教育经历
2016.09 - 2021.06 复旦大学，药理学，博士
2012.09 - 2016.06 沈阳药科大学，药学，学士
2025.03 - 至今 复旦大学药学院，青年研究员
2021.06 - 2025.02 复旦大学药学院，博士后
1. 天然多糖驱动的“肠-X轴”研究
2. 中药药理与中药化学生物学
3. 基于成体干细胞与类器官平台的活性天然产物发现策略
国家自然科学基金面上项目，主持，2026.01-2029.12
国家自然科学基金青年项目，主持，2023.01-2024.12
国家“博新”计划，主持，2022.7-2025.2
中国博士后科学基金面上项目，主持，2021.11-2025.02
复旦大学引进人才科研基金，主持， 2025.03-2028.05
复旦大学药学院“松德”青年人才培育计划，主持，2025.03-2028.03
上海市药理学会中西医结合药理学专业委员会委员
中国药学会中医肿瘤药物与临床研究专业委员会青年委员
World Journal of Integrated traditional and western Medicine (WJIM) 青年编委
2023年国家自然科学基金年度优秀资助成果，治疗炎症性肠病的新型潜在药物靶点研究
2023年复旦大学优秀博士后
第十届上海药学会药理学青年论文报告会，特等奖
2021年复旦大学“超级博士后”激励计划
1. 天然多糖驱动的“肠-X轴”研究
2. 中药药理与中药化学生物学
1. 专利：双酰肼结构类化合物其制备方法及其应用, 已授权, ZL201911089415.X
2. 专利：一类抑制肠道炎症反应的活性化合物, 已授权, ZL202010312884.X
3. 专利：虎耳草多糖及其在制备补体抑制剂及抗炎药物中的用, CN202311803666.6
1. Weilian Bao#, Yan You #, Jiahui Ni#, et al, Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells, Science Advances, 2023, 9(35):eadh5016
2. Weilian Bao#, Jiaren Lyu#, Guize Feng#, et al，Aloe emodin promotes mucosal healing by modifying the differentiation fate of enteroendocrine cells via regulating cellular free fatty acid sensitivity，Acta Pharmaceutica Sinica B, 2024, 14(9):3964-3982
3. Weilian Bao#, Xiaohong Liu#, Yan You#, et al，Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation，Pharmacological Research, 2021, 169:105679
4. Yan You#, Welian Bao#, Sulin Zhang, et al, Sorting nexin 10 mediates metabolic reprogramming of macrophages in atherosclerosis through the Lyn-dependent TFEB Signaling Pathway, Circulation Research, 2020, 127:534-549
5. Weilian Bao#, Qibiao Wu#, Bin Hu, et al, Oral nanoparticles of SNX10-shRNA plasmids ameliorate mouse colitis, International Journal of Nanomedicine, 2021, 16:345-357
6. Weilian Bao, Keyuan You, Guize Feng, et al, Construction and application of a novel mouse model of colitis with the function evaluating effects of anti-inflammatory and pro-stemness, Fudan University Journal of Medical Sciences, 2022, 49:979-986
7. Linfeng Guo, Weilian Bao, Shuiyuan Yang, et al, Rhei Radix et Rhizoma in Xuanbai-Chengqi decoction strengthens the intestinal barrier function and promotes lung barrier repair in preventing severe viral, Journal of Ethnopharmacology, 2024, 319(Pt 2):117231
8. Shiyu Xue, Weilian Bao, Changyue Wang et al, In vitro nephrotoxicity and structure-toxicity relationships of eight natural aristolactams, Toxicon, 2025, 254:108214
9. Huaichang Zhu, Lishuang Zhou, Weilian Bao, et al, Acetate produced by the interaction between Houttuynia pectin and Phocaeicola vulgatus alleviated H1N1-induced acute lung injury in mice through the GPR43/JAK2/STAT3 pathway, Carbohydrate Polymers, 2025, 124280
10. Yang Liu#, Yan Lu#, Weilian Bao#, et al, Quercitrin inhibits NETosis via Histone H3 to alleviate the severity of viral pneumonia with drug-resistant bacteria co-infection in mice, Phytotherapy Research, 2026, ptr.70190
11. Sulin Zhang, Zhiwen Yang, Weilian Bao, et al, SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC, Autophagy, 2020, 6(4):735-749
12. Guize Feng, Lijie Zhang, Weilian Bao, et al, Gentisic acid prevents colorectal cancer metastasis via blocking GPR81-mediated DEPDC5 degradation, Phytomedicine, 2024, 129:155615
13. Ziyan Xu, Changyue Wang, Weilian Bao, et al, In vitro nephrotoxicity and quantitative UPLC-MS analysis of three aristololactams in Houttuynia cordata, Journal of Pharmaceutical and Biomedical Analysis, 2023, 227:115289
