1. Bioactive substances of plant endophytes;
2. Biotransformation of steroids and natural products;
3. Microbial fermentation;
4. Evaluation of anti-infective agents
Education
2003.09-2008.07 Ph.D., School of Pharmacy, Fudan University
1993.09-1997.07 Master, School of Pharmacy, Fudan University
1986.09-1991.07 Bachelor, School of Pharmacy, Shanghai Medical University
Professional Experiences
2008.11- Associate Professor, Department of Microbiological ＆ Biochemical Pharmacy, School of Pharmacy, Fudan University
1997.7-2008.10 Lecturer, Department of Biosynthesis, School of Pharmacy, Fudan University
1991.07-1997.06 Assistant, Department of Biosynthesis, School of Pharmacy, Shanghai Medical University
Teaching Activities
Courses taught: Pharmaceutical Microbiology, Biopharmaceutics, Biopharmaceutical technology, Biosynthetic medicinal chemistry
Award, Honors and Memberships
2005 The third award of technology improvement, Shanghai China
Member, New drug evaluation expert of Department of Agriculture
Grants & Projects
1. National Mega R&D Program on “Major Drug Discovery and Developmen” (2008ZX09301-011), as project leader
2. National Mega R&D Program on “Major Drug Discovery and Developmen” (2015-2016), as project leader
3. Justice department cooperation program (2015-2016), as project leader
4. Study on the fermentation of Spinosad. Enterprise technology development project. 2015-2017, as project leader.
5. Study on combination of anti-infective agents, Enterprise technology development project(2017-2018), as project leader
6. Evaluation of the anti - infective activity of Dalbavacin, Enterprise technology development project(2017-2018), as project leader
7. Evaluation of the anti - infective activity of Tedizolid Phosphate, Enterprise technology development project(2017-2018), as project leader
Selected Publications（latest 5 yrs，<20 papers）
1. Jiyang Li, Weina Wang, Lei Han, Meiqing Feng, Hui Lu, Li Yang, Xiangxiang Hu, Si Shi, Shanshan Jiang, Qian Wang, Li Ye*. Human apolipoprotein A-I exerts a prophylactic effect on high fat diet-induced atherosclerosis in a rabbit model via inflammation inhibition. Acta Biochimica et Biophysica Sinica. 2017, 49(2), 149-158.
2. Xiang Wang, Jun Li, Shui Yu, Li Ye, Meiqing Feng and Jiyang Li. Peniproline A, a new 1-phenylamino-2-pyrrolidone metabolite from the endophytic fungus Penicillium decumbens CP-4. Natural Product Research, 2017,15(31)1772-1777.
3. Duopeng An, Jun Li, Zhongbin Guan,, Xiang Wang, Shui Yu,, Yunxin Zhu, Hai Huang, Xiaoyuan Yang, Jiyang Li.In vitro Broad Antiviral Function against HBV, HSV, H3N2 Replication by Baicalin and Oroxylin A-7-O-Β-D-Glucoside.Virology & Mycology.2017,6(1):165-170
4. Zhongbin Guan, Xiang Wang, Shanshan Jiang, Jun Li, Shui Yu, Jiyang Li*. Baicalein 6-methyl ether 7-glucoside induced apoptosis in Hela cells via Caspase dependent pathway. Int. J. Clin. Exp. Med. 2017;10(4):6696-6703
5. Duopeng An,Xiang Wang,Jun Li, Shanshan Jiang, Jiyang LI*.The activity of Fungichromin against the Formationg of Candida albicans Biofilm. Biol.Pharm.Bull,2016,39:1948-1954.
6. Jiyang Li, Hang Shi, Hui Zhang, Jie Zhang, Hongying Sun. Effect of 5-aminolevulinic acid photodynamic therapy on Candida albicans Biofilma: in vitro study. Photodiagnosis and Photoaynamic Therapy.2016,15:40-45
7. Duopeng An,Xiang Wang,Jun Li, Yu Shui, Jiyang LI*. Chinese Journal of Modern Applied Pharmacy,2017,8:1078-1083
