Dr. Jianping Qi got his Ph.D degree from China Pharmaceutical University in 2009, majored in Pharmaceutics. And then, he joined department of pharmaceutics of school of pharmacy in Fudan University as a lecturer. He promoted to associate professor of pharmaceutical sciences in 2014 and did exchange research for one year in department of chemical engineering of University of California at Santa Barbara in 2015. His research interests are developing new strategies for improving oral bioavailability of poorly water soluble drugs and proteins or peptides, and design and in vivo evaluation of nano drug delivery systems. He has published 60 research articles in SCI index and been funded by Shanghai Committee of Science and Technology and National Natural Science Foundation of China.
Oral delivery; Transdermal delivery; Nanoparticles; Liposomes; Absorption mechanisms
Education
Ph.D. Sep. 2004-Jul. 2009, China Pharmaceutical University, Pharmaceutical Sciences, Nanjing, P.R. China
B.S. Sep. 2000-Jul. 2004, China Pharmaceutical University, Pharmaceutical Engineering, Nanjing, P.R. China
Professional Experiences
Dec. 2014-Present, Associate Professor, Department of Pharmaceutics, Fudan University
Mar. 2015-Mar. 2016, Visiting Scholar, Department of Chemical Engineering, University of California at Santa Barbara
Jul. 2009-Dec. 2014, Lecturer, Department of Pharmaceutics, Fudan University
Teaching Activities
Undergraduate students: Pharmaceutics, Biopharmaceutics and Pharmacokinetics
Graduate students: Experimental design, Industrial pharmacy, Cutting edge of pharmaceutics
Grants & Projects
1. PI, Study on targeting inflammatory bowel diseases by oral pH sensitive rod shaped nanocarriers (18ZR1404100), Shanghai Natural Science Foundation, 2018.6-2021.5.
2. PI, Study on traffic mechanisms of liposomes in gastrointestinal tract based on FRET effect (15ZR1403000), Shanghai Natural Science Foundation, 2015.1-2017.12
3. PI, Controlled release of “solid lipid nanoparticles” as an integral unit (81001405), National Natural Science Foundation of China, 2011.1-2013.12
4. PI, Improving oral bioavailability of proteins by nanoemulsions coated with alginate-chitosan (1052nm03600), Shanghai Municipal Committee of Science and Technology, 2010.3-2012.6
5. PI, Casein nanoparticle improving oral absorption of insoluble drugs, Shanghai Municipal Healthy Bureau, 2013.1-2015.12.
6. PI, Funding of Young Scientists of School of Pharmacy, Fudan University
7. PI, Funding of Young Scientists of Fudan University
Awards & Honors
2017. Dechuan Healthcare Awards of Fudan University
2017. First Prize of Teaching Competition in Nationwide Universities related to Pharmacy
2015. Gang’ai Awards of Fudan University
2014. Daiichi-Sankyo Awards of Fudan University
2012. Merck-Fudan Awards for teachers
Memberships
Youth editor,《Chinese Chemical Letters》
Board member, Chapter of Nanobiotechnology, China Medicinal Biotech Association
Selected Publications（latest 5 yrs，<20 papers）
1. Jianping Qi, Jie Zhuang, Yongjiu Lv, Yi Lu, Wei Wu*. Exploiting or overcoming the dome trap for enhanced oral immunization and drug delivery. Journal of Controlled Release 2018; 275: 92-106.
2. Dong Li, Jie Zhuang, Haisheng He, Sifan Jiang, Amrita Banerjee, Yi Lu, Wei Wu, Samir Mitragotri, Li Gan*, Jianping Qi*: Influence of particle geometry on gastrointestinal transit absorption following oral administration. ACS Applied Materials & Interfaces 2017; 9: 42492-42502.
3. Jianping Qi, Jie Zhuang, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu*: In vivo fate of lipid-based nanoparticles. Drug Discovery Today 2017; 22(1): 166-172.
4. Amrita Banerjee1, Jianping Qi1, Rohan Gogoi, Jessica Wong, Samir Mitragotri*: Role of nanoparticle size, shape and surface chemistry in oral drug delivery. Journal of Controlled Release 2016; 238:176-185.
5. Zhiqiang Tian, Qin Yu, Yunchang Xie, Li Xiang, Fengqian Li, Yi Lu, Xiaochun Dong, Weili Zhao, Jianping Qi*, Wei Wu*: Controlling Release of Integral Lipid Nanoparticles Based on Osmotic Pump Technology. Pharmaceutical Research 2016; 33(8):1988-1997.
6. Meng Cui, Wei Wu, Lars Hovgaard, Yi Lu, Dawei Chen*, Jianping Qi*: Liposomes containing cholesterol analogues of botanical origin as drug delivery systems to enhance the oral absorption of insulin. International Journal of Pharmaceutics 2015; 489(1-2):277-284.
7. Jianping Qi, Yi Lu, Wei Wu*: Manufacturing Solid Dosage Forms from Bulk Liquids Using the Fluid-bed Drying Technology. Current Pharmaceutical Design 2015; 21(19):2668-2676.
8. Kai Wang, Jianping Qi*, Tengfei Weng, Zhiqiang Tian, Yi Lu, Kaili Hu, Zongning Yin*, Wei Wu: Enhancement of oral bioavailability of cyclosporine A: comparison of various nanoscale drug delivery systems. International Journal of Nanomedicine 2014; 9:4991-4999.
9. Tengfei Weng, Jianping Qi*, Yi Lu, Kai Wang, Zhiqiang Tian, Kaili Hu, Zongning Yin, Wei Wu: The role of lipid-based nano delivery systems on oral bioavailability enhancement of fenofibrate, a BCS II drug: comparison with fast-release formulations. Journal of Nanobiotechnology 2014; 12(1).
10. Xingwang Zhang, Jianping Qi*, Yi Lu, Xiongwei Hu, Wei He, Wei Wu: Enhanced hypoglycemic effect of biotin-modified liposomes loading insulin: effect of formulation variables, intracellular trafficking, and cytotoxicity. Nanoscale Research Letters 2014; 9(1):185.
11. Xi Zhang, Yueneng Yi, Jianping Qi*, Yi Lu, Zhiqiang Tian, Yunchang Xie, Fuqiang Hu, Hailong Yuan, Wei Wu*: Controlled release of self-nanoemulsifying systems from osmotic pump tablets: near zero-order release in vitro and pharmacokinetics in dogs. International Journal of Pharmaceutics 2013; 452:233-240.
12. Zhiqiang Tian, Jianping Qi*, Yueneng Yi, Jin Han, Hailong Yuan, Xi Zhang, Yunchang Xie, Fuqiang Hu, Yi Lu, Wei Wu*: Solidification of nanostructured lipid carriers (NLCs) onto pellets by fluid-bed coating: Preparation, in vitro characterization and bioavailability in dogs. Powder Technology 2013; 247:120-127.
13. Yikang Dai, Rui Zhou, Lin Liu, Yi Lu, Jianping Qi*, Wei Wu: Liposomes containing bile salts as novel ocular delivery systems for tacrolimus (FK506): In vitro characterization and improved corneal permeation. International Journal of Nanomedicine 2013; 8:1921-1933.
14. Jianping Qi, Yi Lu, Wei Wu*: Application of Lipid Nanoparticles as Oral Drug Delivery System. Progress in Biochemistry and Biophysics 2013; 40(10):1008-1013.
15. Xiaoyang Li, Jianping Qi*, Yunchang Xie, Xi Zhang, Shunwen Hu, Ying Xu, Yi Lu, Wei Wu*: Nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: Preparation, characterization, and hypoglycemic effect in rats. International Journal of Nanomedicine 2013; 8:23-32.
16. Ya'nan Tan, Jianping Qi*, Yi Lu, Fuqiang Hu, Zongning Yin, Wei Wu: Lecithin in mixed micelles attenuates the cytotoxicity of bile salts in Caco-2 cells. Toxicology in Vitro 2013; 27(2):714-20
