姓 名 | 吴伟 | 性 别 | 男 |
职 称 | 教授 | 学 历 | 理学博士（药剂学） |
电 话 | 021-51980084 | 传 真 | 021-51980084 |
电子邮件 | wuwei@shmu.edu.cn | 个人主页 |
|
通讯地址 | 上海市浦东新区张衡路826号科研楼729房间 | ||
1993.08 – 1996.07 第二军医大学药学院药剂学专业，医学硕士（导师：周全教授）
1988.08 – 1992.07 第二军医大学药学院药学专业，理学学士
工作经历 2013.1 复旦大学药学院药剂学教研室，教授、博士生导师
2007.2 复旦大学药学院药剂学教研室，教授、博士生导师，副院长
2006.2 复旦大学药学院药剂学教研室，副教授
2001.12 复旦大学药学院药剂学教研室，副教授，硕士研究生导师，教研室副主任、院长助理
2000.10 复旦大学药学院药剂学教研室，讲师
2000.03 – 2000.08 中国人民解放军第208医院药剂科，主管药师
1999.07 – 2000.03 中国人民解放军军事医学科学院毒药药物研究所
1992.07– 1993.08 中国人民解放军第208医院药剂科，药师
博士生导师
研究方向
药物载体给药系统体内时空命运
口服给药系统
药物新剂型与新技术
中国颗粒学会生物颗粒专委会副主任委员
世界中联中药药剂委员会第三届理事会副会长
中国药学会药剂专业委员会委员
中国医药生物技术协会纳米生物技术委员会常务委员
国家食品药品监督管理局药品审评专家
副主编: Chinese Chemical Letters、Journal of Biomedical Nanotechnology
特邀编辑：Acta Pharmaceutica Sinica B
编委: AAPS PharmSciTech、Acta Pharmaceutica Sinica B、Archives of Pharmacal Research、Asian Journal of Pharmaceutical Sciences、Current Drug Delivery、Drug Delivery Letters、Heliyon、International Journal of Pharmaceutics、Journal of Chinese Pharmaceutical Sciences、Journal of Drug Delivery Science and Technology、MedComm Biomaterials and Applications、Pharmaceutical Research、Pharmaceutics、Processes、《药学学报》、《中国医药工业杂志》、《药学进展》
客座编辑: Acta Pharmaceutica Sinica B、Advanced Drug Delivery Reviews、International Journal of Pharmaceutics、Pharmaceutical Research、Pharmaceutics
共发表SCI论文200余篇，Google Scholar引用1万余次。
1.Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang*, Weili Zhao*, Wei Wu*. Near-infrared Fluorophores with Absolute Aggregation-caused Quenching and Negligible Fluorescence Re-illumination for In vivo Bioimaging of Nanocarriers. Aggregate 2022, DOI: 10.1002/agt2.277
2.Haisheng He, Chang Liu, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao*, Wei Wu*. Accurate and Sensitive probing of micellization based on absolute aggregation-caused quenching effect. Aggregate 2022, DOI: 10.1002/agt2.163
3.Wei Wu*, Tonglei Li*. Deepening the understanding of the in vivo and cellular
4.Yifan Cai, Jianping Qi, Yi Lu, Haisheng He*, Wei Wu*. The in vivo fate of polymeric micelles. Adv Drug Deliv Rev 2022, 188: 114463.
5.Wufa Fan, Haixia Peng, Zhou Yu, Luting Wang, Haisheng He, Yuhua Ma, Jianping Qi, Yi Lu, Wei Wu*. The long-circulating effect of pegylated nanoparticles revisited via simultaneous monitoring of both the drug payloads and nanocarriers. Acta Pharm Sin B 2022, 12(5): 2479-2493.
6.Zichen Zhang, Jianping Qi, Yi Lu, Wei Wu*. An update on Oral Drug Delivery via Intestinal Lymphatic Transport. Acta Pharm Sin B 2021, 11(8): 2450-2469.
7.Zichen Zhang, Jianping Qi, Yi Lu, Wei Wu*, Hailong Yuan*. Peroral targeting of drug nanocarriers to sites beyond the gastrointestinal tract. Med Res Rev 2021, 41: 2590-2598.
8.Yinqian Yang, Yongjiu Lv, Chengying Shen, Tingting Shi, Haisheng He, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu*. In vivo dissolution of poorly water-soluble drugs: proof of concept based on fluorescence bioimaging. Acta Pharm Sin B 2021, 11: 1056-1068.
9.Haisheng He, Luting Wang, Yuhua Ma, Yinqian Yang, Yongjiu Lv, Zichen Zhang, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu*. The biological fate of orally administered mPEG-PDLLA polymeric micelles. J Control Release 2020, 327: 725-736.
10.Zhou Yu, Wufa Fan, Luting Wang, Jianping Qi, Yi Lu, Wei Wu*. Effect of surface charges on oral absorption of intact solid lipid nanoparticles. Mol Pharm 2019, 16: 5013-5024.
11.Wei Wu*, Tonglei Li*. Unraveling the in vivo fate and cellular pharmacokinetics of drug nanocarriers. Adv Drug Deliv Rev 2019, 143: 1-2.
12.Jianping Qi, Xiongwei Hu, Xiaochun Dong, Yi Lu, Weili Zhao, Wei Wu*. Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool. Adv Drug Deliv Rev 2019, 143: 206-225.
13.Haisheng He, Yi Lu, Jianping Qi, Quangang Zhu, Zhongjian Chen*, Wei Wu*. Adapting liposomes for oral drug delivery. Acta Pharm Sin B 2019, 9(1): 36-48.
14.Haisheng He, Sifan Jiang, Yunchang Xie, Yi Lu, Jianping Qi, Xiaochun Dong, Weili Zhao, Zongning Yin, Wei Wu*. Reassessment of long circulation via monitoring of integral polymeric nanoparticles justifies a more accurate understanding. Nanoscale Horizons 2018, 3: 397-407
15.Jianping Qi, Jie Zhuang, Yongjiu Lv, Yi Lu, Wei Wu*. Exploiting or overcoming the dome trap for enhanced oral immunization and drug delivery. J Control Release 2018, 275:92-106.
16.Haisheng He, Yi Lu, Jianping Qi, Weili Zhao, Xiaochun Dong, Wei Wu*. Biomimetic thiamine- and niacin-decorated liposomes for enhanced oral delivery of insulin. Acta Pharm Sin B 2018, 8(1): 97-105.
17.Yuhua Ma, Haisheng He, Fei Xia, Yingxia Li, Yan Lu, Daofeng Chen, Jianping Qi, Wei Zhang*, Yi Lu*, Wei Wu*. In vivo fate of lipid-silybin conjugate nanoparticles: implications on enhanced oral bioavailability. Nanomedicine: Nanotechnology, Biology and Medicine 2017, 13(8): 2643-2654.
18.Fei Xia, Wufa Fan, Sifan Jiang, Yuhua Ma, Yi Lu, Jianping Qi, Ejaj Ahmad, Xiaochun Dong, Weili Zhao*, Wei Wu*. Size-Dependent Translocation of Nanoemulsions via Oral Delivery. ACS Applied Materials & Interfaces 2017, 9(26):21660-21672.
19.Ejaj Ahmad, Yunhai Feng, Jianping Qi, Wufa Fan, Yuhua Ma, Haisheng He, Fei Xia, Xiaochun Dong, Weili Zhao, Yi Lu*, Wei Wu*. Evidence of nose-to-brain delivery of nanoemulsions: cargoes but not vehicles. Nanoscale 2017, 9(3): 1174-1183.
20.Haisheng He, Jian Zhang, Yunchang Xie, Yi Lu, Jianping Qi, Ejaj Ahmad, Xiaochun Dong, Weili Zhao*, Wei Wu*. Bioimaging of Intravenous Polymeric Micelles Based on Discrimination of Integral Particles Using an Environment-Responsive Probe. Mol Pharm 2016, 13(11): 4013-9.
21.Zhiqiang Tian, Qin Yu, Yunchang Xie, Li Xiang, Fengqian Li, Yi Lu, Xiaochun Dong, Weili Zhao, Jianping Qi*, Wei Wu*. Controlling release of integral lipid nanoparticles based on osmotic pump technology. Pharm Res 2016, 33(8): 1988-97.
22.Yunchang Xie, Sifan Jiang, Fei Xia, Xiongwei Hu, Haisheng He, Zongning Yin, Jianping Qi, Yi Lu, Wei Wu*. Glucan microparticles thickened with thermosensitive gels as potential carriers for oral delivery of insulin. J Mater Chem B 2016, 4, 4040-4048.
23.Yunchang Xie, Xiongwei Hu, Haisheng He, Fei Xia, Yuhua Ma, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu*, Wei Wu*. Tracking Translocation of Glucan Microparticles Targeting M Cells: Implications for Oral Drug Delivery. J Mater Chem B 2016, 4: 2864-2873.
24.Jian Chen, Fei Xia, Sifan Jiang, Yunchang Xie, Zhang Bei, Yi Lu, Wei Wu*. Transmembrane Delivery of Anticancer Drugs through Self-assembly of Cyclic Peptide Nanotubes. Nanoscale 2016, 8: 7127-7136.
25.Xiongwei Hu, Wufa Fan, Zhou Yu, Yi Lu, Jianping Qi, Jian Zhang, Xiaochun Dong, Weili Zhao*, Wei Wu*. Evidence does not support intact absorption of solid lipid nanoparticles via oral delivery. Nanoscale 2016, 8: 7024-7035. (Cover)
26.Yi Lu, Ye Li, Wei Wu*. Injected Nanocrystals for Targeted Drug Delivery. Acta Pharm Sin B 2016, 6(2): 106-113.
27.Xiongwei Hu, Jian Zhang, Zhou Yu, Yunchang Xie, Haisheng He, Jianping Qi, Weili Zhao*, Wei Wu*. Environment-responsive Aza-BODIPY Dyes Quenching in Water as Potential Probes to Visualize the in Vivo Fate of Lipid-based Nanocarriers. Nanomedicine: Nanotechnology, Biology, and Medicine 2015, 11(8): 1939-1948.
28.Mengmeng Niu, Ya’nan Tan, Peipei Guan, Lars Hovgaard, Yi Lu, Jianping Qi, Ruyue Lian, Xiaoyang Li, Wei Wu*. Enhanced oral absorption of insulin-loaded liposomes containing bile salts: a mechanistic study. Int J Pharm 2014, 460: 119-130.
29.Xingwang Zhang, Jianping Qi, Yi Lu, Xiaoyang Li, Wei He, Wei Wu*. Biotinylated liposomes as potential carriers for oral delivery of insulin. Nanomedicine: Nanotech Biol Med 2014, 10: 167-176.
30.Mengmeng Niu, Yi Lu, Lars Hovgaard, Peipei Guan, Yanan Tan, Ruyue Lian, Jianping Qi, Wei Wu*. Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. Eur J Pharm Biopharm 2012 81(2):265-72
31.Huifang Liu, Jian Chen, Qing Shen, Wei Fu*, Wei Wu*. Molecular insights on the cyclic peptide nanotube-mediated transportation of anti-tumor drug 5-fluorouracil. Mol Pharm 2010, 7(6): 1985-1994.
32.Yaping Chen, Yi Lu, Jianming Chen, Jie Lai, Jing Sun, Fuqiang Hu, Wei Wu*. Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt. Int J Pharm, 2009,376: 153-160.
33.Cheng Lu, Yi Lu*, Jian Chen, Wentong Zhang, Wei Wu*. Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system. Eur J Pharm Biopharm 2007,66:210-219.
34.Xiuli Wei, Ningyun Sun, Baojian Wu, Chunhua Yin, Wei Wu*. Sigmoidal release of indomethacin from pectin matrix tablets: Effect of in situ crosslinking by calcium cations. Int J Pharm 2006,318:132-138.
35.Wei Wu*, Yang Wang, Li Que. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur J Pharm Biopharm 2006,63(3):288-294.
