Professor Jianxin Wang received his Ph.D. in Pharmaceutics from West China University of Medical Sciences in 1999. He worked for Shanghai Institute of Chinese Materia Medica from July 1999 to April 2005. He was awarded as “Shanghai Youth Model” in 2003 and “Shanghai labor model” in 2004. Dr. Wang joined the faculty of School of Pharmacy, Fudan University in 2005 and became the vice dean in 2012. He worked as a visiting scholar in the College of Pharmacy, University of Michigan form 2009 to 2010. Dr. Wang’s research interest areas include targeting drug livery, drug transport through biological barriers, in particular those of the GI tract and the blood-brain barrier, and the development of novel dosage form and new preparations. Dr. Wang has been the principle investigator of more than 20 projects funded by the government. He has published more than 120 papers, edited or co-edited 12 books, and holds 12 issued Chinese patents.
Nano-carrier based biomimetic & tumor drug delivery system; Sustained/controlled drug delivery system; Oral absorption mechanism and new dosage form of traditional Chinese medicine; New drug preparation development
Education
1996.9-1999.7 Ph.D., Pharmaceutics, School of Pharmacy, West China University of Medical Sciences, Chengdu, China
1993.9-1996.7 M.S., Pharmaceutics, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China
1989.9-1993.7 B.S., Pharmacy, School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou, China
Professional Experiences
2012.1-present Professor of Pharmaceutics, Department of Pharmaceutics, School of Pharmacy, Fudan University
2012.12-present Vice Dean, School of Pharmacy, Fudan University
2010.10-present Vice Director, Key Laboratory of Smart Drug Delivery, Ministry of Education & PLA
2009.7-2010.8 Visiting Scholar, College of Pharmacy, University of Michigan
2005.5-2012.1 Associate Professor of Pharmaceutics, Department of Pharmaceutics, School of Pharmacy, Fudan University
2007.6-2013.1 Director of the Department of Pharmaceutics, School of Pharmacy, Fudan University
2001.7-2005.4 Senior Engineer, Executive Vice Director, Shanghai Institute of Chinese Materia Medica
1999.7-2001.7 Engineer, Department of Pharmacy, Shanghai Institute of Chinese Materia Medica
Teaching Activities
Teaching courses: Biopharmaceutics and Pharmacokinetics, Drug Dosage Form and Treatment of Diseases, Research and Development of Traditional Chinese Medicine, Novel Technologies of Modern TCM Preparation.
Principle teacher of <Biopharmaceutics and Pharmacokinetics>, an Excellent course appraised by Shanghai Education Committee.
Awards & Honors
2014.5 “Excellent Technical Leader” by Shanghai Municipal Government
2011.12 The 1st Prize for the Improvement of Science and Technology by Sichuan Municipal Government
2011.10 “Excellent Young Scientist” by Chinese Pharmaceutical Association
2004.6 “Excellent League Member” by Shanghai State-owned Assets Supervision and Administration Commission
2004.5 “Working Model of Shanghai” in 2001-2003 by Shanghai Municipal Government
2003.5 “Excellent Youth of Shanghai” by Shanghai Municipal Government
2002.9 The 1st Prize of National Young Pharmaceutical Scientists by Chinese Pharmaceutical Association
Invited Presentations
1. Symposium of the R&D of Traditional Chinese Medicine. Innovation and Technology Commission, The Government of the Hong Kong Special Administrative Region. Hong Kong, September 20, 2016
2. 2016 International Symposium on Theranostic Nanomedicine, Taiwan, March 24-26, 2016
3. 17th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, USA. University of Utah. June 14-17, 2015
4. 1st International Symposium of Society for Therapeutics Delivery (STD), Seoul, Korea. Ewha Womans University. September 12-13, 2015
5. JSPS A3 Foresight International Symposium on Nano-Biomaterials and Regenerative Medicine. Japan Society for the Promotion of Sciences. Tokyo，Japan. October 8-9, 2014
Selected Publications
1. Jianming Liang, Ruixiang Li, Yuwei He, Chengli Ling, Qi Wang, Yongzhuo Huang, Weigen Lu*, Jianxin Wang*. A Novel Tumor Targeting Treatment Strategy through Energy Restriction by Co-delivery of Albendazole and Nano-silver. Nano Research, 2018, 1-17; DOI: 10.1007/s12274-018-2032-x.
2. Chengli Ling, Jianming Liang, Chun Zhang, Ruixiang Li, Qianqian Mou, Jin Qin, Xiaofang Li* and Jianxin Wang*. Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury. Molecules 2018, 23(3), 564; doi:10.3390/molecules23030564
3. Ruixiang Li, YuweiHe, ShuyaZhang, JingQin, Jianxin Wang*. Cell membrane based nanoparticles: anew biomimetic platform fortumor diagnosis and treatment. Acta Pharmaceutica Sinica B, 2018;8(1):14–22
4. Ruixiang Li, Jianming Liang, Yuwei He, Jing Qin, Huining He, Seungjin Lee, Zhiqing Pang* and Jianxin*. Sustained Release of Immunosuppressant by Nanoparticle-anchoring Hydrogel Scaffold Improved the Survival of Transplanted Stem Cells and Tissue Regeneration. Theranostics, 2018; 8(4): 878-893
5. Yisi Tang, Jianming Liang, Aihua Wu, Yingzhi Chen, Pengfei Zhao, Tingting Lin, Meng Zhang, Qin Xu, Jianxin Wang* and Yongzhuo Huang*. Co-Delivery of Trichosanthin and Albendazole by Nano-Self- Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis. ACS Appl Mater Interfaces 2017, 9(32):26648-26664
6. Chun Zhang, Chengli Ling, Liang Pang, Qi Wang, Jingxin Liu, Bingshan Wang, Jianming Liang, Jing Qin*, Jianxin Wang*. Direct macromolecular drug to cerebral ischemia area using Neutrophil mediated nanoparticles. Theranostics, 2017,7(13):3260-3275
7. Ruixiang Li, Zhiqing Pang, Huining He, Seungjin Lee, Jing Qin, Jian Wu, Liang Pang, Jianxin Wang*, Victor C. Yang*. Drug depot-anchoring hydrogel: A self-assembling scaffold for localized drug release and enhanced stem cell differentiation. Journal of Controlled Release, 2017, 261:234-245
8. Ziqing Duan, Cuitian Chen, Jing Qin, Qi Liu, Qi Wang, Xinchun Xu*, Jianxin Wang*. Cell-penetrating peptide conjugates to enhance the antitumor effect of paclitaxel on drug-resistant lung cancer. Drug Delivery, 2017, 24(1):752-764
9. Cuitian Chen, Ziqing Duan, Ruixiang Li, Liang Pang, Yan Yuan, Jianming Liang, Xinchun Xu* and Jianxin Wang*. Peptide-22 and cyclic RGD functionalized liposomes for glioma targeting drug delivery overcoming BBB and BBTB. ACS Appl Mater Interfaces. 2017, 9:5864-5873
10. Liang Pang, Chun Zhang, Jing Qin, Limei Han, Ruixiang Li, Huining He and Jianxin Wang*. A novel strategy to achieve effective drug delivery: exploit cells as carrier combined with nanoparticles. Drug Delivery, 2017; 24(1): 83–91
11. Sheng Jianyong, He Huining, Han Limei, Qin Jing, Chen Sunhui, Ru Ge, Li Ruixiang, Yang Pei, Jianxin Wang* and Victor C. Yang*. Enhancing Insulin Oral Absorption by Using Mucoadhesive Nanoparticles Loaded with LMWP-linked Insulin Conjugates. Journal of Controlled Release, 2016, 233:181-190
12. Ru Ge, Han Limei, Qing Jin, Sheng Jianyong, Li Ruixiang, Qiu Mingfeng and Wang Jianxin*. Effects of borneol on the pharmacokinetics of 9-nitrocamptothecin encapsulated in PLGA nanoparticles with different size via oral administration. Drug Delivery. 2016; 23(9): 3417–3423
13. Pang Liang, Qin Jing, Han Limei, Zhao Wenjie, Liang Jianming, Xie Zhongyi, Yang Pei, Pan Yue and Wang Jianxin*. Exploiting macrophages as targeted carrier to guide nanoparticles into glioma. Oncotarget. 2016;7(24):37081-37091
14. Sheng Jianyong, Han Limei, Qin Jing, Ru Ge, Li Ruixiang, Wu Lihong, Cui Dongqi, Yang Pei, He Yuwei, Wang Jianxin*. N-Trimethyl Chitosan Chloride-Coated PLGA Nanoparticles Overcoming Multiple Barriers to Oral Insulin Absorption. ACS Appl Mater Interfaces. 2015, (28) 7:15430-41
15. Jing Qin，Xu Yang，Ruo-Xi Zhang，Yi-Xiao Luo，Jia-Li Li，Jia Hou，Chun Zhang，Yong-Ji Li，Jie Shi，Lin Lu，Jian-Xin Wang*，Wei-Li Zhu*. Monocyte mediated brain targeting delivery of macromolecular drug for the therapy of depression.，Nanomedicine: Nanotechnology, Biology and Medicine，2015,11(2):391-400
16. Limei Han, Qiushi Yang, Teng Shen, Jin Qing, Jianxin Wang*. Lymphatic transport of orally administered probucol-loaded mPEG-DSPE micelles. Drug Delivery, 2015:25:1-7
17. Liu, Ergang，Sheng, Jianyong，Ye, Junxiao，Wang, Yaping，Gong, Junbo，Yang, Victor C.，Wang, Jianxin*，He, Huining. CPP Mediated Insulin Delivery: Current Status and Promising Future，Current Pharmaceutical Biotechnology，2014，15(3): 240-255
18. Lin Zhang, Limei Han, Jing Qin, Weiyue Lu and Jianxin Wang*. Borneol as an Enhancer for Targeting Aprotinin-Conjugated PEG-PLGA Nanoparticles to the Brain. Pharmaceutical research, 2013, 30(10) : 2560-72
19. He, Huining; Sheng, Jianyong; David, Allan E; Kwon, Young Min ; Zhang, Jian; Huang, Yongzhuo; Wang, Jianxin*; Yang, Victor C*. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption. Biomaterials, 2013, 34(31):7733-7743
20. Shen Ming, Huang Yongzhuo, Han Limei, Qin Jing, Fang Xiaoling, Wang Jianxin*. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment. Journal of Controlled Release, 2012, 161：884-892
