孙涛
药剂学, 副教授, 硕士生导师

姓      名

孙涛

性      别

职      称

副教授

学      历

博士

电      话

021-51980187

传      真

021-51980079

电子邮件

sunt@fudan.edu.cn

个人主页

http://smartdds.fudan.edu.cn/jiangchen/Index.aspx

通讯地址

上海市浦东新区张衡路826号复旦大学药学院


教育经历
2003.09–2007.06 山东大学化学与化工学院,本科
2007.09–2012.06 山东大学化学与化工学院,硕博连读
2010.09–2011.09 法国巴黎高师化学系联合培养,博士
  
工作经历 
2012.12–2015.9 苏黎世联邦理工学院,博士后

2015.09–2018.11 复旦大学药学院药剂学教研室,青年副研究员

2018.12–今 复旦大学药学院药剂学教研室,副教授


专家类别
副教授,硕士生导师


承担科研项目情况

1. 瑞士诺华集团博士后研究基金主持,2012-2015,结题)

2. 复旦大学引进人才科研基金(主持,2015-2018,结题)

3. 上海市青年科技英才扬帆计划基金主持,2016-2019,结题)

4. 复旦大学老年医学专项支持计划青年学者创新研究项目主持,2016-2018,结题)

5. 国家自然科学基金青年科学基金项目主持,2016-2019,结题)

6. 智能化递药教育部重点实验室开放课题主持,2016-2018,结题)

7. 复旦大学附属中山医院闵行分院-复旦大学药学院战略合作研究融合基金(主持,2017-2019,结题)

8. 复旦大学药学院-上海药物所合作研究课题融合基金(主持,2018-2021,结题

9. 复旦大学2025卓学计划主持,2020-2025,在研

10. 上海人社上海人才发展资金(主持,2021-2022,在研

11. 国家自然科学基金“肿瘤演进与诊疗的分子功能可视化”研究重大研究计划,培育项目(主持,2021-2023,在研

12. 上海市科委面上项目(主持,2022-2025,在研)

 

获奖及荣誉

2021年 上海药学科技奖,一等奖(2/2)

2020年 英国皇家化学会,新锐科学家

2019年 全国高校药学类青年教师教学能力大赛,特等奖

2019年 全国高校药学类青年教师微课教学大赛,一等奖

2019年 上海药学会药剂学年会论文报告会,二等奖

2019年 复旦大学上海医学院第二届课程思政教案大赛,三等奖

2018年 美国药剂师协会年会,Best Abstract

2018年 上海药学会药剂学年会论文报告会,优胜奖

2018年 复旦大学德传奖教金

2015年 第十届中国海外留学人员春晖杯竞赛优胜奖

2012年 山东大学优秀毕业生,山东省优秀毕业生

2010年 中国大学生“挑战杯”创业计划竞赛,省特等奖,国家银奖

2009年 第十一届“挑战杯”全国大学生课外学术科技作品竞赛,省特等奖,国家二等奖

 

研究方向

1.超分子药物递送系统:强调分子设计,利用刺激敏感型动态共价键,精准识别致病因子,对话于病灶微环境,实现药物智能负载、高效靶向与体内可视化定位释放。
2.功能性药物递送系统:设计构筑递药基元,拓展药物递送系统功能,合理改造母体药物,致力于阐明药物递送系统中的盲区。

 

社会任职

2021年6月起,任SCI收录期刊《Chinese Chemical Letters》(IF 6.779)青年编委

2020年6月起,任SCI收录期刊《Current Gene Therapy》(IF 4.391)编委

2021年6月起,上海药学会药剂青年学组,委员兼秘书

 

代表论著

2009年来, 以通讯/第一作者身份,在国际重要学术期刊上发表多篇SCI论文, 包括ACS Nano, Nano Lett, Adv Sci, Biomaterials, J Control Release, Small等30余篇, 共被引用逾2000次,H因子25。近年代表性论文如下:

30.  T. Sun, C. Li, X. Li, H. Song, B. Su, H. You, T. Zhang, C. Jiang,* Pharmaceutical Nanotechnology, 2022, Springer Nature Publish Group, Micro/Nano Technologies, Ning Gu (Eds): Nanomedicine (Chapter 10).

29. Q. Chen#, Q. Wang#, Y. Wang#, Y. Chu, Y. Luo, H. You, B. Su, C. Li, Q. Guo, T. Sun,* C. Jiang,* Penetrating Micelle for Reversing Immunosuppression and Drug Resistance in Pancreatic Cancer Treatment, Small 2022, DOI: 10.1002/smll.202107712.

28. Y. Chu, T. Sun,* C. Jiang,* Emerging Landscapes of Nanosystems Based on Pre-Metastatic Microenvironment for Cancer Theranostics. Chinese Chemical Letters 2022, DOI: https://doi.org/10.1016/j.cclet.2022.02.051.

27. Y. Chu, T. Sun,* Z. Xie, K. Sun,* C. Jiang,* Physicochemical Characterization and Pharmacological Evaluation of Novel Propofol Micelles with Low-Lipid and Low-Free Propofol. Pharmaceutics 2022, 14 (2), 414.

26. H. Chen#, T. Sun#, W. Zeng#, X. Zeng, L. Mei,* C. Jiang,* Y. Zhao.* NIR-Light-Intensified Hypoxic Microenvironment for Cascaded Supra-Prodrug Activation and Synergistic Chemo/Photodynamic Cancer Therapy. ACS Materials Letters 2022, 4, 111-119 (#co-first authors).

25. 纳米仿生型肿瘤疫苗的研究进展。杨玥#,王海燕#,孙野#孙涛*,蒋晨,药学学报2022,ASAP.

24. T. Sun, G. Zhang, T. Ning, Q. Chen, Y. Chu, Y. Luo, H. You, B. Su, C. Li, Q. Guo, C. Jiang.* A Versatile Theranostic Platform for Colorectal Cancer Peritoneal Metastases: Real-Time Tumor-Tracking and Photothermal-Enhanced Chemotherapy. Advanced Science 2021, 2102256.

23. C. Li, T. Sun,* C. Jiang.* Recent advances in nanomedicines for the treatment of ischemic stroke. Acta Pharmaceutica Sinica B 2021, 11, 7, 1767-1788.

22. C. Li#, Z. Xie#, Q. Chen, Y, Zhang, Y. Chu, Q. Guo, W. Zhou, Y. Zhang, P.  Liu, H. Chen, C. Jiang,* K. Sun,* T. Sun.Supramolecular Hunter Stationed on Red Blood Cells for Detoxification Based on Specific Molecular Recognition. ACS Nano 2020, 14, 4950-4962.

21. T. Sun#, Y. Ding#, X. Wang, K. Zhang, G.-P. Zhang, D. Liang, K. Yu, Y. Chu, Q. Chen, C. Jiang.* Carry-On Nitric-Oxide-Luggage for Enhanced Chemotherapeutic Efficacy. Nnao Letters 2020, 20, 5275-5283 (#co-first authors).

20. T. Sun, G. Zhang, Z. Guo, Q. Chen, Y. Zhang, Y. Chu, Q. Guo, C. Li, W. Zhou, Y. Zhang, P. Liu, H. Chen, H. Yu, L. Jiang, C. Jiang.* Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy fortumor theranostic. Journal of Controlled Release 2020, 321, 483-496.

19. Q. Wang, X. Guo, Y. Chen, Z. Wu, Y. Zhou, S. Sadaf, L. Han, X. Ding,* T. Sun.* Theranostics system caged in human serum albumin as a therapy for breast tumors. Journal of Materials Chemistry B 2020, 8, 6877-6885 (Invited paper).

18. D. Gao, Q. Zhu, J. Ruan, T. Sun,* L. Han.* Polyplexes by polymerized dequalinium and bi-functional aptamer for mitochondrial targeting drug release to overcome drug resistance. ACS Applied Bio Materials 2020, 3, 8, 5182-5192.

17. T. Sun, G. Zhang, Q. Wang, Z. Guo, Q. Chen, X. Chen, Y. Lu, Y. Zhang, Y. Zhang, Q. Guo, X. Gao, Y. Cheng, C. Jiang*, Pre-blocked molecular shuttle as an in-situ real-time theranostics. Biomaterials 2019, 204, 46-58.

16. T. Sun, G. Zhang, Q. Wang, Q. Chen, X. Chen, Y. Lu, L. Liu, Y. Zhang, X. He, C. Ruan, Y. Zhang, Q. Guo, C. Jiang*, A targeting theranostics nanomedicine as an alternative approach for hyperthermia perfusion. Biomaterials 2018, 183, 268-279.

15. C. Ruan, L. Liu, Q. Wang, X. Chen, Q. Chen, Y. Lu, Y. Zhang, X. He, Y. Zhang, Q. Guo, T. Sun,* C. Jiang, Reactive Oxygen Species-Biodegradable Gene Carrier for the Targeting Therapy of Breast Cancer. ACS Applied Materials & Interfaces 2018, 10, 10398-10408.

14. C. Ruan, L. Liu, Y. Lu, Y. Zhang, X. He, X. Chen, Y. Zhang, Q. Chen, Q. Guo, T. Sun,* C. Jiang, Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma. Acta Pharmaceutica Sinica B 2018, 8(1), 85-96.

13. T. Sun, X. Jiang, Q. Wang, Q. Chen, Y. Lu, L. Liu, Y. Zhang, X. He, C. Ruan, Y. Zhang, Q. Guo, Y. Liu, C. Jiang*, Substance P Mediated DGLs Complexing with DACHPt for Targeting Therapy of Glioma. ACS Applied Materials & Interfaces 2017, 9, 34603-34617.

12. T. Sun, Q. Wang, Y. Bi, X. Chen, L. Liu, C. Ruan, Z. Zhao, C. Jiang*, Supramolecular amphiphiles based on cyclodextrin and hydrophobic drugs. Journal of Materials Chemistry B 2017, 5, 2644-2654.

11. T. Sun, L. Shu, J. Shen, C. Ruan, Z. Zhao, C. Jiang*, Photo and redox-responsive vesicles assembledfrom Bola-type superamphiphiles. RSC Advances 2016, 6, 52189-52200.

10. T. Sun, A. Morger, B. Castagner*, J.-C. Leroux*, An oral redox-sensitive self-immolating prodrug strategy. Chemical Communications 2015, 51, 5721-5724.

9. T. Sun, H. Yan, P. Xing, J. Su, S. Li, A. Hao*, Cu (II)-triggered release of paclitaxel from a supramolecular complex. Supramolecular Chemistry 2013, 25 (5), 302-3095.

8. T. Sun, M. Ma, H. Yan, J. Shen, J. Su, A. Hao*, Vesicular particles directly assembled from the cyclodextrin/UR-144 supramolecular amphiphiles. Colloids and Surface A 2013, 424, 105-1126.

7. P. Xing#T. Sun#, A. Hao*, Vesicles from supramolecular amphiphiles. RSC Advances 2013, 3 (47), 24776-24793 (#co-first authors).

6. T. Sun, Q. Guo, C. Zhang, J. Hao, P. Xing, J. Su, S. Li, A. Hao*, G. Liu*, Vesicles with functional macrocyclic host sites confined in the bilayer as drug carriers. Langmuir 2012, 28, 8625-8636. 

5. T. Sun, H. Yan, G. Liu, J. Hao, J. Su, S. Li, P. Xing, A. Hao*, Strategy of directly employing paclitaxel to construct vesicles. Journal of Physical Chemistry B 2012, 116 (50), 14628-14636.

4. T. Sun, J. Shen, H. Yan, J. Hao, A. Hao*, Stable vesicles assembled by “supramolecular amphiphiles” with double hydrophobic chains. Colloids and Surface A 2012, 414, 41-49.

3. T. Sun, Y. Li, H. Zhang, J. Li, F. Xin, L. Kong, A. Hao*, pH-reversible vesicles based on the 'supramolecular amphiphilies' formed by cyclodextrin and anthraquinone derivate. Colloids and Surface A 2011, 375, 87-96.

2. T. Sun, H. Zhang, L. Kong, H. Qiao, Y. Li, F. Xin, A. Hao*, Controlled transformation from nanorods to vesicles induced by cyclomaltoheptaoses (β-cyclodextrins). Carbohydrate Research 2011, 346, 285-293.

1. T. Sun#, H. Zhang#, H. Yan, J. Li, G. Cheng, A. Hao*, H. Qiao, F. Xin, Sensitive fluorescent vesicles based on the supramolecular inclusion of β-cyclodextrin with N-alkylamino-1-anthraquinone. Supramolecular Chemistry 2011, 23(5), 351-364 (#co-first authors).

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