1. Kudelaidi Kuerban, Xiwen Gao, Hui Zhang, Jiayang Liu, Mengxue Dong, Lina Wu, Ruihong Ye, Meiqing Feng,
Li Ye*. Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer.
Acta Pharmaceutica Sinica B. 2020, 10(8): 1534-1548. doi:10.1016/j.apsb.2020.02.002 (IF=7.097) 通讯作者
2. Ke Wang, Kudelaidi Kuerban, Qi Wan, Zhihui Yu, Li Ye*, Ying Chen*. Introduction of Mercaptoethyl at Sorafenib Pyridine-2-Amide Motif as a Potentially Effective Chain to Further get Sorafenib-PEG-DGL. Molecules. 2020, 25: 573. doi:10.3390/molecules25030573 (IF=3.267) 共同通讯作者
3. Mengxue Dong, Zhefeng Meng, Kudelaidi Kuerban, Feilong Qi, Jiayang Liu Yuxi Wei, Qian Wang, Shanshan Jiang, Meiqing Feng,
Li Ye*. Diosgenin promotes anti-tumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota.
Cell Death and Disease. 2018, 9:1039 (IF=5.959)
4. Mengxue Dong, Tao Ye, Yongyan Bi, Qian Wang, Kudelaidi Kuerban, Jiyang Li, Meiqing Feng, Ke Wang, Ying Chen*,
Li Ye*. A novel hybrid of 3-benzyl coumarin seco-B-ring derivative and phenylsulfonylfuroxan induces apoptosis and autophagy in non-small-cell lung cancer.
Phytomedicine. 2019, 52: 79-88 (IF=4.18)
5. Qian Wang, Yalan Guo, Shanshan Jiang, Mengxue Dong, Kudelaidi Kuerban, Jiyang Li, Meiqing Feng, Ying Chen,
Li Ye*. A hybrid of coumarin and phenylsulfonylfuroxan induces caspase-dependent apoptosis and cytoprotective autophagy in lung adenocarcinoma cells.
Phytomedicine. 39 (2018) 160-167 (IF=4.18)
6. Yunxiang Ji, Qian Wang, Qian Zhao, Shuwei Zhao, Li Li, Guangbin Sun*,
Li Ye*. Autophagy suppression enhances DNA damage and cell death upon treatment with PARP inhibitor Niraparib in laryngeal squamous cell carcinoma.
Applied Microbiology and Biotechnology. 2019, 103: 9557-9568 (IF=3.67)
7. Ping Song, Ziyu Wang, Xuyao Zhang, Jiajun Fan, Yubin Li, Qicheng Chen, Shaofei Wang, Peipei Liu, Jingyun Luan,
Li Ye*, Dianwen Ju*. The role of autophagy in asparaginase-induced immune suppression of macrophages.
Cell Death and Disease. 2017(8): e2721 (IF=5.638)
8. Yongbin Wang, Qian Wang, Kudelaidi Kuerban, Mengxue Dong, Feilong Qi, Gang Li, Jie Ling, Wei Qiu, Wenzhong Zhang,
Li Ye*. Colonic electrical stimulation promotes colonic motility through regeneration of myenteric plexus neurons in slow transit constipation beagles.
Bioscience Report, 2019(39): BSR20182405.
9. Feilong Qi, Chen Zhang, Shanshan Jiang, Qian Wang, Kudelaidi Kuerban, Man Luo, Mengxue Dong, Xinguang Zhou, Laiming Wu, Biao Jiang,
Li Ye*. S-ethyl ethanethiosulfinate, a derivative of allicin, induces metacaspase-dependent apoptosis through ROS generation in Penicillium chrysogenum.
Bioscience Report, 2019(39): BSR20190167
10. Shanshan Jiang, Qian Wang, Meiqing Feng, Jiyang Li, Zhongbin Guan, Duopeng An, Mengxue Dong, Yuzhe Peng, Kudelaidi Kuerban,
Li Ye*. C2-ceramide enhances sorafenib-induced apoptosis via Caspase-dependent and PI3K/AKT/mTOR siginaling pathways in HCC cells.
Appl. Microbiol Biotechnol. 2017, 101:1535-1546. (IF=3.340)
11. Jiyang Li, Weina Wang, Lei Han, Meiqing Feng, Hui Lu, Li Yang, Xiangxiang Hu, Si Shi, Shanshan Jiang, Qian Wang,
Li Ye*. Human apolipoprotein A-I exerts a prophylactic effect on high fat diet-induced atherosclerosis in a rabbit model via inflammation inhibition.
Acta Biochimica et Biophysica Sinica. 2017, 49(2), 149-158. (IF=2.2)
12. Xiangxiang Hu, Si Shi, Huan Wang, Xiaocheng Yu, Qian Wang, Shanshan Jang,Dianwen Ju,
Li Ye*, Meiqing Feng*. Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo.
Scientific Report. 2017, 7:4559. (IF=4.122)
13. Qicheng Chen#,
Li Ye#, Jiajun Fan, Xuyao Zhang, Ping Song, Ziyu Wang, Shaofei Wang, Yubin Li, Jingyun Luan, Yichen Wang, Wei Chen, Wenjing Zai, Ping Yang, Zhonglian Cao, Dianwen Ju. Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase in vitro and in vivo.
Oncotarget, 2017, 8(53): 91052-91066 (IF=5.168)
14. Shanshan Jiang, Jiajun Fan, Qian Wang, Dianwen Ju, Meiqing Feng, Jiyang Li, Zhong-bin Guan, Duopeng An, Xin Wang,
Li Ye*. Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells.
Phytomedicine. 2016, 23: 243-252. (IF=3.526)
15.
Li Ye, Jiajun Fan, Xunlong Shi, Qun Tao, Dan Ye, Zongshu Xian, Xian Zeng, Yubin Li, Meiqing Feng, Dianwen Ju. Tumor necrosis therapy antibody interleukin-2 fusion protein elicits prolonged and targeted antitumor effects in vivo.
Appl. Microbiol Biotechnol. 2014, 98: 4053-4061.(IF=3.337)
16. Ping Song#,
Li Ye#, Jiajun Fan, Yubin Li, Xian Zeng, Ziyu Wang, Shaofei Wang, Guoping Zhang, Ping Yang, Zhonglian Cao, Dianwen Ju. Asparaginase induced apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells.
Oncotarget. 2015, 6(6): 3861-3873. (IF=5.168)
17. Meiqing Feng, Ziwei Liao, Lei Han, Jiyang Li,
Li Ye*. Enhancement of microbial hydroxylation of 13-ethylgon-4-ene-3,17-dione by Metarhizium anisopliae using nanoliposome technique.
J. Ind. Microbiol. Biotechnol. 2014, 41(4): 619-627. (IF=2.439)
18.
Li Ye#, Chunyan Zhang#, Jiyang Li, Xunlong Shi, Meiqing Feng. Effects of external calcium on the biotransformation of ginsenoside Rb1 to ginsenoside Rd by Paecilomyces bainier 229-7.
World J. Microbiol. Biotechnol. 2012, 28(3): 857-863. (IF=1.262)
19.
Li Ye,Xiao-Hui Liu,Wei Zhou,Mei-Qing Feng,Xun-Long Shi,Ji-Yang Li,Dao-Feng Chen,Pei Zhou,Microbial transformation of astragalosides to astragaloside IV by Absidia corymbifera AS2,
Process Biochem, 2011, 46(9): 1724-1730.
20. Li Ye,Chao-Qun Zhou,Wei Zhou,Pei Zhou,Dao-Feng Chen,Xiao-Hui Liu,Xun-Long Shi,Mei-Qing Feng,Biotransformation of ginsenoside Rb1 to ginsenoside Rd by highly substrate-tolerant Paecilomyces bainier 229-7,Bioresour. Technol., 2010, 101(20): 7872-787.
发明专利
1. 金龟子绿僵菌突变株及其在甾体化合物羟化反应中的应用,授权专利,ZL 2011 1 0199550.7
2. 一种通过微生物转化黄芪总皂苷制备黄芪甲苷的方法,授权专利,ZL 2010 1 0615265.4
3. 一种利用微生物转化制备人参皂苷Rd的方法,授权专利,ZL 2011 1 0207782.2
4. 去氧孕烯中间体纳米脂质体生物转化的优化方法,ZL 2013 1 0484977.0