1994.09 – 1998.07 西北师范大学化学系
1998.09 – 2001.07 西北师范大学化学化工学院 有机化学专业 硕士研究生
2001.09 – 2004.09 厦门大学化学化工学院 有机化学专业 博士研究生
2004.10 – 2006.08 中国科学院上海有机化学研究所，博士后
2006.08 – 2016.12 复旦大学化学系/药学院，副研究员
2016.12 –至今 复旦大学药学院，研究员
1.活性导向天然产物及其骨架高效合成方法学研究
2.资源导向复杂海洋天然产物及氮杂环生物碱的多样性合成研究
3.复杂药物分子的高效产业化研究
1. 国家自然科学基金委面上项目:
①具有手性4-及5-芳基环戊烷骨架前列腺素类活性物质研究 (22271056)
②构象锁定小分子直链肽Dolastatin 10, Grassystatin A,Tubulysins和Symplocin A 多样性研究 (21772027)
③基于抗体药物偶联物弹头的具有抗肿瘤活性海洋天然产物Hoiamides A、Lyngbyabellin N等的多样性研究（21472022）
④具有重要生理活性海洋环肽酯Lagunamide、Apratoxins及其氟代类似物的合成和活性评价研究 (21272041)
⑤ 具有抗癌活性海洋天然产物 Leiodelide A、B 及其类似物全合成和生理活性评价研究 (21272041)
2. 国家自然科学基金委青年科学基金项目: 新型抗凝血酶抑制剂的合成 (20702007)
3. 国家自然科学基金重点项目:重要生理活性天然产物的结构多样性合成研究 (20832005, 复旦子课题负责人,总课题由厦门大学黄培强教授主持）
2012.05 第二十四届上海市优秀发明选拔赛优秀发明 金奖 (第二完成人）
2011.12 上海市药学会科技奖 二等奖（第二完成人）
2011.07 中国药学会科技奖 二等奖（第七完成人）
2010.12 上海市药学会科技奖 二等奖（第七完成人）
2005.04 甘肃省科技进步奖 二等奖 (第七完成人）
2004.07 甘肃省高校科技进步奖 一等奖 (第七完成人）
2002.10 甘肃省高校科技进步奖 二等奖 (第五完成人）
1. Chang-Hong Liu, Jia-Ming Guo, Xin Li, Jian-Ting Sun, Bang-Guo Wei* and Chang-Mei Si* SmI2-mediated intermolecular addition–elimination of piperidine and pyrrolidine N-α-radicals with arylacetylene sulfones Chem. Commun.2022, 58,10841-10844.
2.Jia-Ming Guo, Zhuo-Ya Mao, Chang-Hong Liu, Shang-Ye Yang, and Bang-Guo Wei* Palladium-Catalyzed Sequential Heck Reactions of Olefin-Tethered Aryl Iodides with Alkenes J. Org. Chem.2022, 87, 11838-11845.
3. Xiao-Di Nie, Zhuo-Ya Mao, Jia-Ming Guo, Chang-Mei Si,* Bang-Guo Wei* and Guo-Qiang LinAgNTf2‑Catalyzed Regioselective C-H Alkenylation of N,N-Dialkylanilines with Ynamides J. Org. Chem.2022, 87, 2380-2392.
4. Chao-Yu Hu, Sheng-Jie Wu, Fei He, De-Qin Cai, Zhuo-Jia Xu, Wen-Jing Ma, Ya-Ting Liu, Bang-Guo Wei,* Tie-Hai Li,* and Kan Ding*Convergent Synthesis and Anti-Pancreatic Cancer Cell Growth Activity of a Highly Branched Heptadecasaccharide from Carthamus tinctoriusAngew. Chem. Int. Ed.2022,doi.org/10.1002/anie.202202554.
5. Zhuo-Ya Mao, Xiao-Di Nie, Yi-Man Feng, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Cu(OTf)2 catalyzed Ugi-type reaction of N,O-acetals with isocyanides for the synthesis of pyrrolidinyl and piperidinyl 2-carboxamides Chem. Commun. 2021, 57, 9248-9251.
6. Zhuo-Ya Mao, Jian-Liang Ye, Xiao-Di Nie, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of Functionalized Bicyclo[2.2.2]octan-2-ones Skeleton via Tandem Process of Amino Acid Involved Formal [4+2] and Decarboxylative−Mannich Sequence J. Org. Chem.2021, 86, 3276-3286.
7. Xiao-Di Nie, Xiao-Li Han, Jian-Ting Sun, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Nickel-Catalyzed Regioselective Hydroamination of Ynamides with Secondary Amines J. Org. Chem.2021, 86, 3433-3443.
8. Zhao-Dan Chen, Wen-Ke Xu, Jia-Ming Guo, Ling Chen, Bang-Guo Wei*, Chang-Mei Si* and Guo-Qiang Lin A One-Pot Approach to 2‑Substituted-2-(Dimethoxyphosphoryl)-Pyrrolidines from Substituted tert-Butyl 4‑Oxobutylcarbamates and Trimethyl Phosphite J. Org. Chem. 2021, 86, 11442-11455.
9. Xiao-Li Han, Xiao-Di Nie, Yi-Man Feng, Bang-Guo Wei*, Chang-Mei Si* and Guo-Qiang LinIntermolecular [4+2] process of N -acyliminium ions with simple olefins for construction of functional substituted-1,3-oxazinan-2-ones Chin. Chem. Lett.2021, 32, 3526-3530.
10. Chen Wang, Zhuo-Ya Mao, Yi-Wen Liu, Qiao-E Wang, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Intermolecular [4+2] Process of N,O-acetals with Terminal Alkynes for Construction of Functional cis-Pyrido and Pyrrolo[1,2-c][1,3]oxazin-1-ones Adv. Synth. Catal. 2020, 362, 822-831.
11. Xiao-Di Nie, Zhuo-Ya Mao, Wen Zhou, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin A diastereoselective approach to amino alcohols and application for divergent synthesis of dolastatin 10 Org. Chem. Front.2020, 7, 76-103.
12. Pan Han, Zhuo-Ya Mao, Ming Li, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of Amide Enol Carbamates and Carbonates through Cu(OTf)2‑Catalyzed Reactions of Ynamides with t‑Butyl Carbamates/Carbonates J. Org. Chem.2020, 85, 4740-4752.
13. Xiao-Li Han, Xiao-Di Nie, Zhao-Dan Chen, Chang-Mei Si*, Bang-Guo Wei* and Guo-Qiang Lin Synthesis of a 3,4-Dihydro-1,3-oxazin-2-ones Skeleton via an Intermolecular [4+2] Process of N‑Acyliminium Ions with Ynamides/Terminal Alkynes J. Org. Chem. 2020, 85, 13567-13578.
14. Yan-Xue Zhang, Ling-Yan Chen*, Jian-Ting Sun, Chang-Mei Si and Bang-Guo Wei* Gold-Catalyzed Addition−N‑Boc Cleavage-Cyclization of N,O‑Acetal with Ynamides for Construction of 6‑(tert-Butyldimethylsilyl)oxytetrahydropyrrolo[1,2‑c][1,3]oxazin-1-ones J. Org. Chem. 2020, 85, 12603-12613.
15. Zhuo-Ya Mao, Yi-Wen Liu, Rui-Jun Ma, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Divergent Synthesis of N-Heterocyclic 1,6-Enynes through Zinccatalyzed Decarboxylative A3 ReactionChem. Commun.2019, 55, 14170-14173.
16. Pan Han, Zhuo-Ya Mao, Chang-Mei Si, Zhu Zhou, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Synthesis of Pyrido- and Pyrrolo[1,2‑c][1,3]oxazin-1-ones via a Nucleophilic Addition-Cyclization Process of N,O‑Acetal with Ynamides J. Org. Chem. 2019, 84, 914-923.
17. Yi-Wen Liu, Zhuo-Ya Mao, Xiao-Di Nie, Chang-Mei Si, Bang-Guo Wei* and Guo-Qiang Lin Approach to Tertiary-Type β‑Hydroxyl Carboxamides Through Sc(OTf)3‑Catalyzed Addition of Ynamides and Ketones J. Org. Chem.2019, 84, 16254-16261.
18. Xue-Mei Wang, Yi-Wen Liu, Rui-Jun Ma, Chang-Mei Si* and Bang-Guo Wei* Synthesis of 1,4- and 1,5-Amino Alcohols via Nucleophilic Addition of Semicyclic N,O‑Acetal with Organozinc Reagents J. Org. Chem. 2019, 84, 11261-11267.
19. Zhuo-Ya Mao, Yi-Wen Liu, Pan Han, Han-Qing Dong, Chang-Mei Si,* Bang-Guo Wei* and Guo-Qiang Lin Regio- and Stereoselective Cascades via Aldol Condensation and 1,3-Dipolar Cycloaddition for Construction of Functional Pyrrolizidine Derivatives Org. Lett.2018,20, 1090-1093.
20. Wen Zhou, Yan-Xue Zhang, Xiao-Di Nie, Chang-Mei Si,* Xun Sun, and Bang-Guo Wei* Approach to Chiral 1‑Substituted Isoquinolone and 3‑Substituted Isoindolin-1-one by Addition−Cyclization Process J. Org. Chem.2018,83, 9879-9889.
21. Pan Han, Zhu Zhou, Chang-Mei Si,* Xian-Yi Sha, Zheng-Yi Gu, Bang-Guo Wei* and Guo-Qiang Lin Asymmetric Synthesis of Rupestonic Acid and Pechueloic Acid Org. Lett. 2017, 19, 6732-6735.
22. Zhuo-Ya Mao, Chang-Mei Si, Yi-Wen Liu, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang LinDivergent Synthesis of Revised Apratoxin E, 30-epi-Apratoxin E, and 30S/30R‑Oxoapratoxin EJ. Org. Chem. 2017,82, 10830-10845.
23. Lu-Ping Shao, Chang-Mei Si, Zhuo-Ya Mao, Wen Zhou, Tadeusz F. Molinski,* Bang-Guo Wei* and Guo-Qiang Lin Synthesis and structure revision of symplocin A Org. Chem. Front.2017, 4, 995-1004.
24. Chang-Mei Si, Zhuo-Ya Mao, Yi-Wen Liu, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Stereoselective Formation of Chiral trans-4-Hydroxy-5-Substituted 2-Pyrrolidinones: Syntheses of Streptopyrrolidine and3-epi-Epohelmin A Org. Chem. Front.2015, 2, 1485-1499.
25. Chang-Mei Si, Zhuo-Ya Mao, Han-Qing Dong, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Divergent Method to trans-5-Hydroxy-6-alkynyl/alkenyl-2-piperidinones: Syntheses of (-)-Epiquinamide and (+)-SwainsonineJ. Org. Chem.2015, 80, 5824-5833.
26. Chang-Mei Si, Wei Huang, Zhen-Ting Du, Bang-Guo Wei* and Guo-Qiang Lin Diastereoconvergent Synthesis of trans-5-Hydroxy-6-Substituted-2-Piperidinones by Addition−Cyclization−Deprotection Process Org. Lett. 2014, 16, 4328-4331.
27. Wei Huang,Jian-Liang Ye,Wei Zheng,Han-Qing Dong and Bang-Guo Wei* Radical Migration−Addition of N-tert-Butanesulfinyl Imines with Organozinc Reagents J. Org. Chem. 2013, 78, 11229-11237.
28. Wei Huang, Rong-Guo Ren, Han-Qing Dong, Bang-Guo Wei* and Guo-Qiang Lin Diverse Synthesis of Marine Cyclic Depsipeptide Lagunamide A and Its Analogues J. Org. Chem. 2013, 78, 10747-10762.
