Dr. Yan Li obtained her Ph. D. from Department of Chemistry, Fudan University in 2008. She was appointed as a staff member at School of Pharmacy, Fudan University thereafter and promoted to associate professor in 2011. She engaged in analytical chemistry teaching and pharmaceutical analysis related researches. She published more than 50 academic papers in English, and accessed to four domestic invention patents. She received the Nomination Award for the National Excellent Doctoral Dissertation of China in 2010, and the 2nd prize of Natural Science Award from Ministry of Education, China in 2012. She is now the member of Pharmaceutical analysis Specialized Committee in Shanghai Pharmaceutical Association. Her research interest mainly focuses on development of new solid-phase extraction (SPE) methods based on functionalized nancomposites for analysis of trace components in complex biosamples.
Sample preparation; Chromatography; Nanocomposites; Solid phase extraction
Education
2003.07-2008.06 Ph.D. in Analytical Chemistry, Fudan University
1999.09-2003.06 B.A. in Chemistry, Fudan University
Professional Experiences
2008.07-2011.09, Lecturer, Pharmaceutical Analysis Department, School of Pharmacy, Fudan University
2011.09-2017.12, Associate Professor, Pharmaceutical Analysis Department, School of Pharmacy, Fudan University
2017.12-present, Professor, Pharmaceutical Analysis Department, School of Pharmacy, Fudan University
Teaching Activities
Chemical Analysis & Instrumental Analysis, two compulsory courses for undergraduates of pharmacy;
Introduction to modern Pharmacutical analysis, an elective course for graduates of pharmacy.
Awards & Honors
Shanghai Talent Development Fund (2016)
Second Prize of the Ministry of Education Natural Science Award (2012)
Memberships
Committee member of the Pharmaceutical Analysis Professional Committee of Shanghai Pharmaceutical Association 11th council.
Reviewer of Journal of Chromatography A, ACS Applied Materials & Interfaces, Analytica Chimica Acta and Analytical Chemistry.
Selected Publications
1. Feng, J., She, X., He, X., Zhu, J., Li, Y.*, Deng, C., Synthesis of magnetic graphene/mesoporous silica composites with boronic acid-functionalized pore-walls for selective and efficient residue analysis of aminoglycosides in milk; Food Chemistry, 2018, 239:612–621
2. Jiang, J., Sun, X., Li, Y.*, Deng, C., Guan, G., Facile synthesis of Fe3O4@PDA core-shell microspheres functionalized with various metal ions: A systematic comparison of commonly-used metal ions for IMAC enrichment; Talanta, 2018, 178: 600–607
3. Xie, Y., Deng, C.*, Li, Y.*, Designed synthesis of ultra-hydrophilic sulfo-functionalized metal-organic frameworks with a magnetic core for highly efficient enrichment of the N-linked glycopeptide; Journal of Chromatography A, 2017, 1508:1-6.
4. Xu, C., Yu, Y., Ling, L., Sun X., Li, Y.*, Duan, G.*, Novel strategy for the facile enrichment of isopentenyl pyrophosphate in rat plasma via Ti4+-immobilized polydopamine@Fe3O4 core–shell microsphere; Journal of Separation Science, 2017, 40:2278–2285.
5. Feng, J.,He, X.,Liu, X.,Sun, X., Li, Y.*, Preparation of magnetic graphene/mesoporous silica composites with phenyl-functionalized pore-walls as the restricted access matrix solid phase extraction adsorbent for the rapid extraction of parabens from water-based skin toners, Journal of Chromatography A , 2016, 1465:20-29.
6. Feng, J.,Liu, X., Li, Y. *,Duan, G.,Microwave-assisted enzymatic hydrolysis followed by extraction with restricted access nanocomposites for rapid analysis of glucocorticoids residues in liver tissue, Talanta, 2016, 159:155-162.
7. Ling, J., Yu, Y.,Zhu, J., Li, Y., Ling, L., Wang, L., Xu, C. *, Duan, G. *, A highly sensitive HPLC-MS/MS method for quantification of 20(S)-protopanaxadiol in human plasma and its application in phase IIa clinical trial of a novel antidepressant agent, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2 016, 1031: 214-220 .
8. Sun, N., Yao, J., Wang, J.,Zhang, X., Li, Y. *, Deng, C. *, Magnetic nanoporous hybrid carbon from core-shell metal-organic frameworks for glycan extraction, RSC Advances, 2016, 6(41):34434-34438.
9. Liu, X..,Feng, J., Sun, X.,Li, Y.*, Duan, G. L. Three-layer structure graphene/mesoporous silica composites incorporated with C8-modified interior pore-walls for residue analysis of glucocorticoids in milk by liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, 2015, 884: 61-69.
10. Sun, X., Liu, X., Feng, J., Li, Y.*, Deng, C., Duan, G.Hydrophilic Nb5+-immobilized magnetic core–shell microsphere – A novel immobilized metal ion affinity chromatography material for highly selective enrichment of phosphopeptides. Analytica Chimica Acta, 2015, 880: 67-76.
11. Yan, Y., Sun, X., Deng, C.*, Li, Y.*, Zhang, X., Metal Oxide Affinity Chromatography Platform-Polydopamine Coupled Functional Two-Dimensional Titania Graphene Nanohybrid for Phosphoproteome Research [J]. Analytical Chemistry, 2014, 86 (9): 4327-4332.
12. Wang, M., Deng, C.*, Li, Y.*, Zhang, X., Magnetic Binary Metal Oxides Affinity Probe for Highly Selective Enrichment of Phosphopeptides [J]. Acs Applied Materials & Interfaces, 2014, 6 (14): 11775-11782.
13. Sun, N., Deng, C.*, Li, Y.*, Zhang, X., Highly Selective Enrichment of N-Linked Glycan by Carbon-Functionalized Ordered Graphene/Mesoporous Silica Composites [J]. Analytical Chemistry, 2014, 86 (4): 2246-2250.
14. Liu, X., Yu, Y., Zhao, M., Zhang, H., Li, Y.*, Duan, G., Solid phase extraction using magnetic core mesoporous shell microspheres with C18-modified interior pore-walls for residue analysis of cephalosporins in milk by LC-MS/MS [J]. Food Chemistry, 2014, 150: 206-212.
15. Liu, X., Yu, Y., Li, Y.*, Zhang, H., Ling, J., Sun, X., Feng, J., Duan, G., Fluorocarbon-bonded magnetic mesoporous microspheres for the analysis of perfluorinated compounds in human serum by high-performance liquid chromatography coupled to tandem mass spectrometry [J].Analytica Chimica Acta, 2014, 844: 35-43.