姓 名 | 黄建明 | 性 别 | 女 |
职 称 | 副教授 | 学 历 | 博士 |
电 话 |
| 传 真 | |
电子邮件 | jmhuang@shmu.edu.cn | 个人主页 |
|
通讯地址 | 上海浦东新区张衡路826号实验北楼211 |
1994.09 – 1997.07 上海医科大学药学院,生药学专业硕士
1999.09 – 2003.07 复旦大学药学院,生药学专业博士
工作经历
2000.09 – 今复旦大学药学院,讲师、副教授
1997.07 – 2000.08 上海医科大学药学院,助教
2012.08 – 2013.08 美国伊利诺伊大学芝加哥分校(UIC)药学院,访问学者
承担科研项目情况
主持国家、省部级研究课题3项,以及多项企业合作课题。
1.上海市科委科技支撑项目,平喘候选药物YFSKL的成药性研究 (13401900502)
2.国家自然科学基金青年科学基金项目,基于代谢组学的中国千金藤属植物化学分类学及资源品质研究(31100238)
3.上海市科委中药现代化专项基金项目,鞘蕊苏平喘有效部位的活性成分及药效学研究(09dZ1973202)
研究方向
药用植物的质量评价与新药研究,植物活性成分及其生物合成途径
发表科研论文70余篇,获中国专利授权10项。其中第一作者或通讯作者论文40余篇,代表论文如下:
[1] Shiting Wang#,Lulu Tian#, Yaqin Wang, Jiayong He, Yun Kang, Yan Shangguan, Wenqi Qian, Ping Yang,Jianming Huang*. Identification of alkaloidal compounds from leaves and rootsof Stephania succifera by HPLC-QTOF-MS and prediction of potential bioactivity with PharmMapper. Phytochemical Analysis, 2022, 33: 239–248.
[2] Yangyang Zhang, Yun Kang, Hui Xie, Yaqin Wang, Yaoting Li, Jianming Huang*. Comparative transcriptome analysis reveals candidate genes involved in isoquinoline alkaloid biosynthesis in Stephania tetrandra. Planta Medica, 2020, 86: 1258–1268.
[3] Wenqi Qian, Weilin Wu, Yun Kang, Yaqin Wang, Ping Yang, Yuanrong Deng, Chengjie Ni, Jianming Huang*. Comprehensive identification of minor components and bioassay-guided isolation of an unusual antioxidant from Azolla imbricata using ultra-high performance liquid chromatography–quadrupole time-of-flight mass spectrometry combined with multicomponent knockout and bioactivity evaluation. Journal of Chromatography A, 2020, 1609, 460435.
[4] Shiting Wang, Wenqi Qian, Peng He, Meiqing Feng, Yun Kang, Yaqin Wang, Jianming Huang*. Two new glycoalkaloids from Stephania succifera. Phytochemistry letter, 2019, 34, 99–102.
[5] Weilin Wu#, Wenqi Qian#, Haitian Hao, Yun kang, Yaqin Wang, Yuanrong Deng, Chengjie Ni, Jianming Huang*, Weiyu Weng*. Determination of caffeoylquinic acid derivatives in Azolla imbricata by chitosan-based matrix solid-phase dispersion coupled with HPLC–PDA. Journal of Pharmaceutical and Biomedical Analysis, 2019,163, 197–203.
[6] Yan Shangguan, Jiayong He, Yun Kang, Yaqin Wang, Ping Yang, Jixian Guo, Jianming Huang*. Structural characterisation of alkaloids in leaves and roots of Stephania kwangsiensis by LC-QTOF-MS. Phytochemical Analysis, 2018, 29, 101–111.
[7] Jiayong He, Ying Liu, Yun Kang, Ping Yang, Yaqin Wang, Jixian Guo, Jianming Huang*. Identification of Alkaloids in Stephania hainanensis by Liquid Chromatography Coupled with Quadrupole Time-of-flight Mass Spectrometry. Phytochemical Analysis, 2016, 27: 206–216.
[8] Daotao Xie, Yaqin Wang, Yun Kang, Qiufen Hu, Naya Su, Jianming Huang*, Chuntao Che, Jixian Guo. Microwave-assisted extraction of bioactive alkaloids from Stephania sinica. Separation and Purification Technology, 2014, 130: 173-181.
[9] Jiajun Yin, Yaqin Wang, Bo Tan, Yun Kang, Daotao Xie, Lulu Tian, Jianming Huang*. Matrix solid-phase dispersion extraction for chromatographic analysis of labdane diterpenoids in Coleus forskohlii. Phytochemical Analysis, 2013, 24: 117–123.
[10] Lulu Tian, Yaqin Wang, Yi Ling, Jiajun Yin, Jun Chen*, Jianming Huang*. A sensitive and specific HPLC-MS/MS analysis and preliminary pharmacokinetic characterization of isoforskolin in beagle dogs. Journal of Chromatography B, 2011, 879: 3688–3693.