姓 名 | 冯美卿 | 性 别 | 女 |
职 称 | 教授 | 学 历 | 博士 |
电 话 | 021-51980035 | 传 真 | |
电子邮件 | fmq@fudan.edu.cn | 个人主页 | |
通讯地址 | 张衡路826号科研楼225 | ||
1985.08 – 1990.07 上海医科大学药学院 学士
1996.03 – 1999.03 石油大学（北京）化学工艺系 硕士
2001.09 – 2004.06 复旦大学药学院 博士
1990.07 – 1994.06 河北省药物研究所试验药厂
1994.07 – 2004.11 河北科技大学，化学与制药工程学院
2004.12 – 2014.12 复旦大学药学院 副教授
2014.12 – 至今 复旦大学药学院 教授
1. 上海市科委重点项目：抗癌药物CK-和蛋白激酶用于肝癌诊断中的子课题微生物转化法制备抗癌药物CK，（054319927）子课题负责人， 2005-2007
2. 国家自然基金项目：人参稀有皂甙微生物转化机制（途径）及代谢调节（30772676）2008-2010
3. 国家自然基金项目：重组HDL-药物复合物肝靶向性及其分子机制研究（30973684）2010年-2012年，
4. 国家自然基金项目：载脂蛋白AI介导小干扰RNA靶向至肝脏的相关机制及抗HBV作用研究（81341083）
2014-2015
5. 上海市纳米专项课题载脂蛋白A-I介导的重组HDL纳米粒肝靶向性及其机制研究（0952nm03500)，
2009-2011。
6. 上海市科委重点项目毕赤酵母表达人载脂蛋白A-I抗动脉粥样硬化成药性研究(12431900202)
2012-2015
7. 973项目肺癌在体分子分型的新型纳米分子成像探针基础研究(骨干（2015CB931800) 2015-2019
上海市科委科技进步 二等奖 排名第二
上海市药学会科技进步 三等奖 排名第二
1. 基因工程技术药物研发及应用
2. 天然产物为生物转化研究
2010.05 – 现在 上海药学会抗生素分会理事
Zhu HaiYan, Han Lei, et al, Feng Meiqing*. Baicalin Inhibits Autophagy Induced by Influenza A Virus H3N2. Antiviral Research. 2015; 113: 62-70.
Wang baolong Han Lei, et al, Feng Meiqing*. Combination of ApoA1 Modified Liposome-doxorubicin with Autophagy Inhibitors Overcame Drug resistance in Vitro. Pharmaceutical Sciences. 2014; 103:3994–4004.
Meiqing Feng, Ziwei Liao, Lei Han, Jiyang Li & Li Ye. Enhancement of microbial hydroxylation of 13-ethyl-gon-4-ene-3,17-dione by Metarhiziumanisopliae using anoliposome technique. Journal of Industrial Microbiology & Biotechnology. 2014; 41:619-627.
Li Ye, Jiajun Fan, et al, Meiqing Feng*, DianwenJu*. Tumor Necrosis Therapy Antibody Interleukin-2 Fusion Protein Elicits Prolonged and Targeted Antitumor Effects in vivo. Appl Microbiol Biotechnol. 2014; 98:4053–4061.
Jiajun Fan, Xian Zeng, Yubin Li, Shaofei Wang, Ziyu Wang, Yun Sun, MeiqingFeng*, DianwenJu*. Autophagy Plays a Critical Role in ChLym-1-Induced Cytotoxicity of Non-Hodgkin’s Lymphoma Cells. Plos One. doi:10.1371/journal.pone.0072478.
Baolong Wan ,Yuan Yuan, Lei Han, and Meiqing Feng*. Recombinant lipoproteins reinforce cytotoxicity of doxorubicin to hepatocellular carcinoma. J Drug Target, 2014; 22(1): 76–85.
Weina Wang, Wei Zhou, Baolong Wang, Haiyan Zhu, Meiqing Feng*. Antioxidant effect of apolipoprotein A-I on high-fat diet-induced non-alcoholic fatty liver disease in rabbits. Acta Biochimica et Biophysica Sinica. 2013; 45: 95–103.
Weina Wang, Xunlong Shi, Yuan Yuan, Haiyan Zhu, Wei Zhou, Hai Huang, and Meiqing Feng*. Inhibitory effect of apolipoprotein A-I on matrix metalloproteinase-2 expression in vivo and in vitro. Acta Biochim Biophys Sin. 2013; 45: 194–202.
Yuan Yuan, Weina Wang, Baolong Wang, Haiyan Zhu, Boheng Zhang, and Meiqing Feng*. Delivery of hydrophilic drug doxorubicin hydrochloride targeted liver using apoAI as carrier. Journal of Drug of Targeting. 2013.21(4): 367–374.
Li Ye, Chunyan Zhang, Jiyang Li, Xunlong Shi and Meiqing Feng*. Effects of external calcium on the biotransformation of ginsenoside Rb1 to ginsenoside Rd by Paecilomycesbainier 229-7. World J Microbiol Biotechnol. 2012 (28): 857–863.
Yang Ding, Wei Wang, Meiqing Feng*, Jianping Zhou*. A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy. Biomaterials. 2012 (33): 8893-8905.
Qin Yan, Wei Zhou, XunLong Shi, Pei Zhou, Dianwen Ju, Meiqing Feng*. Biotransformation pathways of ginsenoside Rb1 to compound K by_-glucosidases in fungus PaecilomycesBainier sp. 229. Process Biochemistry. 2010; 45: 1550–1556.
Li Ye, Chao-Qun Zhou, Wei Zhou, Pei Zhou, Dao-Feng Chen, Xiao-Hui Liu, Xun-Long Shi, Meiqing Feng*. Biotransformation of ginsenoside Rb1 to ginsenoside Rd by highly substrate tolerant Paecilomycesbainier 229-7. Bioresource Technology. 2010; 101: 7872–7876.
