Yunqiu Yu: Professor Yu graduated from Chemistry Department, East China Normal University in 1986 and joined the faculty of Pharmaceutical Analysis of Shanghai Medical University in the same year. She engaged in analytical chemistry teaching and pharmaceutical analysis related researches, commissioned as editorial board member of multiple versions analytical chemistry textbooks and lectured undergraduate and graduate courses. She published more than 50 academic papers in English or Chinese, accessed to four domestic invention patents, received Shanghai Graduate Students Excellence Achievement Award(advisor)and third prize of Shanghai Science and Technology Progress Award in 2009. She also won Silver award of Shanghai Invention Tryouts in 2011. The main results of her researches include the establishment of in vivo separation and analysis method of small molecule drug recombinant multi-functional Arg-Gly-Asp-hirudin, successfully application of capillary electrophoresis-laser induced fluorescence, and CE-TOF mass spectrometry coupling technique in in vivo toxicological and metabolites analysis studies.
Metabolomics; HPLC&LC-MS; GC&GC-MS; CE&CE-MS
Education
1979-1983 Department of Chemistry, East China Normal University undergraduate student, bachelor degree
1983-1986 Department of Chemistry, East China Normal University, postgraduate student, Master degree
Professional Experiences
Professor Yu graduated from Chemistry Department, East China Normal University in 1986 and joined the faculty of Pharmaceutical Analysis department of Shanghai Medical University in the same year. She engaged in analytical chemistry teaching and pharmaceutical analysis related researches, lectured undergraduate and graduate courses and commissioned as editorial board member of multiple versions of analytical chemistry textbooks. She studies on Metabolomics and specialized in method development and research of in vivo and in vitro pharmaceutical analysis, published more than 50 academic papers, accessed to four domestic invention patents.
Grants & Projects
NSFC:C190703(2009-2011), 81272988(2013.1-2013.12), 81773325(2018-2021)
Shanghai Municipal Natural Science Foundation:03ZR14010 (2010)
Awards & Honors
A third-class prize from shanghai government (Capillary electrophoresis for the analysis of illicit drugs)
Excellent invention (silver award) of Shanghai excellent invention competition
Shanghai graduate outstanding achievement award (academic dissertation, supervisor)
Selected Publications(latest 5 yrs,<20 papers)
1. Guoting Jiang, Xiaoyan Shen, Hongyan Kang, Kejia Li, Jie Zheng*, Yunqiu Yu*. Serum metabolite profiling of cutaneous T-cell lymphoma based on a multiplatform approach. Journal of Chromatography B[J]. 2018, 1077-1078: 71-6.
2. Yunchen Le, Xiaoyan Shen, Hongyan Kang, Qizheng Wang, Kejia Li, Jie Zheng*, Yunqiu Yu*. Accelerated, untargeted metabolomics analysis of cutaneous T-cell lymphoma reveals metabolic shifts in plasma and tumor adjacent skins of xenograft mice. Journal of Mass Spectrometry[J]. 2018, 53(2): 172-82.
3. Guoting Jiang, Hongyan Kang, Yunqiu Yu*. Cross-platform metabolomics investigating the intracellular metabolic alterations of HaCaT cells exposed to phenanthrene. Journal of Chromatography B[J]. 2017, 1060: 15-21.
4. Hongyan Kang, Xia Li, Qingyuan Zhou, Chen Quan, Feng Xue, Jie Zheng*, Yunqiu Yu*. Exploration of candidate biomarkers for human psoriasis based on gas chromatography-mass spectrometry serum metabolomics. British Journal of Dermatology[J]. 2017, 176: 713–22.
5. Xia Li, Yu Wang, Qingyuan Zhou, Yunqiu Yu*, Lihong Chen, Jie Zheng. A sensitive method for digoxin determination using formate-adduct ion based on the effect of ionization enhancement in liquid chromatograph-mass spectrometer. Journal of Chromatography B[J]. 2015, 978-979: 138-44.
6. Qingyuan Zhou, Yuelin Wang, Xia Li, Xiaoyan Shen, Kejia Li, Jie Zheng, Yunqiu Yu*. Metabolics Investigation of Cutaneous T Cell Lymphpma Based on UHPLC-QTOF/MS. Asian Pacific journal of cancer prevention[J]. 2014, 15(13): 5417-21.
7. Xiaoyun Liu, Shuiqing Zheng, Zheng Jiang, Chen Liang, Rong Wang, Zhe Zhou, Yurong Zhang, Yunqiu Yu*. Rapid separation and identification of Strychnos alkaloids metabolites in rats by ultra high performance liquid chromatography with linear ion trap Orbitrap mass spectrometry. Journal of Separation Science[J]. 2014, 37(7): 764–74.
8. Qixin Dong,Jiajun Zhu,Qiang Sui,Chao Tang,Xiaomei Wang,Yunqiu Yu*,Optimization of mobile phase for the determination of Esomeprazole and related compounds and investigation of stress degradation by LC-MS. Journal of Separation Science[J]. 2013, 36(7): 1200-8.
Patents
1. ZL 200710170415.3
2. Zl 200410066519.6
3. Zl 200410093133.4
4. ZL201110442493.0