Gang Chen was born on November 23, 1969. He received his PhD degree in analytical chemistry degree from East China Normal University (Shanghai, China) in 2001. From 2002 to 2003, he worked as a post-doc research fellow in Professor Joseph Wang’s group in New Mexico State University. At present, he is a professor in School of Pharmacy, Fudan University (Shanghai, China). His research interests include electroanalysis, capillary electrophoresis and microfluidic chip. He has published more than 120 papers. A series of novel fabrication approaches have been developed by his group to realize the mass production of microfluidic chips at low cost. The biochips have been successfully applied in pharmaceutical analysis, food monitoring, proteomics, pollutant detection, etc. In addition, a series of analytical techniques based on carbon nanotubes, graphene, and capillary electrophoresis have been developed by Chen’s lab for the rapid analysis and screening of traditional Chinese medicines.
Capillary electrophoresis; Micro & Nano analytical methods; Pharmaceutical analysis
Education
BA in Chemistry, Anhui Normal University, 1992.
MS in Physical Chemistry, East China Normal University, 1995.
PhD in Analytical Chemistry, East China Normal University, 2001.
Professional Experiences
Teaching Assistant and Lecturer, Department of Chemistry, Shanghai Medical University (1995-2001)
Postdoctoral research fellow, Department of Chemistry and Biochemistry, New Mexico State University, USA (2002-2003)
Associate Professor, Department of Chemistry, Fudan University (2002-2007).
Professor, School of Pharmacy, Fudan University (2007-present).
Teaching Activities
1. Physical Chemistry, a compulsory course for undergraduates of pharmacy;
2. Microfluidic technology and its applications, an elective course for graduates of pharmacy.
Awards & Honors
1. Gang Chen, Luyan Zhang, Fabrication of PMMA microchips and theirs biomedical applications, Shanghai Municipal People's Government, Shanghai Technical Invention Award, 3rd grade, 2009.11.23;
2. Gang Chen, Bangguo Wei, Zhi Chen, Electrochemical determination of the bioactive constituents in TCMs based on carbon-based nonmaterials, Shanghai Pharmaceutical Association, Shanghai pharmaceutical science and Technology Award, 2nd grade, 2011.12.24;
3. Gang Chen, Bangguo Wei, Yuejiao Fu, Rapid extraction of bioactive constituennts in TCMs and high effcient proteolysis based on infrared irradiations, Shanghai pharmaceutical science and Technology Award, 3rd grade, 2015.12.20.
Memberships
Member of the Chinese Pharmaceutical Association
Invited Presentations
1. 2016 International Conference on Microfluidic Chips and Micro/Nano Scale Biological Separation and Analysis, Fabrication and modification of polymer microfluidic chips and their application in biomedical analysis, 2016.5.8, Lanzhou.
2. 4th International Conference on Microfluidic Chips and Micro/Nano Scale Biological Separation and Analysis, Carbon nanomaterial-based electrodes for the amperometric detection of capillary and microchip electrophoresis, 2016.5.17, Xiamen.
Selected Publications（latest 5 yrs，<20 papers）
1. Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects, Sijie Lu; Nand R.A.; Yang J.S.; *Gang Chen; Gross A.S.
2. European Journal of Clinical Pharmacology, 74, pp 285-296, 2018.3.1
Simultaneous determination of five bioactive constituents in Rhizoma Chuanxiong by capillary electrophoresis with a carbon nanotube-polydimethylsiloxane composite electrode, Luyan Zhang; Wei Zhang; Weilong Chen; *Gang Chen, Journal of Pharmaceutical and Biomedical Analysis, 131, pp 107-112, 2016.11.30
3. Fabrication of a carbon nanotube-polyurethane composite electrode by in situ polyaddition for use in amperometric detection in capillary electrophoresis, Fenfen Ma; Wei Zhang; Joseph Wang; Luyan Zhang; *Gang Chen, Microchim Acta, 183(9), pp 2579-2587, 2016.9.1
4. Determination of carbohydrates in honey and milk by capillary electrophoresis in combination with graphene-cobalt microsphere hybrid paste electrodes, Peipei Liang; Motao Sun; Peimin He; Luyan Zhang; *Gang Chen, Food Chemistry, 190, pp 64-70, 2016.1.1
5. Preparation of porous graphene oxide-poly(urea-formaldehyde) hybrid monolith for trypsin immobilization and efficient proteolysis, Peipei, Liang; Huimin Bao; Jifang Yang; Luyan Zhang; *Gang Chen, Carbon, 97, pp 25-34, 2016.2
6. Preparation of porous graphene using cuprous oxide microspheres as sacrificial templates for enriching proteins and peptides, Huimin Ge; Huimin Bao; Luyan Zhang; *Gang Chen, Carbon, 82, pp 579-589, 2015.2
7. Assembly of graphene and nickel nanoparticles on anion exchange resin microspheres for the amperometric detection of carbohydrates in combination with capillary electrophoresis, Ren Zhang; Sijie Lu; Luyan Zhang; *Gang Chen, Journal of Chromatography A, 1374, pp 261-267, 2014.12.29
8. Low temperature preparation of a graphene-cobalt microsphere hybrid by borohydride-initiated reduction for enriching proteins and peptides, Huimin Ge; Huimin Bao; Luyan Zhang; *Gang Chen, Journal of Materials Chemistry B, 2(32), pp 5220-5228, 2014.8.28
9. Immobilization of trypsin on miniature incandescent bulbs for infrared-assisted proteolysis, Huimin Ge; Huimin Bao; Luyan Zhang; *Gang Chen, Analytica Chimica Acta, 845, pp 77-84, 2014.10.3
10. Fabrication of carbon nanotube-nickel nanoparticle hybrid paste electrodes for electrochemical sensing of carbohydrates, Wei Zhang; Xia Zhang; Luyan Zhang; *Gang Chen. Sensors and Actuators B: Chemical, 192, pp 459-466, 2014.3
11. Determination of 5,7-dihydroxychromone and luteolin in peanut hulls by capillary electrophoresis with a multiwall carbon nanotube/poly(ethylene terephthalate) composite electrode, Sheng Shijun; Luyan Zhang; *Gang Chen, Food Chemistry, 145, pp 555-561, 2014.1.20
12. Facile preparation of graphene-copper nanoparticle composite by in situ chemical reduction for electrochemical sensing of carbohydrates, Qiwen Chen; Luyan Zhang; *Gang Chen, Analytical Chemistry, 84(1), pp 171-178, 2012.1.2
13. Graphene-epoxy composite electrode fabricated by in situ polycondensation for enhanced amperometric detection in capillary electrophoresis, Dengfeng Tang; Guo Ma; Luyan Zhang; *Gang Chen, Journal of Chromatography A, 1316, pp 127-134, 2013.11.5
14. Immobilization of trypsin via graphene oxide-silica composite for efficient microchip proteolysis, Huimin Bao; Luyan Zhang; *Gang Chen, Journal of Chromatography A, 1310, pp 74-81, 2013.10.4
15. Fabrication of a magnet-assisted alignment device for the amperometric detection of capillary electrophoresis using a carbon nanotube/polypropylene composite electrode, Junchao Xu; Luyan Zhang; *Gang Chen, Electrophoresis, 34(14), pp 2017-2024, 2013.7
16. Fabrication of graphene/poly(ethyl 2-cyanoacrylate) composite electrode for amperometric detection in capillary electrophoresis, Junchao Xu; Luyan Zhang; *Gang Chen, Sensors and Actuators B: Chemical, 182, pp 689-695, 2013.6
17. Facile assembly of graphene on anion exchange resin microspheres for electrochemical sensing and biosensing, Shijun Sheng; Shuang Liu; Luyan Zhang; *Gang Chen, Chemistry-An Asian Journal, 8(1), pp 191-197, 2013.1
18. Efficient proteolysis strategies based on microchip bioreactors, Shuang Liu; Huimin Bao; Luyan Zhang; *Gang Chen, Journal of Proteomics, 82, pp 1-13, 2013.4.26
19. Graphene/poly(ethylene-co-vinyl acetate) composite electrode fabricated by melt compounding for capillary electrophoretic determination of flavones in Cacumen platycladi, Shijun Sheng; Shuang Liu; Luyan Zhang; *Gang Chen, Journal of Separation Science, 36(4), pp 721-728, 2013.2
20. Magnetic loading of graphene-nickel nanoparticle hybrid for electrochemical sensing of carbohydrates, Weidong Qu; Luyan Zhang; *Gang Chen, Biosensors and Bioelectronics, 42, pp 430-433, 2013.4.15
Patents
1. Gang Chen, Luyan Zhang, Shijun Sheng, Preparation of a nickel nanoparticle-carbon nanotube hybridand its application, Chinese patent, Patent No.: ZL201310740834.1；
2. Gang Chen, Bangguo Wei, huimin Bao, Luyan Zhang, Preparation and application of a proteolysis microfluidic chip based on GO-silica composite film, Chinese patent, Patent No.: ZL201210561470.6.
