1971年8月出生，1999年毕业于华西医科大学药学院药剂学专业，获博士学位。同年7月进入上海市中药研究所工作，2001年12月任高级工程师
2001年7月至2005年4月曾任上海市中药研究所常务副所长，2005年5月作为复旦大学引进人才进校工作
2009年7月至2010年8月于美国密西根大学药学院做访问学者
2007年6月至2013年1月担任复旦大学药学院药剂学教研室主任
2012年12月至2021年8月任复旦大学药学院副院长
2021年9月至今任复旦大学药学院党委书记
2023年3月至今任“克服递药屏障高端制剂”全国重点实验室副主任
2024年1月至今任衢州复旦研究院院长
1. 基于疾病病理特征的靶向给药系统研究
2. 口服给药系统设计及吸收机制研究
3. 中药新型给药系统研究
4. 药物新制剂新剂型研究开发
主持国家重大新药创制专项、国家自然科学基金等国家及省部级研究课题30余项，在Science Advances、Nature Communications、Cell Biomaterials、Journal of Controlled Release等国内外杂志发表学术论文240余篇，其中SCI论文140余篇；主编《药剂学》、《生物药剂学与药物动力学》等规划教材或专著6部，副主编教材或专著6部，上海市精品课程《药物动力学》负责人。完成了30余项企业合作项目的研究开发，获新药证书或临床批件17项，获授权发明专利30余项。
国家药品注册审评专家咨询委员会委员
国家中药品种保护审评专家
中国药学会药剂专业委员会副主任委员
世界中医药学会联合会中药新型给药系统专业委员会副会长兼秘书长
世界中医药学会联合会经皮给药专业委员会副会长
中国民族医药学会经皮治疗分会副会长
中国药学会工业药剂学专业委员会委员
中华民族团结进步协会中华传统医药委员会委员
上海市药学会副理事长
上海市药学会药剂专委会主任委员
上海市中医药学会中药分会副主任委员
《Pharmaceutical Fronts》副主编，《Pharmaceutical Science Advances》副主编
《国际药学研究》、《中国医药工业杂志》、《中成药》等杂志编委
2002年荣获中国药学会第六届全国青年药学科技工作者最新科研成果学术交流会优秀论文一等奖。
2002年荣获上海市 “讲理想、比贡献”十佳先进个人
2003年被共青团上海市委员会授予“上海市新长征突击手”称号
2004年被上海市人民政府授予2001-2003年度“上海市劳动模范”荣誉称号
2004年6月被上海市国有资产管理委员会授予“优秀共产党员”荣誉称号
2011年10月 获中国药学会-石药集团青年药剂学奖
2014年5月 获上海市优秀技术带头人荣誉称号
2017年12月荣获上海产学研合作优秀项目奖二等奖（排名第一）
2018年10月荣获首届人卫慕课在线开放课程建设比赛本科组一等奖
2018年11月 荣获四川省科技进步三等奖（排名第三）
2018年12月 荣获“上海市教育系统优秀劳模工作室”称号
2021年6月 荣获“复旦大学优秀共产党员”称号
2021年9月 荣获“上海市劳模创新工作室”称号
2023年3月 荣获“一健康基金”优秀教师奖二等奖
2024年6月 荣获复旦大学第十一届“研究生心目中的好导师”称号
1.《药剂学》主编，中国医药科技出版社，2025年8月出版
2.《生物药剂学与药物动力学》主编，中国医药科技出版社，2021年7月出版
3.《药剂学》副主编，高等教育出版社，2021年4月出版
4.《现代中药制剂设计》主编，中国医药科技出版社，2020年6月出版
5.《生物药剂学与药物动力学》主编，中国医药科技出版社，2016年1月出版
6.《药剂学》主编，人民卫生出版社，2015年4月出版
7.《药剂学》副主编，高等教育出版社，2014年3月出版
8.《现代药物动力学》副主编，人民卫生出版社，2011年12月出版
9.《现代中药制剂设计理论与实践》副主编，人民卫生出版社，2010年5月出版
10.《图解药剂学》副主编，人民卫生出版社，2008年12月出版
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2. Jiaxuan Xia, Zicheng Gan, Shuangjia Zheng, Meichen Dong, Shengyao Liu, Zhiqing Pang, Tun Lun, Ning Gu, Defang Ouyang, Chengtao Li*, ShuangJia Zheng*, Jianxin Wang*. Geometric-aware deep learning enables discovery of bifunctional ligand-based liposomes for tumor targeting therapy. Nano Today, 2025, 61. DOI: 10.1016/j.nantod.2025.102668
3. Boshu Ouyang, Caihua Shan, Shun Shen, Xinnan Dai, Qingwang Chen, Xiaomin Su, Yongbin Cao, Xifeng Qin, Ying He, SiyuWang, Ruizhe Xu, Ruining Hu, Leming Shi, Tun Lu, Wuli Yang, Shaojun Peng , Jun Zhang*, Jianxin Wang* , Dongsheng Li*, Zhiqing Pang*. AI-powered omics-based drug pair discovery for pyroptosis therapy targeting triple-negative breast cancer. Nature Communications, 2024, 15(1). DOI: 10.1038/s41467-024-51980-9
4. Jie Liu, Ranran Li, Qinghui Fu, Yani Yang, Xiaoling Liu, Fan Xu, Hongping Qu, Jianxin Wang*, Weigen Lu*, Jun He*. Designed microchannel-based lipid nanoparticles encapsulated siRNA targeting gasdermin D for sepsis management via pulmonary delivery. Nano Today, 2025, 61. DOI: 10.1016/j.nantod.2025.102653
5. Miaomiao Zhang, Yang Li, Tongyang Xu, Botao Liu, Yue Liu, Xu Cheng, Junjie Pan*, Jianxin Wang*. A rapamycin-loading platelet membrane hybrid liposome with anti-inflammation effect and long-lasting repair capability for acute kidney injury. Journal of Controlled Release, 2025, 380: 927-942.
6. Jiaxuan Xia, Xing Chen, Meichen Dong, Shengyao Liu, Longlong Zhang, Junjie Pan*, Jianxin Wang*. Antigen self-presenting dendrosomes swallowing nanovaccines boost antigens and STING agonists codelivery for cancer immunotherapy. Biomaterials, 2025, 316:122998
7. Jiaxuan Xia, Chen Chen, Meichen Dong, Ying Zhu, Anni Wang, Shiyi Li, Ru Zhang, Chunbo Feng, Xinnan Jiang, Xinchun Xu* and Jianxin Wang*. Ginsenoside Rg3 Endows Liposomes with Prolonged Blood Circulation and Reduced Accelerated Blood Clearance. Journal of Controlled Release, 2023, 364, pp. 23-36.
8. Shiyi Li, Ru Zhang, Anni Wang, Yang Li, Miaomiao Zhang, Jisu Kim, Ying Zhu, Qizheng Wang, Yue Zhang, Ying Wei* and Jianxin Wang*. Panax Notoginseng: Derived Exosome-Like Nanoparticles Attenuate Ischemia Reperfusion Injury Via Altering Microglia Polarization. Journal of Nanobiotechnology, 2023, 21(1), p. 416.
9. Jisu Kim, Ying Zhu, Sunhui Chen, Dongdong Wang, Shuya Zhang, Jiaxuan Xia, Shiyi Li, Qiujun Qiu, Hyukjin Lee and Jianxin Wang*. Anti-Glioma Effect of Ginseng-Derived Exosomes-Like Nanoparticles by Active Blood–Brain-Barrier Penetration and Tumor Microenvironment Modulation. Journal of Nanobiotechnology, 2023, 21(1), p. 253.
10. Qiujun Qiu, Sunhui Chen, Huining He, Jixiang Chen, Xinyi Ding, Dongdong Wang, Jiangang Yang, Pengcheng Guo, Yang Li, Jisu Kim, Jianyong Sheng, Chao Gao, Bo Yin, Shihao Zheng and Jianxin Wang*. An Injectable Signal-Amplifying Device Elicits a Specific Immune Response Against Malignant Glioblastoma. Acta Pharmaceutica Sinica B, 2023, 13(12), pp. 5091-5106.
11. Qiujun Qiu, Xinyi Ding, Jixiang Chen, Sunhui Chen and Jianxin Wang*. Nanobiotechnology-Based Treatment Strategies for Malignant Relapsed Glioma. Journal of Controlled Release, 2023, 358, pp. 681-705.
12. Yang Li, Miaomiao Zhang, Shiyi Li, Longlong Zhang, Jisu Kim, Qiujun Qiu, Weigen Lu* and Jianxin Wang*. Selective Ischemic-Hemisphere Targeting Ginkgolide B Liposomes with Improved Solubility and Therapeutic Efficacy for Cerebral Ischemia-Reperfusion Injury, Asian Journal of Pharmaceutical Sciences, 2023, 18(2), p. 100783.
13. Ying Zhu, Anni Wang, Shuya Zhang, Jisu Kim, Jiaxuan Xia, Fengxue Zhang, Dan Wang, Qi Wang* and Jianxin Wang*. Paclitaxel-Loaded Ginsenoside Rg3 Liposomes for Drug-Resistant Cancer Therapy by Dual Targeting of the Tumor Microenvironment and Cancer Cells. Journal of Advanced Research, 2023, 49, pp. 159-173.
14. Sunhui Chen, Qiujun Qiu, Dongdong Wang, Dejun She, Bo Yin, Guolong Gu, Meihong Chai, Dong Nyoung Heo, Huining He* and Jianxin Wang*. Dual-Sensitive Drug-Loaded Hydrogel System for Local Inhibition of Post-Surgical Glioma Recurrence. Journal of Controlled Release, 2022, 349, pp. 565-579.
15. Jiaxuan Xia, Shaojie Ma, Xi Zhu, Chen Chen, Ru Zhang, Zhonglian Cao, Xing Chen, Longlong Zhang, Ying Zhu, Shuya Zhang, Shiyi Li, Guolong Gu, Xunbin Wei, Kunqian Yu and Jianxin Wang*. Versatile Ginsenoside Rg3 Liposomes Inhibit Tumor Metastasis by Capturing Circulating Tumor Cells and Destroying Metastatic Niches. Science Advances, 8(6), p. eabj1262.
16. Longlong Zhang, Yuefei Zhu, Xunbin Wei, Xing Chen, Yang Li, Ying Zhu, Jiaxuan Xia, Yiheng Huang, Yongzhuo Huang, Jianxin Wang* and Zhiqing Pang*. Nanoplateletsomes Restrain Metastatic Tumor Formation through Decoy and Active Targeting in a Preclinical Mouse Model, Acta Pharmaceutica Sinica B, 2022, 12(8), pp. 3427-3447.
17. Xing Chen, Xiang Ling, Jiaxuan Xia, Ying Zhu, Longlong Zhang, Yuwei He, Anni Wang, Guolong Gu, Bo Yin* and Jianxin Wang*. Mature Dendritic Cell-Derived Dendrosomes Swallow Oxaliplatin-Loaded Nanoparticles to Boost Immunogenic Chemotherapy and Tumor Antigen-Specific Immunotherapy. Bioactive Materials, 2022, 15, pp. 15-28.
18. Ying Zhu, Jianming Liang, Caifang Gao, Anni Wang, Jiaxuan Xia, Chao Hong, Zhirong Zhong, Zhong Zuo, Jisu Kim, Hongwei Ren, Shiyi Li, Qi Wang, Fengxue Zhang* and Jianxin Wang*. Multifunctional Ginsenoside Rg3-Based Liposomes for Glioma Targeting Therapy. Journal of Controlled Release, 2021, 330, pp. 641-657.
19. Chao Hong, Jianming Liang, Jiaxuan Xia, Ying Zhu, Yizhen Guo, Anni Wang, Chunyi Lu, Hongwei Ren, Chen Chen, Shiyi Li, Dan Wang, Huaxing Zhan and Jianxin Wang*. One Stone Four Birds: A Novel Liposomal Delivery System Multi-Functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy. Nano-Micro Letters, 2020, 12(1), p. 129.
20. Jianming Liang, Ying Zhu, Caifang Gao, Chengli Ling, Jing Qin, Qi Wang, Yongzhuo Huang, Weigen Lu* and Jianxin Wang*. Menthol-Modified Bsa Nanoparticles for Glioma Targeting Therapy Using an Energy Restriction Strategy. NPG Asia Materials, 2019, 11(1), p. 38.
21. Jia Hou, Xu Yang, Shiyi Li, Zhekang Cheng, Yuhua Wang, Jing Zhao, Chun Zhang, Yongji Li, Man Luo, Hongwei Ren, Jianming Liang, Jue Wang, Jianxin Wang* and Jing Qin*. Accessing Neuroinflammation Sites: Monocyte/ Neutrophil- Mediated Drug Delivery for Cerebral Ischemia. Science Advances, 5(7), p. eaau8301.
22. Caifang Gao, Jianming Liang, Ying Zhu, Chengli Ling, Zhekang Cheng, Ruixiang Li, Jing Qin, Weigen Lu* and Jianxin Wang*. Menthol-Modified Casein Nanoparticles Loading 10-Hydroxycamptothecin for Glioma Targeting Therapy. Acta Pharmaceutica Sinica B, 2019, 9(4), pp. 843-857.
23. Yuwei He, Ruixiang Li, Haichun Li, Shuya Zhang, Wentao Dai, Qian Wu, Lixian Jiang, Zicong Zheng, Shun Shen, Xing Chen, Yuefei Zhu, Jianxin Wang* and Zhiqing Pang*. Erythroliposomes: Integrated Hybrid Nanovesicles Composed of Erythrocyte Membranes and Artificial Lipid Membranes for Pore-Forming Toxin Clearance. ACS Nano, 2019, 13(4), pp. 4148-4159.
24. Ruixiang Li, Yuwei He, Ying Zhu, Lixian Jiang, Shuya Zhang, Jing Qin, Qian Wu, Wentao Dai, Shun Shen, Zhiqing Pang* and Jianxin Wang*. Route to Rheumatoid Arthritis by Macrophage-Derived Microvesicle-Coated Nanoparticles. Nano Letters, 2019, 19(1), pp. 124-134.
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26. Yuwei He, Ruixiang Li, Jianming Liang, Ying Zhu, Shuya Zhang, Zicong Zheng, Jing Qin, Zhiqing Pang* and Jianxin Wang*. Drug Targeting through Platelet Membrane-Coated Nanoparticles for the Treatment of Rheumatoid Arthritis. Nano Research, 2018, 11(11), pp. 6086-6101.
27. Ruixiang Li, Zhiqing Pang, Huining He, Seungjin Lee, Jing Qin, Jian Wu, Liang Pang, Jianxin Wang*and Victor C. Yang*. Drug depot-anchoring hydrogel: A self-assembling scaffold for localized drug release and enhanced stem cell differentiation. Journal of Controlled Release, 2017, 261:234-245
28. Jianyong Sheng, Huining He, Limei Han, Jing Qi, Sunhui Chen, Ge Ru, Ruixiang Li, Pei Yang, Jianxin Wang*and Victor C. Yang*. Enhancing Insulin Oral Absorption by Using Mucoadhesive Nanoparticles Loaded with LMWP-linked Insulin Conjugates. Journal of Controlled Release，2016,233:181-190
29. Huining He, Jianyong Sheng, Allan E David, Youngmin Kwon, Jian Zhang, Yongzhuo Huang, Jianxin Wang*, Victor C Yang*. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption. Biomaterials, 2013, 34(31):7733-7743
30. Ming Shen, Yongzhuo Huang, Limei Han, Jing Qin, Xiaoling Fang, Jianxin Wang*, Victor C Yang*. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment. Journal of Controlled Release, 2012, 161:884-892
