教育经历
1998.09 – 2003.06 中国药科大学中药学院，生药学博士
1994.09 – 1998.06 中国药科大学中药学院，中药分析学学士
2018.12 -- 今 复旦大学药学院，教授
2009.01 – 2018.12 复旦大学药学院，副研究员
2005.10 – 2008.08 美国马里兰大学(University of Maryland at College Park)，博士后
2003.07 – 2005.09 中科院上海有机化学研究所，博士后
2020.08-今 上海市药学会生药学专业委员会副主任委员
2020.12-今 上海市药学会第12届理事会理事
2020.06-今 中国康复医学会中药学与康复专业委员会第一届委员会常务委员
2015.12-今 SCI收录期刊《Current Analytical Chemistry》编委
2011.01 教育部自然科学二等奖-麦冬类中药的系统研究（第三完成人）
1. 国家自然科学基金面上项目：基于薄层自显影谱效关系-生物定量法的板蓝根抗流感病毒活性成分辨识与质量控制研究（82173967, 2022.01-2025.12）;
2. 上海市科委自然科学基金面上项目: 基于微生物转化和化学修饰探讨续随子烷二萜抑制肿瘤多药耐药性的构效关系（19ZR1406100, 2019.7-2022.07）;
3. 国家自然科学基金面上项目: 维药天山堇菜和一枝蒿治疗重症流感的物质基础研究（81473421, 2015.1-2018.12）；
4. 国家自然科学基金面上项目: 基于补体抑制作用探讨紫花地丁和夏枯草的清热药效物质（81073025, 2011.1-2013.12）；
5. 上海市科委中药现代化专项基金: 紫花地丁清热药效物质基础及其对急性肺损伤的防治作用（09dZ1970100, 2009.6-2012.6）；
6. 教育部博士点基金(新教师类) : 清热药夏枯草的清热药效物质基础研究（20100071120052, 2011.1-2013.12）；
7. “国家重大新药创制” 科技重大专项课题: 中药药效物质基础及物质资源库研究关键技术（2009ZX09502-013, 2009.1-2010.12, 课题副组长）；
8. 2010国家药品标准提高研究课题：五加皮药材、五加皮饮片国家标准的制定研究（2010.9-2012.12）.
2. 小分子天然产物的微生物转化研究。
[1] Min Jae Kim, Xinyun Zhang, Zhao Yang, Xiaofan Fan, Hongjuan Pan*, Zhihong Cheng*. Ultra-performance liquid chromatography-electrospray ionization-ion trap tandem mass spectrometry for fragmentation of cyclic dipeptides: methodology and application to the chemical profiling of the fungus Hormonema dematioides. Journal of Mass Spectrometry, 2026, 61(4): e70055.
[2] Yanzhi Sun, Qihui Guo, Zhihong Cheng*. Thermal stability, and in vitro and in vivo metabolism of four main glucosinolates in Isatis indigotica roots. Food Research International, 2025, 221: 117299.
[3] YanzhiSun#,Shaoli Xia#, Man Xue, Yue Cao, Zhihong Cheng*. Neuraminidase inhibitory constituents from Artemisia rupestris L. Chemistry & Biodiversity, 2025, 22: e202500543.
[4] Zilong Zhan, Xin Liu, Zhihong Cheng*.Enhancing lathyrane structural diversity and MDR activity by combinatorial modification of lathyrane nucleus and ester side chain: A case study of Euphorbia Factor L1 and Euphorbia Factor L3. Fitoterapia, 2024, 174: 105854.
[5] Xiaofan Fan#, Yingzhe Li#, Tao Wu, Zhihong Cheng*. Screening and identification of neuraminidase inhibitors fromBaphicacanthus cusia by a combination of affinity ultrafiltration, HPLC-MS/MS, molecular docking, and fluorescent techniques. Journal of Chromatography B, 2023, 1231: 123924.
[6] Yichao Zang, Yu Miao, Tao Wu*, Zhihong Cheng*. Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds. Journal of Chromatography A, 2021, 1638: 461597.
[7] Qihui Guo, Zeyun Li, Lulu Shen, Ying Xiao*, Zhihong Cheng*. Quantitative 1H nuclear magnetic resonance (qHNMR) methods for accurate purity determination of glucosinolates isolated from Isatis indigotica roots. Phytochemical Analysis,2021, 32: 104-111.
[8] Haiyan Feng#, Jihe Tang#, Peiliang Zhang, Yu Miao, Tao Wu*, Zhihong Cheng*. Anti-adipogenic 18,19-seco-ursane stereoisomers and oleane-type saponins from Ilex cornuta leaves. Phytochemistry, 2020, 175: 112363.
[9] Yan Qin, Boyan Gao, Haiming Shi, Jie Cao, Chengle Yin, Weiying Lu, Liangli Yu, Zhihong Cheng*. Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides in Viola tianschanica. Journal of Pharmaceutical & Biomedical Analysis, 2017,142: 113-124.
[10] Lei Zhang#, Jiyao Shi#, Jihe Tang, Zhihong Cheng*, Xiaohui Lu, Yao Kong, Tao Wu*. Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves.Analytica Chimica Acta, 2017, 967: 52-58.
[11] Yiqing Wu, Chengle Yin, Yue Cao, Xin Liu, Jinxiang Yu, Jian Zhang, Boyang Yu, Zhihong Cheng*. Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis. Journal of Molecular Catalysis B: Enzymatic, 2016, 133: S352-S359.
[12] Dongsheng Du, Yan Lu, Zhihong Cheng*, Daofeng Chen*. Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities. Journal of Ethnopharmacology, 2016, 193: 345-353.
[13] Yan Qin, Yingming Pang, Zhihong Cheng*. Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica. Phytochemical Analysis, 2016, 27(6): 364-374.
[14] Chengle Yin, Jinge Zhou, Yiqing Wu, Yue Cao, Tao Wu, Shoude Zhang, Honglin Li, Zhihong Cheng*. Pterocarpans and triterpenoids from Gueldenstaedtia verna. Fitoterapia, 2015, 106: 46-54.
[15] Jie Cao, Chengle Yin, Yan Qin, Zhihong Cheng*, Daofeng Chen. Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis. Journal of Mass Spectrometry, 2014, 49: 1010-1024.
