Dr. Zhiqing Pang obtained his Ph.D. from Fudan University in 2008. As a lecturer in School of Pharmacy, Fudan University, he was granted 3 projects from NCFC and Ministry of Education. He has published 25 high-impact SCI papers and 3 book chapters. He also has 3 issued patents worldwide and 1 native clinical trial permission. He won 1 1st Award for Natural Sciences of Ministry of Education. He is also the invited reviewer of some leading journals such as ACS nano, Biomaterials, Theranostics, and Nanoscale.
Targeting drug delivery systems; Nanoantidotes; Development of novel formulations
Education
2005.9-2008.6 Ph.D., Pharmaceutics, Fudan University, PR China,
2000.9-2003.6 M.A., Pharmaceutics, Sun Yat-Sen University, PR China,
1996.9-2000.6 B.A., Biology, South China Normal University, PR China,
Professional Experiences
2016.12-now Associate Researcher, Fudan University, PR China
2014.1-2015.1 Visiting scholar, University of California, San Diego, USA
2008.7-2016.10 Assistant Professor, Fudan University, PR China
2003.7-2005.8 Project manager, Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Limited, PR China
Teaching Activities
2009.2-now Pharmacokinetics, undergraduate curriculum
2011.2-now Targeting drug delivery systems, graduate curriculum
2013.9-now Nanomedicine and health undergraduate curriculum
Grants & Projects
Director, National Natural Science Foundation of China 81773283 (2018-2021)
Director, National Natural Science Foundation of China 81472757 (2015-2018)
Director, National Natural Science Foundation of China 81001404 (2011-2013)
Director, The Doctoral Fund of Ministry of Education of China 20100071120050 (2011-2013)
Director, Talent Teacher Program of Fudan University (2012)
Awards & Honors
ACPS- Sanofi Biotherapeutics Young Scientist Award (2017)
Fudan University & Merk Award for Excellent Teachers (2011)
Excellent Presentation Award of Annual Meeting of ACPS (Tianjin, 2011)
The 1st Prize of Natural Science by Chinese Ministry of Education 2010-015 (2010)
Excellent Presentation Award of Doctoral Forum of China (Pharmacy, Shanghai, 2008)
Excellent Presentation Award of the 4th National Pharmaceutical Forum of China (Shanghai, 2009)
Invited Presentations
1. Z. Pang, Modulating the tumor microenvironment to enhance tumor nanomedicine delivery. The 2nd international symposium of Biotherapuetics Delivery Society (Soul, Korea, 2017)
2. Z. Pang, Targeting chemotherapy for glioma rats by transferrin-conjugated biodegradable polymersomes. Annual Meeting of Association of Chinese Pharmaceutical Science (Tianjin, China, 2011)
3. Z. Pang, Enhanced intracellular delivery and chemotherapy for glioma rats by transferrin-conjugated biodegradable polymersomes loaded with doxorubicin. The 4th National Pharmaceutical Forum of China (Shanghai, China, 2009)
4. Z. Pang, Brain delivery of cationic albumin conjugated nanoparticles. Doctoral Forum of China (Pharmacy section, Shanghai, China, 2008)
Selected Publications（latest 5 yrs，<20 papers）
1. Y. Song, Z. Huang, J. Xu, D. Ren, Y. Wang, X. Zheng, Y. Shen, L. Wang, H. Gao, J. Hou, Z. Pang*, J. Qian*, J. Ge*, Multimodal SPION-CREKA peptide based agents for molecular imaging of microthrombus in a rat myocardial ischemia-reperfusion model, Biomaterials, 35 (2013) 2961-2970.
2. B. Zhang, X. Sun, H. Mei, Y. Wang, Z. Liao, J. Chen, Q. Zhang, Y. Hu*, Z. Pang*, X. Jiang, LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma, Biomaterials, 34 (2013) 9171-9182.
3. H. Gao, S. Zhang, Z. Yang, S. Cao, X. Jiang, Z. Pang*, In vitro and in vivo intracellular distribution and anti-glioblastoma effects of docetaxel-loaded nanoparticles functioned with IL-13 peptide, International Journal of Pharmaceutics, 466 (2014) 8-17.
4. Y. Yu, X. Jiang, S. Gong, L. Feng, Y. Zhong*, Z. Pang*, The proton permeability of self-assembled polymersomes and their neuroprotection by enhancing a neuroprotective peptide across the blood-brain barrier after modification with lactoferrin, Nanoscale, 6 (2014) 3250-3258.
5. B. Zhang, S. Shen, Z. Liao, W. Shi, Y. Wang, J. Zhao, Y. Hu, J. Yang, J. Chen, H. Mei, Y. Hu*, Z. Pang*, X. Jiang, Targeting fibronectins of glioma extracellular matrix by CLT1 peptide-conjugated nanoparticles, Biomaterials, 35 (2014) 4088-4098.
6. B. Zhang, H. Wang, Z. Liao, Y. Wang, Y. Hu, J. Yang, S. Shen, J. Chen, H. Mei, W. Shi, Y. Hu*, Z. Pang*, X. Jiang, EGFP-EGF1-conjugated nanoparticles for targeting both neovascular and glioma cells in therapy of brain glioma, Biomaterials, 35 (2014) 4133-4145.
7. Z. Pang, C.M. Hu, R.H. Fang, B.T. Luk, W. Gao, F. Wang, E. Chuluun, P. Angsantikul, S. Thamphiwatana, W. Lu, X. Jiang, L. Zhang*, Detoxification of Organophosphate Poisoning Using Nanoparticle Bioscavengers, ACS Nano, 9 (2015) 6450-6458.
8. B. Zhang, Y. Zhang, Z. Liao, T. Jiang, J. Zhao, Y. Tuo, X. She, S. Shen, J. Chen, Q. Zhang, X. Jiang, Y. Hu*, Z. Pang*, UPA-sensitive ACPP-conjugated nanoparticles for multi-targeting therapy of brain glioma, Biomaterials, 36 (2015) 98-109.
9. X. Yu, J. Wang, J. Liu, S. Shen, Z. Cao, J. Pan, S. Zhou, Z. Pang*, D. Geng*, J. Zhang*, A multimodal Pepstatin A peptide-based nanoagent for the molecular imaging of P-glycoprotein in the brains of epilepsy rats, Biomaterials, 76 (2016) 173-186.
10. B. Zhang, T. Jiang, L. Ling, Z. Cao, J. Zhao, Y. Tuo, X. She, S. Shen, X. Jiang, Y. Hu*, Z. Pang*, Enhanced Antitumor Activity of EGFP-EGF1-Conjugated Nanoparticles by a Multitargeting Strategy, ACS Appl Mater Interfaces, 8 (2016) 8918-8927.
11. B. Zhang, T. Jiang, X. She, S. Shen, S. Wang, J. Deng, W. Shi, H. Mei, Y. Hu*, Z. Pang*, X. Jiang, Fibrin degradation by rtPA enhances the delivery of nanotherapeutics to A549 tumors in nude mice, Biomaterials, 96 (2016) 63-71.
12. B. Zhang, T. Jiang, S. Shen, X. She, Y. Tuo, Y. Hu*, Z. Pang*, X. Jiang, Cyclopamine disrupts tumor extracellular matrix and improves the distribution and efficacy of nanotherapeutics in pancreatic cancer, Biomaterials, 103 (2016) 12-21.
13. B. Zhang, H. Wang, S. Shen, X. She, W. Shi, J. Chen, Q. Zhang, Y. Hu*, Z. Pang*, X. Jiang, Fibrin-targeting peptide CREKA-conjugated multi-walled carbon nanotubes for self-amplified photothermal therapy of tumor, Biomaterials, 79 (2016) 46-55.
14. Q. Jiang, Z. Luo, Y. Men, P. Yang, H. Peng, R. Guo, Y. Tian, Z. Pang*, W. Yang*, Red blood cell membrane-camouflaged melanin nanoparticles for enhanced photothermal therapy, Biomaterials, 143 (2017) 29-45.
15. T. Jiang, B. Zhang, S. Shen, Y. Tuo, Z. Luo, Y. Hu*, Z. Pang*, X. Jiang, Tumor Microenvironment Modulation by Cyclopamine Improved Photothermal Therapy of Biomimetic Gold Nanorods for Pancreatic Ductal Adenocarcinomas, ACS Appl Mater Interfaces, 9 (2017) 31497-31508.
16. R. Li, Z. Pang, H. He, S. Lee, J. Qin, J. Wu, L. Pang, J. Wang*, V.C. Yang*, Drug depot-anchoring hydrogel: A self-assembling scaffold for localized drug release and enhanced stem cell differentiation, J Control Release, 261 (2017) 234-245.
17. Z. Luo, K. Jin, Q. Pang, S. Shen, Z. Yan, T. Jiang, X. Zhu, L. Yu*, Z. Pang*, X. Jiang, On-Demand Drug Release from Dual-Targeting Small Nanoparticles Triggered by High-Intensity Focused Ultrasound Enhanced Glioblastoma-Targeting Therapy, ACS Appl Mater Interfaces, 9 (2017) 31612-31625.
18. X. Wang, H. Li, X. Liu, Y. Tian, H. Guo, T. Jiang, Z. Luo, K. Jin, X. Kuai, Y. Liu, Z. Pang*, W. Yang*, S. Shen*, Enhanced photothermal therapy of biomimetic polypyrrole nanoparticles through improving blood flow perfusion, Biomaterials, 143 (2017) 130-141.
19. B. Zhang, T. Jiang, Y. Tuo, K. Jin, Z. Luo, W. Shi, H. Mei, Y. Hu*, Z. Pang*, X. Jiang, Captopril improves tumor nanomedicine delivery by increasing tumor blood perfusion and enlarging endothelial gaps in tumor blood vessels, Cancer Lett, 410 (2017) 12-19.
20. R. Li, J. Liang, Y. He, J. Qin, H. He, S. Lee, Z. Pang*, J. Wang*, Sustained Release of Immunosuppressant by Nanoparticle-anchoring Hydrogel Scaffold Improved the Survival of Transplanted Stem Cells and Tissue Regeneration, Theranostics, 8 (2018) 878-893.
Patents
1. L. Zhang, Z. Pang, R. Fang, J. Hu, Detoxification Using Nanoparticles .PCT WO2016-176041.
2. Z. Pang, et al. A nanoparticulate drug delivery system targeting to glioma. Chinese Patent, Chinese Patent No: 201210306978.1
3. H. Gao, Z. Pang, X. Jiang. Preparation and application of cascade targeting drug delivery systems for brain diseases. Chinese Patent No: 201110315516.1
4. H. Gao, X. Jiang, Z. Pang. Paclitaxel-loaded albumin nanoparticles injection and its preparation method. Chinese Patent No: 201210301743.3
5. D. Yang, F. Wang, Z. Pang, Y. Wang. A new isolation and purification method of capsaicin by macroporous resins. Chinese Patent NO: 02134384.5
6. D. Yang, D. Wang, Z. Pang, F. Wang. A new isolation and purification method of capsaicin by molecular distillation. Chinese Patent NO: 02134386.1
7. D. Yang, Z. Pang, D. Wang. A new extraction and purification method of the natural red chili color. Chinese Patent NO: 02134381.0
