研究方向

主要从事现代仪器分析技术在药物筛选、药效评价的应用研究。包括：药物质量控制，质量标准建立，未知化合物结构鉴定、体内外药物分析、药动药代分析、基于质谱技术的代谢组、脂质组分析等等。参与国家自然基金面上项目4项，上海市基础研究重点项目1项，上海市创新行动计划1项。2009年主要参与基金项目：沪浦发改投2007133号，建设复旦和张江集团联合张江测试平台，并在2010-2012年负责该平台的管理工作。授权专利两项,申请专利三项。

2012年度因表现突出, 荣获上海市大型仪器设施共享服务(技术类)先进个人。

代表性论著

1.     Cao, Z. L., Zhou, W., Zhang, C. * and Yang, P*. (2023). Affinity Analysis of Recombinant Humanized Anti-VEGF Biosimilars with Fc Receptors. Bio-101 e1011004. Doi: 10.21769/BioProtoc.1011004

2.     Zhonglian Cao, Hui Zhao, Jiajun Fan, Yilan Shen, Lei Han, Guangjun Jing, Xian Zeng, Xin Jin, Zeguo Zhu, Qi Bian,Yanyang Nan, Xiaozhi Hu, Xiaobin Mei*, Dianwen Ju*, Ping Yang*. Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response. Cell Death Discovery, 2023, 9:8

3.     Qiao Zhang; Xiaomin Guo; Cao Xie; Zhonglian Cao; Xin Wang; Li Liu*; Ping Yang* ; Unravelingthe metabolic pathway of choline-TMA-TMAO: Effects of gypenosides and implications for the therapy of TMAO related diseases, Pharmacological Research, 2021, 173(173)

4.     王昕，郭晓敏，程捷恺，刘莉，杨萍*, 基于UHPLC-Q-TOF-MS/MS和LTQ-MSn联用技术快速鉴定绞股蓝皂苷类化学成分, 中国药学杂志，2020，24，2044-2051

5.     Xin Wang, Dan Li, Xiaomin Guo, Qiao Zhang, Xueling Liao, Zhonglian Cao, Li Liu*, Ping Yang*. ComMSnDB—An automatable strategy to identify compounds from MS data sets (identi-fication of gypenosides as an example). Journal of agriculture food and chemistry. 2020, 68(41):11368-11388

6.     Peng Xu, Chen Xu, Xiaoxia Li, Dan Li, Yan Li, Jiebing Jiang, Ping Yang *, Gengli Duan *. Rapid Identification of Berberine Metabolites in Rat Plasma by UHPLC-Q-TOF-MS. Molecules. 2019,24,1994.

7.     Zhihong Li, Xiaomin Guo, Zhonglian Cao, Xiujie Liu, Xueling Liao, Chao Huang,Wenqi Xu, Li Liu*, Ping Yang*. New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS. Talanta. 2018,189:606-621

8.     郭晓敏，程捷恺，张明，李丹，曹忠莲，杨萍*, UHPLC/MSn质谱树技术与Q/TOF联用在利舒康胶囊成分鉴定中的应用，中草药，2017，10，1944-1956

9.     Zhonglian Cao, Dan Li, Li Liu, Ping Yang*. Effect of Novel 5-Substituted Tetrandrine Derivatives on P-Glycoprotein-Mediated Inhibition and Transport in Caco-2 Cell, Oncology Letters. 2018,16: 6808-6814

10.   Dan Li, zhonglian Cao, Xueling Liao, Ping Yang*, Li Liu*. The development of a quantitative and qualitative method based on UHPLC-QTOFMS/MS for evaluation paclitaxel–tetrandrine interaction and its application to a pharmacokinetic study, Talanta. 2016,160:256-267

11.   Zhonglian Cao, Xiaoxia Li, Xueling Liao, Ping Yang*. Development of an HPLC-FLD Method for Determination of Rhodamine-123 in Caco-2 Cell-Based Permeability Studies, Chromatographia. 2016,79:261-266

12.   Zhonglian Cao, Meredith Wright, Jiekai Cheng, Xiaoxing Huang, Li Liu, Lixing Wu, Ping Yang*, The novel bis-benzylisoquinoline PY35 reverses P-glycoprotein-mediated multidrug resistance, Oncology Reports 2014, 32(3): 1211-1217

13.   李蓓妤，朱依谆，杨萍*， LC-MS法测定大蒜提取物中S-烯丙基-L-半胱氨酸的含量，复旦学报医学版 2010年 37卷1期