程志红
生药学, 副研究员 ,硕士生导师

姓      名

 程志红

性      别

 男

职      称

 副研究员

学      历

 博士

电      话

 021-51980157

传      真

 021-51980017

电子邮件

 chengzhh@fudan.edu.cn

个人主页

 

通讯地址

 上海市浦东新区张衡路826号复旦大学药学院

教育经历

1998.09 – 2003.06 中国药科大学中药学院,生药学博士
1994.09 – 1998.06 中国药科大学中药学院,中药分析学学士

 

工作经历
2009.01 – 今 复旦大学药学院,副研究员
2005.10 – 2008.08 美国马里兰大学(University of Maryland at College Park),博士后
2003.07 – 2005.09 中科院上海有机化学研究所,博士后


社会任职

2010.10 – 现在  上海市药学会生药学专业委员会委员

2014.06 – 现在  《中国生化药物杂志》编委

2015.12 – 现在  SCI收录期刊《Current Analytical Chemistry》 编委

  
获奖及荣誉
2011.01 教育部自然科学二等奖-麦冬类中药的系统研究(第三完成人)


承担科研项目情况
1.国家自然科学基金面上项目: 维药天山堇菜和一枝蒿治疗重症流感的物质基础研究(81473421, 2015.1-2018.12);
2.国家自然科学基金面上项目: 基于补体抑制作用探讨紫花地丁和夏枯草的清热药效物质(81073025, 2011.1-2013.12);
3.上海市科委中药现代化专项基金:紫花地丁清热药效物质基础及其对急性肺损伤的防治作用(09dZ1970100, 2009.6-2012.6);
4.教育部博士点基金(新教师类):清热药夏枯草的清热药效物质基础研究(20100071120052, 2011.1-2013.12);
5.“国家重大新药创制” 科技重大专项课题:中药药效物质基础及物质资源库研究关键技术(2009ZX09502-013, 2009.1-2010.12, 课题副组长);
6.2010国家药品标准提高研究课题:五加皮药材、五加皮饮片国家标准的制定研究(2010.9-2012.12)。

 

 
研究方向
1. 中草药的药效物质基础及质量控制研究;
2. 小分子天然产物的微生物转化研究。
代表性论著
 

[1]      Yiqing Wu, Chengle Yin, Yue Cao, Xin Liu, Jinxiang Yu, Jian Zhang, Boyang Yu, Zhihong Cheng*. Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis. Journal of Molecular Catalysis B: Enzymatic, 2017, DOI: 10.1016/j.molcatb.2017.02.008;

[2]      Dongsheng Du, Yan Lu, Zhihong Cheng*, Daofeng Chen*. Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities. Journal of Ethnopharmacology, 2016, 193: 345-353.

[3]      Yan Qin, Yingming Pang, Zhihong Cheng*. Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica. Phytochemical Analysis, 2016, 27(6): 364-374.

[4]      Chengle Yin, Jinge Zhou, Yiqing Wu, Yue Cao, Tao Wu, Shoude Zhang, Honglin Li, Zhihong Cheng*. Pterocarpans and triterpenoids from Gueldenstaedtia verna. Fitoterapia, 2015, 106: 46-54.

[5]      Dongsheng Du, Zhihong Cheng*, Daofeng Chen*. Anti-complement sesquiterpenes from Viola yedoensis. Fitoterapia, 2015, 101: 73-79.

[6]      Jie Cao, Chengle Yin, Yan Qin, Zhihong Cheng*, Daofeng Chen. Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis. Journal of Mass Spectrometry, 2014, 49: 1010-1024.

[7]      Guodong Xiao, Guowen Li, Liang Chen, Zijia Zhang, Jun-Jie Yin, Tao Wu*, Zhihong Cheng*, Xiaohui Wei, Zhengtao Wang. Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. Journal of Chromatography A, 2010, 1217: 5470-5476.

[8]      Zhihong Cheng, Huiping Zhou, Marla Luther, Junjie Yin, Liangli (Lucy) Yu*. Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and key genes for cholesterol biosynthesis and metabolism in primary rat hepatocytes. Journal of Agricultural & Food Chemistry, 2008, 56(13): 5033-5042.

[9]      Zhihong Cheng, Huiping Zhou, Junjie Yin, Liangli Yu*. Electron spin resonance estimation of hydroxyl radical scavenging capacity for lipophilic antioxidants. Journal of Agricultural & Food Chemistry, 2007, 55: 3325-3333.

[10]  Zhihong Cheng, Yinlong Guo*, Haoyang Wang, Guoqiang Chen. Qualitative and quantitative analysis of quaternary ammonium alkaloids from Rhizoma Corydalis by MALDI-FTMS coupled with a special precipitation reaction using Reinecke salt. Analytica Chimica Acta, 2006, 555: 269-277.

[11]  Zhihong Cheng, Boyang Yu?, Cordell Geoffrey A., Shengxiang Qiu*. Biotransformation of quinovic acid glycosides by microbes: direct conversion of the ursane to the oleanane triterpene skeleton by Nocardia sp. NRRL 5646. Organic Letters, 2004, 6: 3163-3165.

[12]  Zhihong Cheng, Tao Wu, Bligh S. W. Annie*, Bashall Alan, Boyang Yu*. cis-Eudesmane sesquiterpene glycosides from Liriope muscari and Ophiopogon japonicus. Journal of Natural Products, 2004, 67: 1761-1763.

[13]  Zhihong Cheng, Boyang Yu*, Xiuwei Yang. 27-Nortriterpenoid glycosides from Mitragyna inermis. Phytochemistry, 2002, 61: 379-382.

[14]  Zhihong Cheng (edited by Chinese Pharmacopoeia Commission), Pharmacopoeia of the People's Republic of China (2010, Vol. I). Beijing: China Medical Science Press, 2011.7; (中华人民共和国药典英文版2010年版第一卷的编委之一);

[15]  Zhihong Cheng, Huiping Zhou, Junjie Yin. Application of ESR in determination of wheat antioxidants. 2007. In WHEAT ANTIOXIDANTS (Edited by Liangli Yu). pp 173-189, John Wiley & Sons, Inc., Hoboken, NJ, USA.

 
 

 
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