Dr. Jian-Zhong Lu obtained his Ph.D. from Nanjing University in 1995. Thereafter, he studied for a couple of universities abroad. Dr. Lu joined the faculty of Fudan University in 2002 as a professor of Pharmaceutical Analysis. He mainly engaged in graduate teaching and analytical and pharmaceutical analysis related researches. He has been teaching two graduate courses on fluorescence and chemiluminescence in pharmaceutical analysis and already published more than 70 academic papers, where 12 papers were published in the prestigious journal of "Analytical Chemistry".
Nucleic acid analysis; Protein analysis; Chemiluminescence; Fluorescence
Education
1992.9-1995.6 Nanjing University, Department of Chemistry, Ph.D.
1987.9-1990.6 Lanzhou University, Department of Chemistry, MS.
1983.9-1987.6 Lanzhou University, Department of Chemistry, BS.
Professional Experiences
2002.8-present Fudan University, School of Pharmacy, Professor.
2001.2-2002.8 Nagasaki University, School of Pharmacy, JSPS fellow.
1999.8-200.8 University of New Orleans, Department of Chemistry, Postdoc.
1998.5-1999.5 ETH, Department of Chemistry, Simon fellow.
1997.4-1998.4 Hong Kong Baptist University, Visiting Scholar.
1995.8-1997.4 Xiamen University, Department of Chemistry, Postdoc.
Selected Publications
1. Tian, Xiaodong; Liu, Xinda; Wang, Anni; Lau, Choiwan; Lu, Jianzhong*, Bioluminescence imaging of carbon monoxide in living cells and nude mice based on Pd0-mediated Tsuji-Trost reaction, Anal. Chem., DOI: 10.1021/acs.analchem.8b01102.
2. Li, Zhiyan; Lau, Choiwan; Lu, Jianzhong*, Effect of the concentration difference between magnesium ions and total ribonucleotide triphosphates in governing the specificity of T7 RNA polymerase-based rolling circle transcription for quantitative detection, Anal. Chem., 2016, 88, 6078-6083.
3. Tian, Xiaodong; Li, Zhiyan; Lau, Choiwan; Lu, Jianzhong*, Visualization of in vivo hydrogen sulfide production by a bioluminescence probe in cancer cells and nude mice, Anal. Chem., 2015, 87, 11325-11331.
4. Li, Dongbei; Wang, Yinan; Lau, Choiwan*; Lu, Jianzhong*, xMAP array microspheres based stem-loop structured probes as conformational switches for multiplexing detection of miRNAs, Anal. Chem., 2014, 86, 10148-10156.
5. Cai, Sheng; Lao, Kameng; Lau, Choiwan; Lu, Jianzhong*, "Turn-on" chemiluminescence sensor for the highly selective and ultrasensitive detection of Hg2+ ions based on interstrand cooperative coordination and catalytic formation of gold nanoparticles, Anal. Chem., 2011, 83, 9702-9708.
6. Cai, Sheng; Lau, Choiwan; Lu, Jianzhong*, Turn-on aptameric system for simple and selective detection of protein via base stacking-dependent DNA hybridization event, Anal. Chem., 2011, 83, 5844-5850.
7. Cai, Sheng; Lau, Choiwan; Lu, Jianzhong*, Sequence-specific detection of short-length DNA via template-dependent surface-hybridization events, Anal. Chem., 2010, 82, 7178-7184.
8. Miao, Juru; Cao, Zhijuan; Zhou, Yang; Lau, Choiwan; Lu, Jianzhong*, Instantaneous derivatization technology for simultaneous and homogeneous determination of multiple DNA targets, Anal. Chem., 2008, 80, 1606-1613.
9. Zhou, Yang; Zhang, Yuhao; Lau, Choiwan; Lu, Jianzhong*, Sequential determination of two proteins by temperature-triggered homogeneous chemiluminescent immunoassay, Anal. Chem., 2006, 78, 5920-5924.
10. Fan, Aiping; Lau, Choiwan; Lu, Jianzhong*, Magnetic bead-based chemiluminescent metal immunoassay with a colloidal gold label, Anal. Chem., 2005, 77, 3238-3242.
