卢燕
天然药物学, 副教授, 博士生导师


姓      名

 卢燕

性      别

 女

职      称

 教授

学      历

 博士

电      话

 021-51980157

传      真

 

电子邮件

 luyan@fudan.edu.cn

个人主页

 

通讯地址

   上海市张衡路826号化学实验北楼309室



教育经历 

1996.09 – 2003.07 山东中医药大学中药学院,本科、硕士
2003.09 – 2006.07 复旦大学药学院,博士 


工作经历

2006.07 – 2011.10 复旦大学药学院,讲师、副教授、教授
2011.11 – 2012.12 美国北卡莱罗那大学教堂山分校(UNC),访问学者
2011.11. – 目前 复旦大学药学院,副教授


承担科研项目情况

1.  国家自然科学基金面上项目,柽柳多糖-黄酮缀合物治疗病毒性肺炎的构效关系与协同作用机制(82173940)

2.  国家重点研发计划,中药的分子标识研究以及“中药智慧云”信息平台建设(2019YFC1711000)分任务

3. 西藏自治区重大科技专项,藏药“五味甘露浴”药效物质基础研究与数据库建设(XZ201801-GH-13)子课题

4. 西藏自治区中央引导地方项目,藏药清热类药物活性物质与靶标分子的研究XZ202001YD0003C子课题 

5. 国家自然科学基金面上项目,多基源藏药圆柏的清热药效物质基础与品质评价(81673690)
6. 科技部十二五“重大新药创制”重大科技专项,多糖类药物制备及质量控制关键技术研究(2012ZX09301001-003)子课题
7. 科技部十一五“重大新药创制”重大科技专项, 与药效相关的中药质量评价关键技术研究(2009ZX09502-021)子课题

8. 国家自然科学基金青年科学基金项目,鱼腥草的抗补体活性成分与清热解毒药效物质基础研究(30801508)

9. 2010、2015版《中国药典》一部标准研究,滇鸡血藤、复方鸡血藤膏、南五味子、通关藤、虎杖、狼毒、京大戟等


研究方向

1. 中草药的活性成分与质量评价

2. 中药提取物及其制剂的质量标准与产品开发


代表性成果

1.Yan Lu#, Ya-Si Huang#, Chin-Ho Chen, Toshiyuki Akiyama, Susan L. Morris-Natschke, Yung-Yi Cheng, Ih-Sheng Chen, Sheng-Zehn Yang, Dao-Feng Chen*, Kuo-Hsiung Lee*. Anti-HIV tigliane diterpenoids from Reutealis trisperma. Phytochemistry, 2020, 174: 112360

2.Yiting Yang#, Deji, Zelong Fu, Xieli Wang, Daofeng Chen, Hui Xie*, Yan Lu*. Molecular Identification Based on Chloroplast Sequences and Anti-complementary Activity Comparison of Juniperus Samples fromthe Qinghai-Tibet Plateau. Planta Medica, 2020, 86: 1176-1184.

3.Long Xia, Deji, Mengxia Zhu, Daofeng Chen*, Yan Lu*. Juniperus pingii var. wilsonii acidic polysaccharide: extraction, characterization and anticomplement activity. Carbohydrate Polymers, 2020, 231:115728.

4.Jiangyan Huo, Yan Lu*, Long Xia, Daofeng Chen*. Structural characterization and anticomplement activities of three acidic homogeneous polysaccharides from Artemisia annua. Journal of Ethnopharmacology, 2020, 247: 112281.

5.Haijuan Zhi, Xin Jin, Haiyan Zhu, Hong Li, Yunyi Zhang, Yan Lu*, Daofeng Chen*. Exploring the effective materials of flavonoids-enriched extract from Scutellaria baicalensis roots based on the metabolic activation in influenza A virus induced acute lung injury. Journal of Pharmaceutical and Biomedical Analysis, 2020, 177: 112876.

6.Yan Lu#, Juanjuan Zhang#, Jiangyan Huo, Daofeng Chen*. Structural characterization and anti-complementary activities of two polysaccharides from Houttuynia cordata. Planta Medica, 2019, 85: 1098-1106.

7.Beibei Li, Mengxue Dong, Ji De, Li Ye, Daofeng Chen, Yan Lu*. Structural characterization and anti-proliferation activities against tumor cells of an arabinogalactan from Juniperus convallium. Molecules, 2019, 24: 1850. 

8.Qianbo Song, Xiao Xia, Chongmin Ji, Daofeng Chen, Yan Lu*. Optimized flash extraction and UPLC-MS analysis on antioxidant compositions of Nitraria sibirica fruit. Journal of Pharmaceutical and Biomedical Analysis, 2019, 172: 379-387.

9.Zelong Fu#, Long Xia#, Ji De, Mengxia Zhu, Yan Lu*, Daofeng Chen*. Beneficial effects on H1N1-induced acute lung injury and structure characterization of anti-complementary acidic polysaccharides from Juniperus pingii var. wilsonii. International Journal of Biological Macromolecules, 2019, 129: 246-253.

10.Yan Lu#, Yun Jiang#, Lijun Ling, Yunyi Zhang, Hong Li, Daofeng Chen*. Beneficial effects of Houttuynia cordata polysaccharides on ‘two-hit’ acute lung injury and endotoxic fever in rats are associated with anti-complementary activities. Acta Pharmaceutica Sinica B, 2018, 8(2): 218-227. 


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