1998.09 – 2002.07 南京农业大学园艺学院，学士
2002.09 – 2005.01 南京农业大学，作物遗传与种质创新国家重点实验室，硕士
2005.03 – 2008.03 中国科学院昆明植物研究所，植物化学与西部植物资源持续利用国家重点实验室，博士
2008.04 – 2010.11 上海有机化学研究所，生命有机化学国家重点实验室，博士后
2010.11 – 2014.12 复旦大学药学院，讲师
2015.01 – 至今 复旦大学药学院，副教授
天然先导化合物的发现与功能研究
主要研究兴趣：
1.基于大数据的天然先导化合物的挖掘
2.基于生物合成的活性天然产物的结构创新
3.新天然产物抗感染功能研究（抗疟、抗病毒、抗菌）
1）国家自然科学基金面上项目，清热解毒傣药鹊肾树抗病毒活性成分的发现与研究（82073717）
2）国家自然科学基金面上项目，新异戊烯基酚类化合物的发现与抗糖尿病功能研究（21372049）
3）国家自然科学基金青年基金项目，以发掘基因组信息为基础的新颖硫肽类天然产物的发现研究（20902102）
4）第45批中国博士后科学基金面上资助一等资助，以挖掘基因组信息为基础的新颖抗生素的发现研究（20090450084）
5）微生物代谢国家重点实验室开放基金，四株 PPTase 高表达放线菌株的次级代谢产物研究（MMLKF24-03）
6）横向，植物病原菌RS1中的天然产物挖掘 (SGF301425)
1) Shixue Jin, Huixue Chen, Jun Zhang, Zhi Lin, Xudong Qu, Xinying Jia*, Chun Lei *. Analyzing and engineering of the biosynthetic pathway of mollemycin A for enhancing its production. Synthetic and Systems Biotechnology 2024, 9: 445-452.
2) Qin Ouyang, Yun-Xuan He, Yi-Liang Zhang, Jin-Qiu You, Mei-Hua Yu, Chun Lei*, Ai-Jun Hou*.Cardiac glycosides from Streblus asper with potential antiviral activity. Phytochemistry 2024, 219: 113990.
3) Jin-Sheng Li, Yi-Nan Liu, Jing-Ya Li, Chun Lei*, Ai-Jun Hou*. Acylphloroglucinol-monoterpene meroterpenoids from Eucalyptus tereticornis and their inhibitory activity against ATP citrate lyase. Phytochemistry 2023, 207: 113565.
4) Kai Jiang, Xiaoli Yan, Zixin Deng, Chun Lei*, Xudong Qu*. Expanding the Chemical Diversity of Fasamycin Via Genome Mining and Biocatalysis. Journal of Natural Products 2022, 85: 943-950.
5) Chun Lei, Ya-Nan Li, Jia-Nan Li, Yu-Bo Zhou, Ming-Jun Cui, Kai-Cong Fu, Jia Li, Ai-Jun Hou*. Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora. Planta Medica 2022, 88: 678-684.
6) Xiao-Tong Zhao #, Chun Lei #, Jin-Qiu You, Ting Zhao, Mei-Hua Yu, Xun-Long Shi, Xiao Hu*, Ai-Jun Hou*. Dimeric clerodane diterpenoids and antiviral constituents of Dodonaea viscosa. Bioorganic Chemistry 2021, 112: 104916.
7) Chun Lei, Xiao-Hang Wang, Yi-Nan Liu, Ting Zhao, Zhu Hu, Jing-Ya Li, Ai-Jun Hou*. Clerodane diterpenoids from Dodonaea viscosa and their inhibitory effects on ATP citrate lyase. Phytochemistry 2021, 183: 112614.
8) Xiao-Tong Zhao, Mei-Hua Yu, Shi-Yun Su, Xun-Long Shi, Chun Lei*, Ai-Jun Hou*. Cycloartane triterpenoids from Pseudolarix amabilis and their antiviral activity. Phytochemistry 2020, 171: 112229.
9) Xian-Yi Mei, Xiao-Li Yan, Hui Zhang, Ming-Jia Yu, Guang-Qing Shen, Lin-Jun Zhou, Zi-Xin Deng, Chun Lei*, Xu-Dong Qu*. Expanding the bioactive chemical space of anthrabenzoxocinones through engineering the highly promiscuous biosynthetic modification steps. ACS Chemical Biology 2018, 13: 200-206.
10) Xudong Qu, Chun Lei, and Wen Liu*. Transcriptome mining of active biosynthetic pathways and their associated products in Streptomyces flaveolus. Angew. Chem. Int. Ed. 2011, 50: 9651-9654.
