1993.09 – 1997.06 上海医科大学药学院药学专业本科生，获理学学士学位
1999.09 – 2005.12 复旦大学药学院药剂学专业博士研究生，获理学博士学位
1997.07 – 2001.12 复旦大学药学院药物分析教研室，助教
2002.01 – 2008.11 复旦大学药学院药剂学教研室，讲师
2008.12 – 2014.11 复旦大学药学院药剂学教研室，副教授，硕导
2014.12 – 至今 复旦大学药学院药剂学教研室，教授，博导
教授，教育部新世纪优秀人才支持计划入选者，上海市优秀学术带头人
博士生导师
1. 国家自然科学基金面上项目，主持，2026.01-2029.12
2. 国家自然科学基金面上项目，主持，2024.01-2027.12
3. 国家自然科学基金重大研究计划培育项目，2021.01-2023.12
4. 国家自然科学基金面上项目，主持，2019.01-2022.12
1. 上海市优秀学术带头人,颁发单位：上海市科学技术委员会，2021年
2. 教育部新世纪优秀人才，颁发单位：教育部，2012年
3. 中国药学会石药青年药剂学奖，颁发单位：中国药学会，2012年
4. 脑部肿瘤靶向递药研究，教育部科技进步奖二等奖（主要完成人4/7），2017年
5. 脑部肿瘤靶向递药研究，上海市自然科学奖二等奖（主要完成人4/5），2016年
6. 阿尔茨海默病靶标新药的基础和临床研究以及早期干预策略，上海市自然科学奖一等奖（主要完成人9/16），2017年
7. 多肽介导的脑胶质瘤靶向递药策略研究，上海市研究生优秀成果（学位论文）指导教师，2016年
8. 多肽介导的纳米递释系统靶向治疗脑胶质瘤研究，上海市研究生优秀成果（学位论文）指导教师，2015年
9. 细胞穿膜肽修饰的纳米递释系统用于脑靶向和肿瘤靶向研究，上海市研究生优秀成果（学位论文）指导教师，2014年
10. 2025年度复旦大学优秀博士学位论文指导教师
1. 靶向递药系统
2. 药物制剂体内药动学及成药性评价
3. 药物新剂型与新制剂的研究开发
肿瘤免疫治疗（难治性肿瘤如脑胶质瘤，胰腺癌的免疫治疗策略及肿瘤疫苗的设计）
1.Huang Yukun, Chen Jun*. Dual-mechanism based CTLs infiltration enhancement initiated by Nano-sapper potentiates immunotherapy against immune-excluded tumors. Nature Communications. 2020, 11(1):622.
2. Zhou Songlei, Chen Jun*, Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma, Nature Communications. 2023, 14(1):435.
3. Zhou Songlei, Chen Jun *, Immuno-Initiator Rectifies Immunodeficiency to Restore Immune Function and Potentiate Immunotherapy against IDH Mutant Glioma, ACS Nano, 2025, 19(29):26980-27004.
4. Liang Kaifan, Chen Jun*, Biologically Self-Assembled Tumor Cell Derived Cancer Nanovaccines as an All-in-One Platform for Cancer Immunotherapy, ACS Nano. 2024, 18(8):6702-6717.
5. Gong Jianing, Chen Jun*. Leveraging Naturally Assembled Tumor Extracellular Vesicles as Self-Adjuvanting Nanovaccines to Potentiate Cancer Immunotherapy via cGAS/STING Activation. ACS Nano 2026, 20 (8), 6742–6756.
6. Zhou Songlei, Chen Jun*, Engineering ApoE3-incorporated biomimetic nanoparticle for efficient vaccine delivery to dendritic cells via macropinocytosis to enhance cancer immunotherapy. Biomaterials. 2020, 235:119795.
7. Kang Ting, Chen Jun*,Necroptotic Cancer Cells-Mimicry Nanovaccine Boosts Anti-tumor Immunity with Tailored Immune-stimulatory Modality. Biomaterials. 2018, 164:80-97.
8. Zhou Songlei, Chen Jun*. Targeting Immunosuppressive Network in Glioblastoma: Emerging Strategies to Overcome Immunodeficiency and Enhance Therapeutic Efficacy. Acta Pharm. Sin. B 2026, 16 (3), 1272–1291.
肿瘤靶向治疗策略（肿瘤转移，难治性肿瘤如胰腺癌等肿瘤微环境调节策略）
1. Xu Minjun, Chen Jun*,Systemic metastasis-targeted nanotherapeutic reinforces tumor surgical resection and chemotherapy. Nature Communications. 2021, 12(1):3187.
2. Huang Yukun, Chen Jun*, Synthetically Lethal Biomimetic Nutri-hijacker Hitchhikes and Reprograms KRAS MutationDriven Metabolic Addictions for Pancreatic Ductal Adenocarcinoma Treatment, ACS Nano. 2023, 17: 14014−14031.
3. Huang Yukun, Chen Jun*, High-density lipoprotein-based nanoplatform reprograms tumor microenvironment and enhances chemotherapy against pancreatic ductal adenocarcinoma, Biomaterials, 2025, 318:123147.
4. Jiang Tianze, Chen Jun*, Biguanide-anchored albumin-based nanoplatform inhibits epithelial-mesenchymal transition and reduces the stemness phenotype for metastatic cancer therapy, Acta Biomaterialia. 2023 :S1742-7061(23)00551-2.
5. Jiang Tianze, Chen Jun*, Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment. J Nanobiotechnology. 2022, 20(1):394.
6. Chen Yu, Chen Jun*. Tailored Chemodynamic Nanomedicine Improves Pancreatic Cancer Treatment via Controllable Damaging Neoplastic Cells and Reprogramming Tumor Microenvironment. Nano Letters. 2020，20(9):6780-6790.
7. Kang Ting, Chen Jun *，Nanoparticles Coated with Neutrophil Membranes Can Effectively Treat Cancer Metastasis[J]. ACS Nano. 2017, 11, 1397-1411
8. Jiang Gan, Chen Jun*. Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis. Advanced. Science. 2020, 7, 1903290(1-14).
9. Jiang Tianze, Chen Jun*. Metformin and Docosahexaenoic Acid Hybrid Micelles for Premetastatic Niche Modulation and Tumor Metastasis Suppression. Nano Lett. 2019, 19:3548−3562.
10. Pei Yuanyuan, Chen Jun*. Sequential Targeting TGF-β Signaling and KRAS Mutation Increases Therapeutic Effcacy in Pancreatic Cancer.. Small. 2019，15: 1900631 (1-15)
脑部疾病（颅脑损伤，脑卒中，脊髓损伤等）靶向治疗策略（采用干细胞及细胞外囊泡等策略）
1. Tong Shiqiang, Chen Jun*. Self-Assembling Scaffolds Epigenetically Reactivate and Electroactively Guide Neuronal Regeneration to Restore Central Neural Circuits. Nat. Commun. 2026, 17 (1), 5987.
2. Li Chang, Chen Jun*. Nanozyme-Switched Efferocytosis Initiation Platform Orchestrates Pathological Network Reprogramming to Promote Functional Recovery after Spinal Cord Injury. ACS Nano 2026, 20 (20), 14891–14909.
3.You Yang, Chen Jun*, Tailored Apoptotic Vesicle Delivery Platform for Inflammatory Regulation and Tissue Repair to Ameliorate Ischemic Stroke, ACS Nano. 2023, 17:8646-8662.
4. Tong Shiqiang, Chen Jun *, Nano-Plumber Reshapes Glymphatic-Lymphatic System to Sustain Microenvironment Homeostasis and Improve Long-Term Prognosis after Traumatic Brain Injury. Advanced Science. 2023, 2304284(1-21).
5. Xu Jianpei, Chen Jun*, Bioorthogonal microglia-inspired mesenchymal stem cell bioengineering system creates livable niches for enhancing ischemic stroke recovery via the hormesis, Acta Pharmaceutica Sinica B. 2024;14(3):1412-1427.
6. You Yang, Chen Jun*, Surface-tethered ROS-responsive micelle backpacks for boosting mesenchymal stem cell vitality and modulating inflammation in ischemic stroke treatment, Journal of Controlled Release. 2023, 362:210–224.
7. Xu Jianpei, Chen Jun*, Vitality-Enhanced Dual-Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy. Small, 2022,18(47):e2203431.
8. Huang Meng, Chen Jun*, Comparative Proteomics Inspired Self-Stimulated Release Hydrogel Reinforces the Therapeutic Effects of MSC-EVs on Alzheimer's Disease. Advanced Materials. 2023:e2311420.
炎症相关疾病（痛风，心肌缺血再灌注等）靶向治疗策略
1. Ma Chuchu, Chen Jun*, Metabolic Reprogramming of Macrophages by Biomimetic Melatonin-Loaded Liposomes Effectively Attenuates Acute Gouty Arthritis in a Mouse Model, Advanced Science. 2025, e2410107.
2. Ma Chuchu, Chen Jun*, Prussian blue-based nanoplatform integrating urate oxidase with mild photothermal effects for gout treatment, Nano Today, 2025, 61: 102593
3.Ma Fenfen, Chen Jun*. Engineered Mesenchymal Stem Cells for Targeted Delivery of H2S to Suppress cGAS-STING Inflammation and Enhance Cardioprotection in Myocardial Ischemia-Reperfusion. J. Controlled Release 2026, 389, 114484.
