Dr. Rongqin Huang received her Ph.D. degree in 2008 in School of Pharmacy, Fudan University. In 2011, she was promoted as Associate Professor in Fudan University. Till now, she has published 46 peer-reviewed papers with SCI he-citation more than 1200, including 10 corresponding authored papers with average impact factor 8.4. And also, she has applied 15 patents, 3 of which were authorized successfully. She has won the Merck-Fudan Scholarship for Excellent Young Teachers, the Excellent Teaching Award sponsored by Gang’ai, the Teaching Award of Daiichi Sankyo Pharmaceutical, and nominated as National Excellent Doctoral Dissertation Award, etc. Rongqin Huang’s researches are funded by NSFC, Sino-German Research Program, Chenguang Talent Plan of Shanghai, Zhuoxue Talent Plan of Fudan, etc. She is also editorial board member of Pharmaceutical Studies and SAJ Pharmacy and Pharmacology. Her researches focus on targeted delivery for combined tumor theragnosis.
Targeted drug delivery; Biomaterials; Blood-brain barrier; Theranostics
Education
2003-2008 Ph. D. in Pharmaceutics, School of Pharmacy, Fudan University
1999-2003 B.S. in Pharmacy, School of Pharmacy, Fudan University
Professional Experiences
2019.12- Professor in Pharmaceutics, School of Pharmacy, Fudan University
2017-2019 Fixed Prof. in Pharmaceutics, School of Pharmacy, Fudan University
2011-2017 Associate Prof. in Pharmaceutics, School of Pharmacy, Fudan University
2015-2016 Visiting Scholar in Department of Bioengineering, UC Berkeley
2010 Post-doctoral Scholar in School of Pharmacy, Munich University, Germany
2008-2011 Assistant Prof. in Pharmaceutics, School of Pharmacy, Fudan University
Teaching Activities
“Drug Delivery materials”, “Brain Health and Science”, “Pharmaceutics”, etc.
Grants & Projects
2017-2019, A biosensor for early diagnosis of pancreatic cancer (“Pu Jiang” project supported by Shanghai Government, principal investigator);
2016-2019, Visualized cascade-targeting micelle for combined glioma therapy (the grant from National Natural Science Foundation of China, principal investigator);
2014-2017, Novel peptide-modified precise oligomers for cascade-targeting gene therapy of glioma (Sino-German research project, principal investigator);
2014-2016, Multifunctional nano-scaled systems for synergistic targeted glioma therapy (Cooperation project with Nantong University, principal investigator);
2013-2017, Studies on novel nanodrugs for brain tumors (supported by the grant from National Key Basic Research Program of China (973 Program), participant);
2013-2014, Multi-mode construction of the course “Brain Health and Science (Fudan University, principal investigator);
2012-2014, Glioma-targeting drug delivery (“Zhuo Xue” Talent Plan of Fudan University, principal investigator);
2012-2013, Glioma-targeting drug delivery system based on mesoporous slilica-graphene nanosheets (supported by grant from State Key Laboratory of Molecular Engineering of Polymers of Fudan University, principal investigator);
2011-2013, Cell-penetrating peptide-modified gene delivery system and its anti-tumor studies (“Chen Guang” project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation, principal investigator);
2010-2012, Construction and mechanism studies of T7-modified glioma-targeted double-loaded nano-scaled delivery system (the grant from National Natural Science Foundation of China, principal investigator);
2010-2012, Mechanisms and anti-parkinsonian studies of Angiopep-modified nano-scaled gene delivery system (the grant from Specialized Research Fund for Doctoral Program, principal investigator).
Awards & Honors
2017, “Pu Jiang” Talent Plan of Shanghai
2016, second prize of excellent paper on the thirteenth meeting of China Youth Pharmaceutical Research Communication
2014, “Merck-Fudan Scholarship for Excellent Young Teachers”
2012, “Gang’ai Scholarship for Outstanding Teachers”
2012, “Zhuo Xue” Talent Plan of Fudan University
2011, “Chen Guang” Talent Plan of Shanghai
2011, the Teaching Award of Daiichi Sankyo Pharmaceutical
2011, the first grade prize in Excellent Achievement of Scientific Researches by Education Ministry (rank 6)
2010, the second grade prize in Shanghai Science-Technology Award (rank 5)
2010, nominated as National Excellent Doctoral Dissertation Award
2009, Shanghai Excellent Doctoral Dissertation Award
2008, the first grade prize in Doctoral Forum of Pharmacy in China
Memberships
Member of the standing committee of Shanghai Healthcare Youth Federation (2018-)
Editorial board member, Journal of Gene Medicine (2017-)
Editorial board member, Nanomedicine and Nanoscience Research (2017-)
Editorial board member, International journal of Pharmaceutical Sciences Research (2016-)
Member of Shanghai Young Scientific and Technological Talent Association (2016-)
Expert for Science and Technology Fund in Pudong New District in Shanghai (2015-)
Invited membership of American Chemical Society (ACS) (2015-)
Editorial board member, Pharmaceutical Studies (2015-)
Editorial board member, SAJ Pharmacy and Pharmacology (2014-)
Senior member of Chinese Pharmaceutical Association (2011-)
Member of Shanghai Pharmaceutical Association (2008-)
Member of Red Cross Society of China (1999-)
Invited Presentations
2018 Sino-German Young Researcher Workshop (Co-organizer), Munich, Germany
2017 Chinese Pharmaceutical Conference, Shanghai, China
2017 Chinese Biomaterial Conference, Nanchang, China
2017 Queenstown Molecular Biology Meeting, Shanghai, China
2016 The 2nd LMU-ChAN SCIENTIFIC FORUM, Hangzhou, China
2016 13th Meeting of China Youth Pharmaceutical Research Communication, Nanchang, China
2015 The 2nd LMU-ChAN SCIENTIFIC FORUM, Munich, Germany
2014 Lindau Life Science Forum, Beijing, China
Selected Publications（latest 5 yrs，<20 papers）
1. Qian M, Du YL, Wang SS, Li CY, Jiang HL, Shi W, Chen J, Wang Y*, Wagner E, Huang RQ*. Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma. ACS Appl Mater Interfaces. 2018, 10(4):4031-40.
2. Wang SS, Li CY, Qian M, Jiang HL, Shi W, Chen J, L?chelt U, Wagner E, Lu WY, Wang Y*, Huang RQ*. Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots. Biomaterials. 2017, 141:29-39.
3. Li CY, Qian M, Wang SS, Jiang HL, Du YL, Wang JX, Lu WY, Murthy N, Huang RQ*. Aptavalve-gated Mesoporous Carbon Nanospheres image Cellular Mucin and provide On-demand Targeted Drug Delivery. Theranostics. 2017, 7(13):3319-25.
4. Shi JL, Hou SQ, Huang JF, Wang SS, Huan W, Huang CJ, Liu XJ, Jiang R, Qian WB, Lu JJ, Wang XB, Shi W*, Huang RQ*, Chen J*. MSN-PEG-IP drug delivery system and IL13 Ra2 for targeted therapy for glioma. Nanoscale. 2017, 9(26):8970-81.
5. Wang SS, Reinhard S, Li CY, Qian M, Jiang HL, Du YL, L?chelt U, Wagner E*, Huang RQ*. Antitumoral cascade-targeting ligand for IL-6 receptor-mediated gene delivery to glioma. Mol Ther, 2017, 25(7):1556-66.
6. Wang Y, Shi W, Wang SS, Li CY, Qian M, Chen J*, Huang RQ*. Facile Incorporation of dispersed Fluorescent Carbon Nanodots into Mesoporous Silica Nanosphere for pH-triggered Drug Delivery and Imaging. 2016, Carbon, 108:146-53.
7. Wang Y, Wang SS, Li CY, Qian M, Bu J, Wang JX, Huang RQ*. Facile Growth of Well-dispersed and Ultra-small MoS2 Nanodots in Ordered Mesoporous Silica Nanoparticles. Chem Commun, 2016, 52(67):10217-20.
8. Meng Y, Wang SS, Li CY, Qian M, Yan XY, Yao SC, Peng XY, Wang Y*, Huang RQ*. Photothermal combined gene therapy achieved by polyethyleneimine-grafted oxidized mesoporous carbon nanospheres. Biomaterials, 2016, 100:134-42.
9. Meng Y, Wang SS, Li CY, Qian M, Zheng YF, Yan XY, Huang RQ*. TKD peptide as a ligand targeting drug delivery systems to memHsp70-positive breast cancer. Int J Pharm. 2016, 498(1-2):40-8.
10. Wang SS, Meng Y, Li CY, Qian M, Huang RQ*. Receptor-Mediated Drug Delivery Systems Targeting to Glioma. Nanomaterials. 2016, 6(1):3-19.
11. Li CY, Meng Y, Wang SS, Qian M, Wang JX, Lu WY, Huang RQ*. Mesoporous Carbon Nanospheres Featured Fluorescent Aptasensor for Multiple Diagnosis of Cancer in Vitro and in Vivo. ACS Nano. 2015, 9(12):12096-103.
12. Yao H, Wang KY, Wang Y, Wang SS, Li JF, Lou JN, Ye LY, Yan XY, Lu WY, Huang RQ*. Enhanced blood-brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system. Biomaterials. 2015, 37:345-52.
13. Wang Y, Meng Y, Wang SS, Li CY, Shi W, Chen J, Wang JX, Huang RQ*. Direct solvent-derived polymer-coated nitrogen-doped carbon nanodots with high water solubility for targeted fluorescence imaging of glioma. Small. 2015, 11(29):3575-81.
14. Wang KY, Yao H, Meng Y, Wang Y*, Yan XY*, Huang RQ*. Specific aptamer-conjugated mesoporous silica-carbon nanoparticles for HER2-targeted chemo-photothermal combined therapy. Acta Biomater. 2015, 16:196-205.
15. Wang Y, Wang KY, Zhang R, Liu XG, Yan XY, Wang JX, Wagner E, Huang RQ*. Synthesis of core-shell graphitic carbon@silica nanospheres with dual-ordered mesopores for cancer-targeted photothermochemotherapy. ACS Nano. 2014, 8(8):7870-9.
16. Wang Y#, Huang RQ#, Liang GH, Zhang ZY, Zhang P, Yu SN, Kong JL*. MRI-visualized, dual-targeting and combined tumor therapy using magnetic graphene-based mesoporous silica. Small. 2014, 10(1):109-16.
17. Wang Y, Wang KY, Yan XY, Huang RQ*. A general strategy for dual-triggered combined tumor therapy based on template semi-graphitized mesoporous silica nanoparticles. Adv. Healthc. Mater. 2014, 3(4):485-9.
18. Wang Y, Wang KY, Zhao JF, Liu XG, Bu J, Yan XY, Huang RQ*. Multifunctional mesoporous silica-coated graphene nanosheet used for chemo-photothermal synergistic targeted therapy of glioma. J. Am. Chem. Soc. 2013, 135(12):4799-804.
19. Huang RQ#, Ma HJ#, Guo YB, Liu SH, Kuang YY, Shao K, Li JF, Liu Y, Han L, Huang SX, An S, Ye LY, Lou JN, Jiang C. Angiopep-conjugated nanoparticles for targeted long-term gene therapy of Parkinson’s Disease. Pharm Res. 2013, 30(10):2549-59.
Patents
Till now, 19 patents have been applied, 3 of which successfully issued.
