fudan University

Young Principal Investigator

2021.06-2025.02 School of Pharmacy, Fudan University

Postdoctoral Fellow

Teaching Activities

Pharmacognosy (for B. S. students)

Pharmacology (for B. S. students)

Immunopharmacology (for M. S. students)

Frontiers in Pharmacology Research (for M. S. students)

Development and Research of New Chinese Medicines (for M. S. students)

New Advances in Drug Development (for Ph. D. students)

Grants & Projects

National Natural Science Foundation of China (Youth Project), PI, 2023.01-2024.12

China Postdoctoral Science Foundation Postdoctoral Innovation Talents Support Program, PI, 2022.07-2025.02

China Postdoctoral Science Foundation General Program, PI, 2021.11-2025.02

Fudan University Talent Startup Fund, PI, 2025.03-2028.05

Fudan University School of Pharmacy Songde Young Talent Cultivation Program, PI, 2025.03-2028.03

Awards & Honors

2023 National Natural Science Foundation of China Annual Outstanding Funding Achievement: Research on novel potential drug targets for treating inflammatory bowel disease

2023 Fudan University Outstanding Postdoctoral Fellow

10th Shanghai Pharmaceutical Association Pharmacology Youth Paper Report Conference, Grand Prize

2021 Fudan University Super Postdoctoral Incentive Program

Selected Publications（latest 5 yrs，<20 papers）

1. Weilian Bao#, Yan You #, Jiahui Ni#, et al, Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells, Science Advances, 2023, 9(35):eadh5016

2.Weilian Bao#, Jiaren Lyu#, Guize Feng#, et al，Aloe emodin promotes mucosal healing by modifying the differentiation fate of enteroendocrine cells via regulating cellular free fatty acid sensitivity，Acta Pharmaceutica Sinica B, 2024, 14(9):3964-3982

3. Weilian Bao#, Xiaohong Liu#, Yan You#, et al，Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation，Pharmacological Research, 2021, 169:105679

4. Yan You#, Welian Bao#, Sulin Zhang, et al, Sorting nexin 10 mediates metabolic reprogramming of macrophages in atherosclerosis through the Lyn-dependent TFEB Signaling Pathway, Circulation Research, 2020, 127:534-549

5.Weilian Bao#, Qibiao Wu#, Bin Hu, et al, Oral nanoparticles of SNX10-shRNA plasmids ameliorate mouse colitis, International Journal of Nanomedicine, 2021, 16:345-357

6.Weilian Bao, Keyuan You, Jiahui Ni, et al, Construction and application of a novel mouse model of colitis with the function evaluating effects of anti-inflammatory and pro-stemness, Fudan University Journal of Medical Sciences, 2022, 49:979-986

7. Linfeng Guo, Weilian Bao, Shuiyuan Yang, et al, Rhei Radix et Rhizoma in Xuanbai-Chengqi decoction strengthens the intestinal barrier function and promotes lung barrier repair in preventing severe viral, Journal of Ethnopharmacology, 2024, 319(Pt 2):117231

8. Shiyu Xue, Weilian Bao, Changyue Wang et al, In vitro nephrotoxicity and structure-toxicity relationships of eight natural aristolactams, Toxicon, 2025, 254:108214

9.Sulin Zhang, Zhiwen Yang, Weilian Bao, et al, SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC, Autophagy, 2020, 6(4):735-749

10. Guize Feng, Lijie Zhang, Weilian Bao, et al, Gentisic acid prevents colorectal cancer metastasis via blocking GPR81-mediated DEPDC5 degradation, Phytomedicine, 2024, 129:155615

11.Ziyan Xu, Changyue Wang, Weilian Bao, et al, In vitro nephrotoxicity and quantitative UPLC-MS analysis of three aristololactams in Houttuynia cordata, Journal of Pharmaceutical and Biomedical Analysis, 2023, 227:115289

Patents

Active Compounds for Inhibiting Intestinal Inflammatory Response, Authorized, ZL201911089415.X

Diacylhydrazide Structural Compounds, Preparation Method and Application Thereof, Authorized, ZL202010312884.X