2004.9-2007.6：复旦大学药学院药物化学专业，博士
2000.9-2003.6：复旦大学药学院药物化学专业，硕士
1993.9-1997.6：华东师范大学化学系化学专业，学士
2013.12- 至今：复旦大学药学院药物化学教研室，副教授
2008.9 -2009.9：美国明尼苏达大学药学院药物化学系，博士后
1997.7- 2013.11：复旦大学药学院药物化学教研室，助教/讲师
1. 上海市“科技创新行动计划”生物医药科技支撑专项项目（21S11907200），新型双阳离子硼修饰BODIPY抗菌光敏剂的临床前研究，主持
2. 上海市“科技创新行动计划”自然科学基金项目（21ZR1425600），新型小分子Myostatin通路抑制剂的设计、合成及其抗肿瘤恶病质作用研究，主持
3. 国家自然科学基金面上项目（21572037），新结构类型Hedgehog通路抑制剂的设计、合成和构效关系研究，主持
4. 上海市自然科学基金面上项目（12ZR1403300），含氮杂四元环骨架的新型Hedgehog通路抑制剂的设计、合成及抗肿瘤活性研究，主持
5. 国家自然科学基金面上项目（81573363），基于水淬灭近红外荧光探针的口服脂质纳米给药系统体内命运与作用机制研究，参与
6. 国家自然科学基金面上项目（81872816），新型水淬灭近红外荧光探针的设计及其在纳米粒体内过程研究中的应用，参与
1. 代谢、肿瘤相关疾病治疗小分子药物先导化合物的发现与优化
2. 抗肿瘤、抗感染光动力药物及荧光示踪剂的研究
1. Mengqian Wang, Weili Zhao*, Xiaochun Dong*. Design, Synthesis, and Evaluation of Boron Dipyrromethene-Based Fluorescent Probes Targeting BRAF for Melanoma Diagnosis. ChemMedChem, 2025, e202500095
2. Bin Rong, Xiaochun Dong*, Weili Zhao*. Synthesis and evaluation of a novel BODIPY fluorescent probe targeting integrin αvβ3 for cancer diagnosis. Eur. J Med. Chem.,2025, 282: 117056
3. Xiaofan Gu, Shanshan Lu, Shuang Xu, Yiwei Li, Meng Fan, Guangyu Lin, Yiyuan Liu, Yun Zhao, Weili Zhao, Xuan Liu, Xiaochun Dong*, Xiongwen Zhang*. Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-kB signaling and oxidative stress. Genes & Diseases, 2025, 12(2): 101292
4. Chang Liu, Chuan Liu, Xin Ji, Weili Zhao*, Xiaochun Dong*. Synthesis and Photodynamic Activities of Pyridine- or Pyridinium-Substituted Aza-BODIPY Photosensitizers. J. Med. Chem., 2024, 67(17): 15908−15924
5. Chang Liu, Xin Ji, Zhiliang Yu, Shaohui Zhang, Rong Zhang, Weili Zhao, Xiaochun Dong*. Discovery of Subcellular-Targeted Aza-BODIPY Photosensitizers for Efficient Photodynamic Antitumor Therapy. J. Med. Chem., 2023, 66 (11): 7205-7220
6. Li Ruan, Junping Bai, Xin Ji, Weili Zhao, Xiaochun Dong*. A series of meso amide BODIPY based lysosome-targeting fluorescent probe with high photostability and sensitivity. Analytica Chimica Acta, 2022, 1205: 339771
7. Chang Liu, Yue Jin, Xin Ji, Weili Zhao*, Xiaochun Dong*. Access to Pyridinyl or Pyridinium Aza-BODIPYs with Tunable Near-Infrared Fluorescence through ICT from 4-Pyridinyl Pyrroles. Chem. Eur. J., 2022, e202201503
8. Shaohui Zhang, Xin Ji, Rong Zhang, Weili Zhao*, Xiaochun Dong*. Water-soluble near-infrared fluorescent heptamethine dye for lymphatic mapping applications. Bioorg. Med. Chem. Lett., 2022, 73: 128910
9. Guangyu Lin, Mei Hu, Rong Zhang, Yuanxing Zhu, Kedan Gu, Junping Bai, Jiyang Li*, Xiaochun Dong*, Weili Zhao*. Discovery of Meso-(meta-Pyridinium) BODIPY Photosensitizers: In Vitro and In Vivo Evaluations for Antimicrobial Photodynamic Therapy. J. Med. Chem., 2021, 64 (24): 18143-18157
10. Zhiliang Yu, Junliang Zhou,Xin Ji, Guangyu Lin, Shuang Xu, Xiaochun Dong*, Weili Zhao*. Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy. J. Med. Chem., 2020, 63 (17): 9950-9964
11. Kedan Gu, Guangyu Lin, Yuanxing Zhu, Xin Ji, Jiyang Li*, Xiaochun Dong*, Weili Zhao*. Anchoring BODIPY photosensitizers enable pan-microbial photo-inactivation. Eur. J Med. Chem., 2020, 199: 112361
12. Zhifeng Xia, Yanyang Nan, Chang Liu, Guangyu Lin, Kedan Gu, Cheng Chen, Weili Zhao, Dianwen Ju, XiaochunDong*. Design, Synthesis and Biological Evaluation of Novel1,2,5-Oxadiazol-3-Carboximidamide Derivatives as Indoleamine 2, 3-Dioxygenase 1(IDO1) Inhibitors. Anti-Cancer Agents in Medicinal Chemistry, 2020, 20: 1592-1603
