Patrick M. Sexton


姓      名

 Patrick M. Sexton

性      别


职      称


学      历


电      话


传      真









Patrick M. Sexton 博士是世界著名药理学家,为“Sexton-Wootten方程式”的创始人之一,在G蛋白偶联受体的研究领域建树颇多,擅长于受体变构调节、配体趋势性信号偏向转导、B型G蛋白偶联受体及其辅助蛋白的结构与功能研究等。现任澳大利亚莫纳什大学药学研究所教授、国家新药筛选中心科技顾问等。他先后发表了230余篇研究论文,现任5家国际著名学刊的编委,2014年入选汤森路透社药理学和毒理学研究高被引用科学家。

Dr. Patrick Sexton is a world leading scientist in the field of G protein-coupled receptors (GPCRs), and in particular with respect to allosteric modulation of receptors, ligand-directed signal bias and structure/function of class B GPCRs and accessory proteins. His research crosses industry and academic boundaries through elucidation of fundamental biology and the intersection of this with drug-receptor interactions. He has authored over 230 publications, with major contributions to understanding of the distribution of receptors, the structural interface between peptide ligands and receptors, modulation of receptors by accessory proteins, detection and quantification of small molecule allosteric drug effects and ligand-biased signalling. He is a 2014 Thomson Reuters highly cited researcher in pharmacology and toxicology.



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